node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
Cthe_0597 | Cthe_0599 | Cthe_0597 | Cthe_0599 | KEGG: pth:PTH_0639 sulfur transfer protein; TIGRFAM: thiamine biosynthesis protein ThiS; PFAM: thiamineS protein. | KEGG: dae:Dtox_1681 thiazole biosynthesis protein ThiH; TIGRFAM: thiazole biosynthesis protein ThiH; PFAM: biotin and thiamin synthesis associated; Radical SAM domain protein. | 0.799 |
Cthe_0597 | Cthe_0600 | Cthe_0597 | Cthe_0600 | KEGG: pth:PTH_0639 sulfur transfer protein; TIGRFAM: thiamine biosynthesis protein ThiS; PFAM: thiamineS protein. | KEGG: pth:PTH_0642 thiamine biosynthesis protein ThiF; TIGRFAM: thiamine biosynthesis protein ThiF; PFAM: UBA/THIF-type NAD/FAD binding protein. | 0.992 |
Cthe_0597 | Cthe_0654 | Cthe_0597 | Cthe_0654 | KEGG: pth:PTH_0639 sulfur transfer protein; TIGRFAM: thiamine biosynthesis protein ThiS; PFAM: thiamineS protein. | KEGG: amt:Amet_4105 thiamine biosynthesis protein ThiH; PFAM: biotin and thiamin synthesis associated; Radical SAM domain protein; SMART: Elongator protein 3/MiaB/NifB. | 0.568 |
Cthe_0597 | Cthe_2538 | Cthe_0597 | Cthe_2538 | KEGG: pth:PTH_0639 sulfur transfer protein; TIGRFAM: thiamine biosynthesis protein ThiS; PFAM: thiamineS protein. | KEGG: dhd:Dhaf_4110 thiamine biosynthesis protein ThiS; TIGRFAM: thiamine biosynthesis protein ThiS; PFAM: thiamineS protein. | 0.900 |
Cthe_0597 | Cthe_2539 | Cthe_0597 | Cthe_2539 | KEGG: pth:PTH_0639 sulfur transfer protein; TIGRFAM: thiamine biosynthesis protein ThiS; PFAM: thiamineS protein. | PFAM: UBA/THIF-type NAD/FAD binding protein; MoeZ/MoeB domain protein; KEGG: dhd:Dhaf_4109 UBA/ThiF-type NAD/FAD binding protein. | 0.828 |
Cthe_0597 | thiC | Cthe_0597 | Cthe_0602 | KEGG: pth:PTH_0639 sulfur transfer protein; TIGRFAM: thiamine biosynthesis protein ThiS; PFAM: thiamineS protein. | Thiamine biosynthesis protein ThiC; Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction. Belongs to the ThiC family. | 0.879 |
Cthe_0597 | thiE | Cthe_0597 | Cthe_0601 | KEGG: pth:PTH_0639 sulfur transfer protein; TIGRFAM: thiamine biosynthesis protein ThiS; PFAM: thiamineS protein. | Thiamine-phosphate pyrophosphorylase; Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP). Belongs to the thiamine-phosphate synthase family. | 0.912 |
Cthe_0597 | thiG | Cthe_0597 | Cthe_0598 | KEGG: pth:PTH_0639 sulfur transfer protein; TIGRFAM: thiamine biosynthesis protein ThiS; PFAM: thiamineS protein. | Thiazole biosynthesis family protein; Catalyzes the rearrangement of 1-deoxy-D-xylulose 5-phosphate (DXP) to produce the thiazole phosphate moiety of thiamine. Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS. In vitro, sulfur can be provided by H(2)S. | 0.997 |
Cthe_0599 | Cthe_0597 | Cthe_0599 | Cthe_0597 | KEGG: dae:Dtox_1681 thiazole biosynthesis protein ThiH; TIGRFAM: thiazole biosynthesis protein ThiH; PFAM: biotin and thiamin synthesis associated; Radical SAM domain protein. | KEGG: pth:PTH_0639 sulfur transfer protein; TIGRFAM: thiamine biosynthesis protein ThiS; PFAM: thiamineS protein. | 0.799 |
Cthe_0599 | Cthe_0600 | Cthe_0599 | Cthe_0600 | KEGG: dae:Dtox_1681 thiazole biosynthesis protein ThiH; TIGRFAM: thiazole biosynthesis protein ThiH; PFAM: biotin and thiamin synthesis associated; Radical SAM domain protein. | KEGG: pth:PTH_0642 thiamine biosynthesis protein ThiF; TIGRFAM: thiamine biosynthesis protein ThiF; PFAM: UBA/THIF-type NAD/FAD binding protein. | 0.888 |
Cthe_0599 | Cthe_0654 | Cthe_0599 | Cthe_0654 | KEGG: dae:Dtox_1681 thiazole biosynthesis protein ThiH; TIGRFAM: thiazole biosynthesis protein ThiH; PFAM: biotin and thiamin synthesis associated; Radical SAM domain protein. | KEGG: amt:Amet_4105 thiamine biosynthesis protein ThiH; PFAM: biotin and thiamin synthesis associated; Radical SAM domain protein; SMART: Elongator protein 3/MiaB/NifB. | 0.919 |
Cthe_0599 | Cthe_2538 | Cthe_0599 | Cthe_2538 | KEGG: dae:Dtox_1681 thiazole biosynthesis protein ThiH; TIGRFAM: thiazole biosynthesis protein ThiH; PFAM: biotin and thiamin synthesis associated; Radical SAM domain protein. | KEGG: dhd:Dhaf_4110 thiamine biosynthesis protein ThiS; TIGRFAM: thiamine biosynthesis protein ThiS; PFAM: thiamineS protein. | 0.523 |
Cthe_0599 | Cthe_2539 | Cthe_0599 | Cthe_2539 | KEGG: dae:Dtox_1681 thiazole biosynthesis protein ThiH; TIGRFAM: thiazole biosynthesis protein ThiH; PFAM: biotin and thiamin synthesis associated; Radical SAM domain protein. | PFAM: UBA/THIF-type NAD/FAD binding protein; MoeZ/MoeB domain protein; KEGG: dhd:Dhaf_4109 UBA/ThiF-type NAD/FAD binding protein. | 0.532 |
Cthe_0599 | thiC | Cthe_0599 | Cthe_0602 | KEGG: dae:Dtox_1681 thiazole biosynthesis protein ThiH; TIGRFAM: thiazole biosynthesis protein ThiH; PFAM: biotin and thiamin synthesis associated; Radical SAM domain protein. | Thiamine biosynthesis protein ThiC; Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction. Belongs to the ThiC family. | 0.967 |
Cthe_0599 | thiE | Cthe_0599 | Cthe_0601 | KEGG: dae:Dtox_1681 thiazole biosynthesis protein ThiH; TIGRFAM: thiazole biosynthesis protein ThiH; PFAM: biotin and thiamin synthesis associated; Radical SAM domain protein. | Thiamine-phosphate pyrophosphorylase; Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP). Belongs to the thiamine-phosphate synthase family. | 0.949 |
Cthe_0599 | thiG | Cthe_0599 | Cthe_0598 | KEGG: dae:Dtox_1681 thiazole biosynthesis protein ThiH; TIGRFAM: thiazole biosynthesis protein ThiH; PFAM: biotin and thiamin synthesis associated; Radical SAM domain protein. | Thiazole biosynthesis family protein; Catalyzes the rearrangement of 1-deoxy-D-xylulose 5-phosphate (DXP) to produce the thiazole phosphate moiety of thiamine. Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS. In vitro, sulfur can be provided by H(2)S. | 0.999 |
Cthe_0600 | Cthe_0597 | Cthe_0600 | Cthe_0597 | KEGG: pth:PTH_0642 thiamine biosynthesis protein ThiF; TIGRFAM: thiamine biosynthesis protein ThiF; PFAM: UBA/THIF-type NAD/FAD binding protein. | KEGG: pth:PTH_0639 sulfur transfer protein; TIGRFAM: thiamine biosynthesis protein ThiS; PFAM: thiamineS protein. | 0.992 |
Cthe_0600 | Cthe_0599 | Cthe_0600 | Cthe_0599 | KEGG: pth:PTH_0642 thiamine biosynthesis protein ThiF; TIGRFAM: thiamine biosynthesis protein ThiF; PFAM: UBA/THIF-type NAD/FAD binding protein. | KEGG: dae:Dtox_1681 thiazole biosynthesis protein ThiH; TIGRFAM: thiazole biosynthesis protein ThiH; PFAM: biotin and thiamin synthesis associated; Radical SAM domain protein. | 0.888 |
Cthe_0600 | Cthe_0654 | Cthe_0600 | Cthe_0654 | KEGG: pth:PTH_0642 thiamine biosynthesis protein ThiF; TIGRFAM: thiamine biosynthesis protein ThiF; PFAM: UBA/THIF-type NAD/FAD binding protein. | KEGG: amt:Amet_4105 thiamine biosynthesis protein ThiH; PFAM: biotin and thiamin synthesis associated; Radical SAM domain protein; SMART: Elongator protein 3/MiaB/NifB. | 0.461 |
Cthe_0600 | Cthe_2538 | Cthe_0600 | Cthe_2538 | KEGG: pth:PTH_0642 thiamine biosynthesis protein ThiF; TIGRFAM: thiamine biosynthesis protein ThiF; PFAM: UBA/THIF-type NAD/FAD binding protein. | KEGG: dhd:Dhaf_4110 thiamine biosynthesis protein ThiS; TIGRFAM: thiamine biosynthesis protein ThiS; PFAM: thiamineS protein. | 0.982 |