STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Cthe_0427Stage II sporulation protein E; KEGG: emi:Emin_0751 protein serine/threonine phosphatase; PFAM: Stage II sporulation protein E; SMART: protein phosphatase 2C domain protein. (389 aa)    
Predicted Functional Partners:
Cthe_0426
KEGG: emi:Emin_0752 putative PAS/PAC sensor protein; PFAM: Fe-S cluster domain protein; PAS fold domain protein; SMART: PAS domain containing protein.
 
    0.963
Cthe_0431
KEGG: emi:Emin_0753 hypothetical protein.
 
    0.956
Cthe_0425
KEGG: emi:Emin_0753 hypothetical protein.
 
    0.921
Cthe_1825
KEGG: gsu:GSU2314 sensory box histidine kinase/response regulator; PFAM: ATP-binding region ATPase domain protein; histidine kinase A domain protein; histidine kinase HAMP region domain protein; response regulator receiver; Hpt domain protein; SMART: ATP-binding region ATPase domain protein; histidine kinase A domain protein; response regulator receiver.
  
  
 0.858
rex
CoA-binding domain protein; Modulates transcription in response to changes in cellular NADH/NAD(+) redox state.
 
  
 0.844
Cthe_0429
NADH dehydrogenase (quinone); KEGG: cbk:CLL_A2308 putative iron hydrogenase, electron-transfer subunit; PFAM: Respiratory-chain NADH dehydrogenase domain 51 kDa subunit; Soluble ligand binding domain; NADH ubiquinone oxidoreductase, F subunit, iron sulphur binding.
  
    0.832
Cthe_0430
KEGG: cpy:Cphy_0087 hydrogenase, Fe-only; TIGRFAM: hydrogenase, Fe-only; PFAM: hydrogenase large subunit domain protein; NADH:ubiquinone oxidoreductase, subunit G, iron-sulphur binding; ferredoxin; iron hydrogenase small subunit.
 
    0.813
Cthe_0428
PFAM: NADH dehydrogenase (ubiquinone) 24 kDa subunit; KEGG: cpy:Cphy_0089 NADH dehydrogenase (ubiquinone) 24 kDa subunit.
  
    0.798
Cthe_0424
PFAM: aminoglycoside phosphotransferase; KEGG: emi:Emin_0754 aminoglycoside phosphotransferase.
 
    0.743
Cthe_0423
PFAM: iron-containing alcohol dehydrogenase; Aldehyde Dehydrogenase; KEGG: emi:Emin_0755 bifunctional acetaldehyde-CoA/alcohol dehydrogenase; In the C-terminal section; belongs to the iron-containing alcohol dehydrogenase family.
 
    0.736
Your Current Organism:
Hungateiclostridium thermocellum
NCBI taxonomy Id: 203119
Other names: Clostridium thermocellum ATCC 27405, H. thermocellum ATCC 27405, Hungateiclostridium thermocellum ATCC 27405, Ruminiclostridium thermocellum ATCC 27405
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