STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Cthe_2193Carbohydrate binding family 6; KEGG: chu:CHU_2399 hypothetical protein; PFAM: Carbohydrate binding family 6; glycoside hydrolase family 5; Fibronectin type III domain protein; Dockerin type 1; SMART: cellulose binding type IV. (948 aa)    
Predicted Functional Partners:
celC
Glycoside hydrolase family 5; This enzyme catalyzes the endohydrolysis of 1,4-beta- glucosidic linkages in cellulose, lichenin and cereal beta-D-glucans.
  
   
 0.738
Cthe_2194
KEGG: cce:Ccel_1232 carbohydrate binding family 6; PFAM: Carbohydrate binding family 6; Dockerin type 1; esterase; SMART: cellulose binding type IV.
 
   
0.714
Cthe_0275
PFAM: glycosyltransferase 36; carbohydrate binding; glycosyltransferase 36 associated; KEGG: cce:Ccel_2109 glycosyltransferase 36.
  
  
 0.709
Cthe_2989
PFAM: glycosyltransferase 36; KEGG: tnp:Tnap_0603 glycosyltransferase 36.
  
 
 0.709
bglA
TIGRFAM: beta-galactosidase; KEGG: dtu:Dtur_1799 beta-galactosidase; PFAM: glycoside hydrolase family 1; Belongs to the glycosyl hydrolase 1 family.
   
 
  0.653
bglB
PFAM: glycoside hydrolase family 3 domain protein; KEGG: ttr:Tter_0181 glycoside hydrolase family 3 domain protein; Belongs to the glycosyl hydrolase 3 family.
    
  0.651
Cthe_1428
Beta-glucosidase; KEGG: hor:Hore_04820 beta-glucosidase; PFAM: glycoside hydrolase family 1; Belongs to the glycosyl hydrolase 1 family.
     
  0.650
cipA
Cellulosome anchoring protein cohesin region; Acts as a scaffolding protein in the cellulosome. It promotes binding of cellulose to the catalytic domains of the cellulolytic enzymes.
  
   
 0.554
Cthe_0438
PFAM: Dockerin type 1; KEGG: cce:Ccel_2162 lipolytic protein G-D-S-L family.
      
 0.529
Cthe_2195
KEGG: cce:Ccel_1656 carbohydrate binding family 6; PFAM: Carbohydrate binding family 6; Dockerin type 1; SMART: cellulose binding type IV; Parallel beta-helix repeat.
 
    
0.526
Your Current Organism:
Hungateiclostridium thermocellum
NCBI taxonomy Id: 203119
Other names: Clostridium thermocellum ATCC 27405, H. thermocellum ATCC 27405, Hungateiclostridium thermocellum ATCC 27405, Ruminiclostridium thermocellum ATCC 27405
Server load: low (34%) [HD]