STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
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Gene Fusion
Cooccurrence
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Experiments
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[Homology]
Score
celSGlycoside hydrolase family 48; This enzyme catalyzes the exohydrolysis of 1,4-beta- glucosidic linkages in cellulose with a preference for amorphous or crystalline cellulose over carboxymethyl cellulose. (741 aa)    
Predicted Functional Partners:
cipA
Cellulosome anchoring protein cohesin region; Acts as a scaffolding protein in the cellulosome. It promotes binding of cellulose to the catalytic domains of the cellulolytic enzymes.
  
 
 0.987
celI
Glycoside hydrolase family 9; This enzyme catalyzes the endohydrolysis of 1,4-beta- glucosidic linkages in cellulose, lichenin and cereal beta-D-glucans. Principally active against barley beta-glucan; Belongs to the glycosyl hydrolase 9 (cellulase E) family.
 
   0.979
Cthe_0271
PFAM: type 3a cellulose-binding domain protein; KEGG: ate:Athe_1860 glycoside hydrolase family 48.
 
  
 0.975
celF
Glycoside hydrolase family 9; This enzyme catalyzes the endohydrolysis of 1,4-beta- glucosidic linkages in cellulose, lichenin and cereal beta-D-glucans.
 
0.957
Cthe_0578
PFAM: glycoside hydrolase family 9; type 3a cellulose-binding domain protein; Dockerin type 1; KEGG: ate:Athe_1867 glycoside hydrolase family 48; Belongs to the glycosyl hydrolase 9 (cellulase E) family.
  
0.920
Cthe_0745
PFAM: glycoside hydrolase family 9; type 3a cellulose-binding domain protein; Dockerin type 1; KEGG: cce:Ccel_0731 glycoside hydrolase family 9; Belongs to the glycosyl hydrolase 9 (cellulase E) family.
  
0.914
Cthe_0625
PFAM: glycoside hydrolase family 9; type 3a cellulose-binding domain protein; Dockerin type 1; KEGG: ate:Athe_1867 glycoside hydrolase family 48; Belongs to the glycosyl hydrolase 9 (cellulase E) family.
  
0.899
rsgI4
Type 3a cellulose-binding domain protein; Anti-sigma factor for SigI4. Negatively regulates SigI4 activity through direct interaction. Binding of the polysaccharide substrate to the extracellular C-terminal sensing domain of RsgI4 may induce a conformational change in its N-terminal cytoplasmic region, leading to the release and activation of SigI4.
 
    0.884
Cthe_2812
PFAM: glycoside hydrolase family 9; Dockerin type 1; KEGG: cce:Ccel_0753 glycoside hydrolase family 9; Belongs to the glycosyl hydrolase 9 (cellulase E) family.
 
0.869
xghA
Dockerin type 1; Hydrolyzes the glucosidic bonds of unbranched Glc residues in tamarind seed xyloglucan, producing XXXG, XLXG, XXLG and XLLG. Has low activity on carboxymethylcellulose, lichenan,hydroxyethylcellulose and glucuronoxylan, and no activity on xylan, polygalaturonic acid, wheat arabinoxylan, rhamnogalacturan, curdlan, laminarin, galactomannan, galactan, arabinan and pachyman or amorphous cellulose (By similarity).
 
  
0.813
Your Current Organism:
Hungateiclostridium thermocellum
NCBI taxonomy Id: 203119
Other names: Clostridium thermocellum ATCC 27405, H. thermocellum ATCC 27405, Hungateiclostridium thermocellum ATCC 27405, Ruminiclostridium thermocellum ATCC 27405
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