STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Cthe_2767PFAM: Methyltransferase type 12; KEGG: ana:alr3730 hypothetical protein. (465 aa)    
Predicted Functional Partners:
Cthe_2768
PFAM: metallophosphoesterase; KEGG: aba:Acid345_1977 metallophosphoesterase.
   0.999
Cthe_2764
PFAM: TROVE domain-containing protein; KEGG: cbe:Cbei_3557 TROVE domain-containing protein.
 
     0.823
Cthe_0028
KEGG: cby:CLM_2617 hypothetical protein.
 
     0.715
Cthe_0135
PFAM: Acyl transferase; Beta-ketoacyl synthase; phosphopantetheine-binding; KR domain protein; KEGG: sus:Acid_3077 beta-ketoacyl synthase.
  
 
 0.634
Cthe_1904
KEGG: hau:Haur_3129 amino acid adenylation domain-containing protein; TIGRFAM: amino acid adenylation domain protein; PFAM: AMP-dependent synthetase and ligase; major facilitator superfamily MFS_1; condensation domain protein; Thioesterase; phosphopantetheine-binding; Belongs to the ATP-dependent AMP-binding enzyme family.
 
 
 
 0.535
Cthe_2765
KEGG: bbe:BBR47_03130 hypothetical protein.
  
    0.504
Cthe_2766
KEGG: cai:Caci_3518 hypothetical protein.
       0.497
Cthe_1461
PFAM: FAD dependent oxidoreductase; Rieske [2Fe-2S] iron-sulphur domain; KEGG: amt:Amet_4663 FAD dependent oxidoreductase.
  
 
 0.460
tmcAL
Protein of unknown function DUF795; Catalyzes the formation of N(4)-acetylcytidine (ac(4)C) at the wobble position of elongator tRNA(Met), using acetate and ATP as substrates. First activates an acetate ion to form acetyladenylate (Ac- AMP) and then transfers the acetyl group to tRNA to form ac(4)C34.
  
    0.455
Cthe_2664
PFAM: ABC-1 domain-containing protein; KEGG: ckr:CKR_3068 hypothetical protein.
   
 
 0.441
Your Current Organism:
Hungateiclostridium thermocellum
NCBI taxonomy Id: 203119
Other names: Clostridium thermocellum ATCC 27405, H. thermocellum ATCC 27405, Hungateiclostridium thermocellum ATCC 27405, Ruminiclostridium thermocellum ATCC 27405
Server load: high (84%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.