STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Cthe_0798PFAM: lipolytic protein G-D-S-L family; Dockerin type 1; KEGG: ricin B lectin. (528 aa)    
Predicted Functional Partners:
cipA
Cellulosome anchoring protein cohesin region; Acts as a scaffolding protein in the cellulosome. It promotes binding of cellulose to the catalytic domains of the cellulolytic enzymes.
  
 
 0.824
Cthe_1235
KEGG: pjd:Pjdr2_1173 S-layer domain protein; PFAM: PKD domain containing protein; Fibronectin type III domain protein; Cna B domain protein; Hyalin; S-layer domain-containing protein; SMART: PKD domain containing protein; Fibronectin type III domain protein.
  
   0.813
Cthe_0135
PFAM: Acyl transferase; Beta-ketoacyl synthase; phosphopantetheine-binding; KR domain protein; KEGG: sus:Acid_3077 beta-ketoacyl synthase.
 
  
 0.811
Cthe_1911
KEGG: cce:Ccel_1656 carbohydrate binding family 6; PFAM: Carbohydrate binding family 6; S-layer domain-containing protein; SMART: cellulose binding type IV.
 
   
 0.781
Cthe_1257
Carbohydrate-binding CenC domain protein; KEGG: csc:Csac_1076 glycoside hydrolase family protein; PFAM: Carbohydrate-binding CenC domain protein; type 3a cellulose-binding domain protein; SMART: von Willebrand factor type A.
  
    0.766
rsgI5
alpha-L-arabinofuranosidase B; Anti-sigma factor for SigI5. Negatively regulates SigI5 activity through direct interaction. Binding of the polysaccharide substrate to the extracellular C-terminal sensing domain of RsgI5 may induce a conformational change in its N-terminal cytoplasmic region, leading to the release and activation of SigI5.
  
   
 0.765
Cthe_1806
SMART: Ig domain protein group 2 domain protein; KEGG: cce:Ccel_1547 S-layer domain protein.
 
    0.765
Cthe_2353
PFAM: Ig domain protein group 1 domain protein; KEGG: alv:Alvin_3300 lipase, class 2.
  
   
 0.716
Cthe_0251
PFAM: transglutaminase domain-containing protein; KEGG: afu:AF2400 hypothetical protein.
 
   
 0.708
Cthe_3079
PFAM: cellulosome anchoring protein cohesin region; S-layer domain-containing protein; KEGG: lsp:Bsph_2088 cell surface glycoprotein 2 precursor (S-layer protein 2).
  
 
 0.672
Your Current Organism:
Hungateiclostridium thermocellum
NCBI taxonomy Id: 203119
Other names: Clostridium thermocellum ATCC 27405, H. thermocellum ATCC 27405, Hungateiclostridium thermocellum ATCC 27405, Ruminiclostridium thermocellum ATCC 27405
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