STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Cthe_0635KEGG: bsu:BSU15760 phosphorylated protein phosphatase; PFAM: Protein phosphatase 2C-like; SMART: protein phosphatase 2C domain protein. (276 aa)    
Predicted Functional Partners:
Cthe_0574
KEGG: cce:Ccel_1535 serine/threonine protein kinase with PASTA sensor(s); PFAM: Serine/threonine-protein kinase-like domain; PASTA domain containing protein; SMART: serine/threonine protein kinase; Tyrosine-protein kinase, catalytic domain; PASTA domain containing protein.
 
 0.974
Cthe_0634
KEGG: cac:CAC3039 hypothetical protein; PFAM: Serine/threonine-protein kinase-like domain; SMART: serine/threonine protein kinase; Tyrosine-protein kinase, catalytic domain.
 
 
 0.947
Cthe_1136
PFAM: Serine/threonine-protein kinase-like domain; Tetratricopeptide TPR_1 repeat-containing protein; KEGG: cyn:Cyan7425_5270 serine/threonine protein kinase.
 
 
 0.860
Cthe_0571
Sun protein; Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA.
  
  
 0.773
Cthe_0979
KEGG: cce:Ccel_0478 penicillin-binding protein transpeptidase; PFAM: penicillin-binding protein transpeptidase; Penicillin-binding protein dimerisation domain; PASTA domain containing protein; SMART: PASTA domain containing protein.
 
 
 0.683
fmt
methionyl-tRNA formyltransferase; Attaches a formyl group to the free amino group of methionyl- tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus; Belongs to the Fmt family.
  
   0.652
Cthe_3045
KEGG: aoe:Clos_2578 FHA domain-containing protein; PFAM: Forkhead-associated protein; SMART: Forkhead-associated protein.
 
 
 0.619
Cthe_0636
KEGG: cac:CAC0409 hypothetical protein.
  
    0.576
dnaJ
Chaperone protein DnaJ; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, D [...]
  
   0.566
Cthe_2224
KEGG: gfo:GFO_2018 methionyl-tRNA formyltransferase.
  
   0.534
Your Current Organism:
Hungateiclostridium thermocellum
NCBI taxonomy Id: 203119
Other names: Clostridium thermocellum ATCC 27405, H. thermocellum ATCC 27405, Hungateiclostridium thermocellum ATCC 27405, Ruminiclostridium thermocellum ATCC 27405
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.