STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
cipACellulosome anchoring protein cohesin region; Acts as a scaffolding protein in the cellulosome. It promotes binding of cellulose to the catalytic domains of the cellulolytic enzymes. (1853 aa)    
Predicted Functional Partners:
Cthe_1307
PFAM: cellulosome anchoring protein cohesin region; S-layer domain-containing protein; KEGG: hmo:HM1_0137 multidomain protein with S-layer homology region, glug motif, ig motif, I-set domain, pkd domain.
  
 
 0.995
celB
Glycoside hydrolase family 5; This enzyme catalyzes the endohydrolysis of 1,4-beta- glucosidic linkages in cellulose, lichenin and cereal beta-D-glucans; Belongs to the glycosyl hydrolase 5 (cellulase A) family.
  
 
 0.993
celD
Glycoside hydrolase family 9; This enzyme catalyzes the endohydrolysis of 1,4-beta- glucosidic linkages in cellulose, lichenin and cereal beta-D-glucans.
  
 
 0.989
Cthe_3079
PFAM: cellulosome anchoring protein cohesin region; S-layer domain-containing protein; KEGG: lsp:Bsph_2088 cell surface glycoprotein 2 precursor (S-layer protein 2).
 
 
 0.988
celS
Glycoside hydrolase family 48; This enzyme catalyzes the exohydrolysis of 1,4-beta- glucosidic linkages in cellulose with a preference for amorphous or crystalline cellulose over carboxymethyl cellulose.
  
 
 0.987
celG
Glycoside hydrolase family 5; This enzyme catalyzes the endohydrolysis of 1,4-beta- glucosidic linkages in cellulose, lichenin and cereal beta-D-glucans; Belongs to the glycosyl hydrolase 5 (cellulase A) family.
  
 
 0.964
Cthe_0912
Glycoside hydrolase family 10; KEGG: cpy:Cphy_0624 endo-1,4-beta-xylanase; PFAM: glycoside hydrolase family 10; Carbohydrate-binding CenC domain protein; Dockerin type 1; esterase; SMART: glycoside hydrolase family 10.
  
 
 0.954
celE
Glycoside hydrolase family 5; Multifunctional enzyme involved in the degradation of plant cell wall polysaccharides. Displays endoglucanase activity against carboxymethyl cellulose (CMC) and barley beta-glucan. Also catalyzes the deacetylation of acetylated birchwood xylan and glucomannan, with a preference for the latter, and of the synthetic substrate 4-nitrophenyl acetate (4-NPAc) ; In the C-terminal section; belongs to the carbohydrate esterase 2 (CE2) family.
  
 
 0.952
olpB
PFAM: cellulosome anchoring protein cohesin region; S-layer domain-containing protein; KEGG: lel:LELG_02536 hypothetical protein.
 
  
 0.949
xghA
Dockerin type 1; Hydrolyzes the glucosidic bonds of unbranched Glc residues in tamarind seed xyloglucan, producing XXXG, XLXG, XXLG and XLLG. Has low activity on carboxymethylcellulose, lichenan,hydroxyethylcellulose and glucuronoxylan, and no activity on xylan, polygalaturonic acid, wheat arabinoxylan, rhamnogalacturan, curdlan, laminarin, galactomannan, galactan, arabinan and pachyman or amorphous cellulose (By similarity).
  
 
 0.940
Your Current Organism:
Hungateiclostridium thermocellum
NCBI taxonomy Id: 203119
Other names: Clostridium thermocellum ATCC 27405, H. thermocellum ATCC 27405, Hungateiclostridium thermocellum ATCC 27405, Ruminiclostridium thermocellum ATCC 27405
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