STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Cthe_3104KEGG: cbi:CLJ_B1663 putative CoA-substrate-specific enzyme activase; TIGRFAM: CoA-substrate-specific enzyme activase; PFAM: ATPase BadF/BadG/BcrA/BcrD type. (256 aa)    
Predicted Functional Partners:
Cthe_3103
PFAM: 2-hydroxyglutaryl-CoA dehydratase D-component; KEGG: dae:Dtox_3625 2-hydroxyglutaryl-CoA dehydratase D-component.
 
 0.996
Cthe_0352
PFAM: Protein of unknown function DUF2229, CoA enzyme activase; KEGG: aoe:Clos_2152 hypothetical protein.
     0.842
Cthe_2272
KEGG: amt:Amet_1169 hypothetical protein.
     0.805
Cthe_0353
KEGG: cce:Ccel_2219 hypothetical protein.
   
 0.702
Cthe_2273
KEGG: amt:Amet_1170 hypothetical protein.
   
 0.608
queC
exsB protein; Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0)).
       0.575
Cthe_3106
PFAM: 6-pyruvoyl tetrahydropterin synthase and hypothetical protein; KEGG: tte:TTE2368 6-pyruvoyl-tetrahydropterin synthase.
       0.543
queE
Radical SAM domain protein; Catalyzes the complex heterocyclic radical-mediated conversion of 6-carboxy-5,6,7,8-tetrahydropterin (CPH4) to 7-carboxy-7- deazaguanine (CDG), a step common to the biosynthetic pathways of all 7-deazapurine-containing compounds.
       0.522
Your Current Organism:
Hungateiclostridium thermocellum
NCBI taxonomy Id: 203119
Other names: Clostridium thermocellum ATCC 27405, H. thermocellum ATCC 27405, Hungateiclostridium thermocellum ATCC 27405, Ruminiclostridium thermocellum ATCC 27405
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