STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Cthe_0405PFAM: glycoside hydrolase family 5; Dockerin type 1; KEGG: csc:Csac_1078 cellulose 1,4-beta-cellobiosidase; Belongs to the glycosyl hydrolase 5 (cellulase A) family. (526 aa)    
Predicted Functional Partners:
cipA
Cellulosome anchoring protein cohesin region; Acts as a scaffolding protein in the cellulosome. It promotes binding of cellulose to the catalytic domains of the cellulolytic enzymes.
  
   0.867
celI
Glycoside hydrolase family 9; This enzyme catalyzes the endohydrolysis of 1,4-beta- glucosidic linkages in cellulose, lichenin and cereal beta-D-glucans. Principally active against barley beta-glucan; Belongs to the glycosyl hydrolase 9 (cellulase E) family.
 
  
 0.865
bglA
TIGRFAM: beta-galactosidase; KEGG: dtu:Dtur_1799 beta-galactosidase; PFAM: glycoside hydrolase family 1; Belongs to the glycosyl hydrolase 1 family.
    
 0.865
Cthe_0071
KEGG: cpy:Cphy_3368 cellulose 1,4-beta-cellobiosidase; PFAM: glycoside hydrolase family 48; type 3a cellulose-binding domain protein.
  
 0.862
rsgI4
Type 3a cellulose-binding domain protein; Anti-sigma factor for SigI4. Negatively regulates SigI4 activity through direct interaction. Binding of the polysaccharide substrate to the extracellular C-terminal sensing domain of RsgI4 may induce a conformational change in its N-terminal cytoplasmic region, leading to the release and activation of SigI4.
    0.834
Cthe_0624
Glycoside hydrolase family 9; KEGG: cce:Ccel_0429 PKD domain containing protein; PFAM: glycoside hydrolase family 9; Dockerin type 1; PKD domain containing protein; SMART: PKD domain containing protein.
 
  
 0.831
Cthe_0271
PFAM: type 3a cellulose-binding domain protein; KEGG: ate:Athe_1860 glycoside hydrolase family 48.
 
    0.828
Cthe_0275
PFAM: glycosyltransferase 36; carbohydrate binding; glycosyltransferase 36 associated; KEGG: cce:Ccel_2109 glycosyltransferase 36.
 
 
 0.778
Cthe_2989
PFAM: glycosyltransferase 36; KEGG: tnp:Tnap_0603 glycosyltransferase 36.
 
  
 0.742
bglB
PFAM: glycoside hydrolase family 3 domain protein; KEGG: ttr:Tter_0181 glycoside hydrolase family 3 domain protein; Belongs to the glycosyl hydrolase 3 family.
  
 
 0.684
Your Current Organism:
Hungateiclostridium thermocellum
NCBI taxonomy Id: 203119
Other names: Clostridium thermocellum ATCC 27405, H. thermocellum ATCC 27405, Hungateiclostridium thermocellum ATCC 27405, Ruminiclostridium thermocellum ATCC 27405
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