node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
Cthe_0784 | carA | Cthe_0784 | Cthe_0950 | KEGG: cce:Ccel_0620 hypothetical protein. | KEGG: cce:Ccel_0615 carbamoyl-phosphate synthase, small subunit; TIGRFAM: carbamoyl-phosphate synthase, small subunit; PFAM: Carbamoyl-phosphate synthase small chain; glutamine amidotransferase class-I; Belongs to the CarA family. | 0.801 |
Cthe_0784 | carA-2 | Cthe_0784 | Cthe_1867 | KEGG: cce:Ccel_0620 hypothetical protein. | KEGG: cce:Ccel_2913 carbamoyl-phosphate synthase, small subunit; TIGRFAM: carbamoyl-phosphate synthase, small subunit; PFAM: Carbamoyl-phosphate synthase small chain; glutamine amidotransferase class-I; Belongs to the CarA family. | 0.801 |
Cthe_0784 | carB | Cthe_0784 | Cthe_0949 | KEGG: cce:Ccel_0620 hypothetical protein. | KEGG: cce:Ccel_0616 carbamoyl-phosphate synthase, large subunit; TIGRFAM: carbamoyl-phosphate synthase, large subunit; PFAM: Carbamoyl-phosphate synthase L chain ATP-binding; Carbamoyl-phosphate synthetase large chain domain protein; Carbamoyl-phosphate synthetase large chain oligomerisation; MGS domain protein; Belongs to the CarB family. | 0.877 |
Cthe_0784 | carB-2 | Cthe_0784 | Cthe_1868 | KEGG: cce:Ccel_0620 hypothetical protein. | KEGG: cce:Ccel_2914 carbamoyl-phosphate synthase, large subunit; TIGRFAM: carbamoyl-phosphate synthase, large subunit; PFAM: Carbamoyl-phosphate synthase L chain ATP-binding; Carbamoyl-phosphate synthetase large chain domain protein; Carbamoyl-phosphate synthetase large chain oligomerisation; MGS domain protein; Belongs to the CarB family. | 0.819 |
Cthe_0784 | pyrB | Cthe_0784 | Cthe_0953 | KEGG: cce:Ccel_0620 hypothetical protein. | TIGRFAM: aspartate carbamoyltransferase; KEGG: cce:Ccel_0612 aspartate carbamoyltransferase; PFAM: aspartate/ornithine carbamoyltransferase carbamoyl-P binding domain; aspartate/ornithine carbamoyltransferase Asp/Orn-binding region; Belongs to the aspartate/ornithine carbamoyltransferase superfamily. ATCase family. | 0.960 |
Cthe_0784 | pyrC | Cthe_0784 | Cthe_0952 | KEGG: cce:Ccel_0620 hypothetical protein. | Dihydroorotase, multifunctional complex type; Catalyzes the reversible cyclization of carbamoyl aspartate to dihydroorotate; Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily. | 0.960 |
Cthe_0784 | pyrD | Cthe_0784 | Cthe_0947 | KEGG: cce:Ccel_0620 hypothetical protein. | Dihydroorotate dehydrogenase family protein; Catalyzes the conversion of dihydroorotate to orotate. | 0.962 |
Cthe_0784 | pyrF | Cthe_0784 | Cthe_0951 | KEGG: cce:Ccel_0620 hypothetical protein. | TIGRFAM: orotidine 5'-phosphate decarboxylase; KEGG: cce:Ccel_0614 orotidine 5'-phosphate decarboxylase; PFAM: Orotidine 5'-phosphate decarboxylase; Belongs to the OMP decarboxylase family. Type 2 subfamily. | 0.979 |
Cthe_0784 | pyrK | Cthe_0784 | Cthe_0948 | KEGG: cce:Ccel_0620 hypothetical protein. | Dihydroorotate dehydrogenase B (NAD(+)), electron transfer subunit; Responsible for channeling the electrons from the oxidation of dihydroorotate from the FMN redox center in the PyrD type B subunit to the ultimate electron acceptor NAD(+). | 0.896 |
Cthe_0784 | pyrR | Cthe_0784 | Cthe_0954 | KEGG: cce:Ccel_0620 hypothetical protein. | Phosphoribosyltransferase; Regulates transcriptional attenuation of the pyrimidine nucleotide (pyr) operon by binding in a uridine-dependent manner to specific sites on pyr mRNA. This disrupts an antiterminator hairpin in the RNA and favors formation of a downstream transcription terminator, leading to a reduced expression of downstream genes. Belongs to the purine/pyrimidine phosphoribosyltransferase family. PyrR subfamily. | 0.876 |
carA | Cthe_0784 | Cthe_0950 | Cthe_0784 | KEGG: cce:Ccel_0615 carbamoyl-phosphate synthase, small subunit; TIGRFAM: carbamoyl-phosphate synthase, small subunit; PFAM: Carbamoyl-phosphate synthase small chain; glutamine amidotransferase class-I; Belongs to the CarA family. | KEGG: cce:Ccel_0620 hypothetical protein. | 0.801 |
carA | carA-2 | Cthe_0950 | Cthe_1867 | KEGG: cce:Ccel_0615 carbamoyl-phosphate synthase, small subunit; TIGRFAM: carbamoyl-phosphate synthase, small subunit; PFAM: Carbamoyl-phosphate synthase small chain; glutamine amidotransferase class-I; Belongs to the CarA family. | KEGG: cce:Ccel_2913 carbamoyl-phosphate synthase, small subunit; TIGRFAM: carbamoyl-phosphate synthase, small subunit; PFAM: Carbamoyl-phosphate synthase small chain; glutamine amidotransferase class-I; Belongs to the CarA family. | 0.906 |
carA | carB | Cthe_0950 | Cthe_0949 | KEGG: cce:Ccel_0615 carbamoyl-phosphate synthase, small subunit; TIGRFAM: carbamoyl-phosphate synthase, small subunit; PFAM: Carbamoyl-phosphate synthase small chain; glutamine amidotransferase class-I; Belongs to the CarA family. | KEGG: cce:Ccel_0616 carbamoyl-phosphate synthase, large subunit; TIGRFAM: carbamoyl-phosphate synthase, large subunit; PFAM: Carbamoyl-phosphate synthase L chain ATP-binding; Carbamoyl-phosphate synthetase large chain domain protein; Carbamoyl-phosphate synthetase large chain oligomerisation; MGS domain protein; Belongs to the CarB family. | 0.999 |
carA | carB-2 | Cthe_0950 | Cthe_1868 | KEGG: cce:Ccel_0615 carbamoyl-phosphate synthase, small subunit; TIGRFAM: carbamoyl-phosphate synthase, small subunit; PFAM: Carbamoyl-phosphate synthase small chain; glutamine amidotransferase class-I; Belongs to the CarA family. | KEGG: cce:Ccel_2914 carbamoyl-phosphate synthase, large subunit; TIGRFAM: carbamoyl-phosphate synthase, large subunit; PFAM: Carbamoyl-phosphate synthase L chain ATP-binding; Carbamoyl-phosphate synthetase large chain domain protein; Carbamoyl-phosphate synthetase large chain oligomerisation; MGS domain protein; Belongs to the CarB family. | 0.999 |
carA | pyrB | Cthe_0950 | Cthe_0953 | KEGG: cce:Ccel_0615 carbamoyl-phosphate synthase, small subunit; TIGRFAM: carbamoyl-phosphate synthase, small subunit; PFAM: Carbamoyl-phosphate synthase small chain; glutamine amidotransferase class-I; Belongs to the CarA family. | TIGRFAM: aspartate carbamoyltransferase; KEGG: cce:Ccel_0612 aspartate carbamoyltransferase; PFAM: aspartate/ornithine carbamoyltransferase carbamoyl-P binding domain; aspartate/ornithine carbamoyltransferase Asp/Orn-binding region; Belongs to the aspartate/ornithine carbamoyltransferase superfamily. ATCase family. | 0.998 |
carA | pyrC | Cthe_0950 | Cthe_0952 | KEGG: cce:Ccel_0615 carbamoyl-phosphate synthase, small subunit; TIGRFAM: carbamoyl-phosphate synthase, small subunit; PFAM: Carbamoyl-phosphate synthase small chain; glutamine amidotransferase class-I; Belongs to the CarA family. | Dihydroorotase, multifunctional complex type; Catalyzes the reversible cyclization of carbamoyl aspartate to dihydroorotate; Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily. | 0.990 |
carA | pyrD | Cthe_0950 | Cthe_0947 | KEGG: cce:Ccel_0615 carbamoyl-phosphate synthase, small subunit; TIGRFAM: carbamoyl-phosphate synthase, small subunit; PFAM: Carbamoyl-phosphate synthase small chain; glutamine amidotransferase class-I; Belongs to the CarA family. | Dihydroorotate dehydrogenase family protein; Catalyzes the conversion of dihydroorotate to orotate. | 0.915 |
carA | pyrF | Cthe_0950 | Cthe_0951 | KEGG: cce:Ccel_0615 carbamoyl-phosphate synthase, small subunit; TIGRFAM: carbamoyl-phosphate synthase, small subunit; PFAM: Carbamoyl-phosphate synthase small chain; glutamine amidotransferase class-I; Belongs to the CarA family. | TIGRFAM: orotidine 5'-phosphate decarboxylase; KEGG: cce:Ccel_0614 orotidine 5'-phosphate decarboxylase; PFAM: Orotidine 5'-phosphate decarboxylase; Belongs to the OMP decarboxylase family. Type 2 subfamily. | 0.949 |
carA | pyrK | Cthe_0950 | Cthe_0948 | KEGG: cce:Ccel_0615 carbamoyl-phosphate synthase, small subunit; TIGRFAM: carbamoyl-phosphate synthase, small subunit; PFAM: Carbamoyl-phosphate synthase small chain; glutamine amidotransferase class-I; Belongs to the CarA family. | Dihydroorotate dehydrogenase B (NAD(+)), electron transfer subunit; Responsible for channeling the electrons from the oxidation of dihydroorotate from the FMN redox center in the PyrD type B subunit to the ultimate electron acceptor NAD(+). | 0.898 |
carA | pyrR | Cthe_0950 | Cthe_0954 | KEGG: cce:Ccel_0615 carbamoyl-phosphate synthase, small subunit; TIGRFAM: carbamoyl-phosphate synthase, small subunit; PFAM: Carbamoyl-phosphate synthase small chain; glutamine amidotransferase class-I; Belongs to the CarA family. | Phosphoribosyltransferase; Regulates transcriptional attenuation of the pyrimidine nucleotide (pyr) operon by binding in a uridine-dependent manner to specific sites on pyr mRNA. This disrupts an antiterminator hairpin in the RNA and favors formation of a downstream transcription terminator, leading to a reduced expression of downstream genes. Belongs to the purine/pyrimidine phosphoribosyltransferase family. PyrR subfamily. | 0.792 |