STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Cthe_2945KEGG: cce:Ccel_2145 histidine kinase; PFAM: ATP-binding region ATPase domain protein; SMART: ATP-binding region ATPase domain protein. (616 aa)    
Predicted Functional Partners:
Cthe_1826
KEGG: lic:LIC12058 histidine kinase response regulator hybrid protein; PFAM: response regulator receiver; ATP-binding region ATPase domain protein; SMART: response regulator receiver; ATP-binding region ATPase domain protein.
 
 
 0.948
Cthe_1825
KEGG: gsu:GSU2314 sensory box histidine kinase/response regulator; PFAM: ATP-binding region ATPase domain protein; histidine kinase A domain protein; histidine kinase HAMP region domain protein; response regulator receiver; Hpt domain protein; SMART: ATP-binding region ATPase domain protein; histidine kinase A domain protein; response regulator receiver.
 
 
 0.944
Cthe_0287
Multi-sensor hybrid histidine kinase; KEGG: cvi:CV_1579 two-component hybrid sensor and regulator; PFAM: ATP-binding region ATPase domain protein; response regulator receiver; histidine kinase A domain protein; GAF domain protein; SMART: ATP-binding region ATPase domain protein; histidine kinase A domain protein; response regulator receiver; GAF domain protein.
 
 
 0.918
Cthe_0806
Multi-sensor hybrid histidine kinase; TIGRFAM: PAS sensor protein; PFAM: ATP-binding region ATPase domain protein; histidine kinase A domain protein; PAS fold domain protein; response regulator receiver; KEGG: swo:Swol_1328 signal transduction histidine kinase-like protein; SMART: response regulator receiver; ATP-binding region ATPase domain protein; histidine kinase A domain protein; PAS domain containing protein; PAC repeat-containing protein.
 
 
 0.881
Cthe_0582
Multi-sensor signal transduction histidine kinase; TIGRFAM: PAS sensor protein; PFAM: ATP-binding region ATPase domain protein; PAS fold domain protein; histidine kinase A domain protein; KEGG: dal:Dalk_2282 PAS/PAC sensor signal transduction histidine kinase; SMART: ATP-binding region ATPase domain protein; histidine kinase A domain protein; PAS domain containing protein; PAC repeat-containing protein; GAF domain protein.
 
 
 
0.762
Cthe_0891
KEGG: cyn:Cyan7425_0749 response regulator receiver protein; PFAM: response regulator receiver; SMART: response regulator receiver.
 
 
 0.761
Cthe_2944
Integral membrane sensor signal transduction histidine kinase; KEGG: cce:Ccel_2145 histidine kinase; PFAM: ATP-binding region ATPase domain protein; SMART: ATP-binding region ATPase domain protein.
 
   
0.732
Cthe_0725
TIGRFAM: metal dependent phophohydrolase; PFAM: metal-dependent phosphohydrolase HD sub domain; response regulator receiver; KEGG: drt:Dret_0887 response regulator receiver modulated metal dependent phosphohydrolase; SMART: response regulator receiver; metal-dependent phosphohydrolase HD region.
 
 
 0.724
Cthe_1378
KEGG: drt:Dret_0887 response regulator receiver modulated metal dependent phosphohydrolase; PFAM: metal-dependent phosphohydrolase HD sub domain; response regulator receiver; SMART: metal-dependent phosphohydrolase HD region; response regulator receiver.
 
 
 0.718
Cthe_2333
KEGG: cce:Ccel_3394 two component transcriptional regulator, winged helix family; PFAM: response regulator receiver; transcriptional regulator domain-containing protein; SMART: response regulator receiver.
  
 
 0.715
Your Current Organism:
Hungateiclostridium thermocellum
NCBI taxonomy Id: 203119
Other names: Clostridium thermocellum ATCC 27405, H. thermocellum ATCC 27405, Hungateiclostridium thermocellum ATCC 27405, Ruminiclostridium thermocellum ATCC 27405
Server load: low (26%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.