STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Cthe_2449KEGG: eel:EUBELI_00289 phosphoglycerate mutase; PFAM: Phosphoglycerate mutase; SMART: Phosphoglycerate mutase; Belongs to the phosphoglycerate mutase family. (204 aa)    
Predicted Functional Partners:
Cthe_2448
PFAM: inner-membrane translocator; KEGG: oih:OB2573 ribose ABC transporter permease; Belongs to the binding-protein-dependent transport system permease family.
  
    0.807
Cthe_2447
ABC transporter related protein; KEGG: dth:DICTH_0297 ribose transport ATP-binding protein RbsA; PFAM: ABC transporter related; SMART: AAA ATPase.
  
  
 0.766
Cthe_2446
Hypothetical protein; KEGG: rcu:RCOM_2001640 D-allose-binding periplasmic protein precursor, putative.
  
    0.737
msrA
Peptide methionine sulfoxide reductase; Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine.
 
   0.634
Cthe_3116
TIGRFAM: mannose-6-phosphate isomerase, class I; KEGG: cce:Ccel_1179 mannose-6-phosphate isomerase, class I; PFAM: mannose-6-phosphate isomerase type I.
   
  
 0.614
gpmI
Phosphoglycerate mutase, 2,3-bisphosphoglycerate-independent; Catalyzes the interconversion of 2-phosphoglycerate and 3- phosphoglycerate.
   
  
 0.585
pfp
Phosphofructokinase; Catalyzes the phosphorylation of D-fructose 6-phosphate, the first committing step of glycolysis. Uses inorganic phosphate (PPi) as phosphoryl donor instead of ATP like common ATP-dependent phosphofructokinases (ATP-PFKs), which renders the reaction reversible, and can thus function both in glycolysis and gluconeogenesis. Consistently, PPi-PFK can replace the enzymes of both the forward (ATP- PFK) and reverse (fructose-bisphosphatase (FBPase)) reactions.
   
 
 0.568
Cthe_0349
TIGRFAM: fructose-1,6-bisphosphate aldolase, class II; ketose-bisphosphate aldolase; KEGG: cce:Ccel_2222 fructose-1,6-bisphosphate aldolase, class II; PFAM: ketose-bisphosphate aldolase class-II.
     
 0.568
Cthe_2276
AAA ATPase central domain protein; KEGG: amt:Amet_3170 ATP-dependent metalloprotease FtsH; PFAM: AAA ATPase central domain protein; SMART: AAA ATPase; Belongs to the AAA ATPase family.
    
 
 0.562
cobS
Cobalamin 5'-phosphate synthase; Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin). Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'- phosphate; Belongs to the CobS family.
 
  
 0.562
Your Current Organism:
Hungateiclostridium thermocellum
NCBI taxonomy Id: 203119
Other names: Clostridium thermocellum ATCC 27405, H. thermocellum ATCC 27405, Hungateiclostridium thermocellum ATCC 27405, Ruminiclostridium thermocellum ATCC 27405
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