node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
Sde_0661 | Sde_1308 | Sde_0661 | Sde_1308 | Malate dehydrogenase (oxaloacetate decarboxylating) (NADP+). | Pyruvate kinase; Belongs to the pyruvate kinase family. | 0.954 |
Sde_0661 | Sde_2543 | Sde_0661 | Sde_2543 | Malate dehydrogenase (oxaloacetate decarboxylating) (NADP+). | Acetolactate synthase, small subunit. | 0.827 |
Sde_0661 | Sde_2866 | Sde_0661 | Sde_2866 | Malate dehydrogenase (oxaloacetate decarboxylating) (NADP+). | D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding. | 0.917 |
Sde_0661 | leuA | Sde_0661 | Sde_2298 | Malate dehydrogenase (oxaloacetate decarboxylating) (NADP+). | 2-isopropylmalate synthase; Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3- hydroxy-4-methylpentanoate (2-isopropylmalate); Belongs to the alpha-IPM synthase/homocitrate synthase family. LeuA type 2 subfamily. | 0.823 |
Sde_0661 | leuA-2 | Sde_0661 | Sde_2523 | Malate dehydrogenase (oxaloacetate decarboxylating) (NADP+). | 2-isopropylmalate synthase; Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3- hydroxy-4-methylpentanoate (2-isopropylmalate); Belongs to the alpha-IPM synthase/homocitrate synthase family. LeuA type 1 subfamily. | 0.823 |
Sde_0661 | leuC | Sde_0661 | Sde_2086 | Malate dehydrogenase (oxaloacetate decarboxylating) (NADP+). | 3-isopropylmalate dehydratase, large subunit; Catalyzes the isomerization between 2-isopropylmalate and 3- isopropylmalate, via the formation of 2-isopropylmaleate. | 0.808 |
Sde_0661 | leuD | Sde_0661 | Sde_2085 | Malate dehydrogenase (oxaloacetate decarboxylating) (NADP+). | 3-isopropylmalate dehydratase, small subunit; Catalyzes the isomerization between 2-isopropylmalate and 3- isopropylmalate, via the formation of 2-isopropylmaleate. Belongs to the LeuD family. LeuD type 1 subfamily. | 0.823 |
Sde_1308 | Sde_0661 | Sde_1308 | Sde_0661 | Pyruvate kinase; Belongs to the pyruvate kinase family. | Malate dehydrogenase (oxaloacetate decarboxylating) (NADP+). | 0.954 |
Sde_1308 | Sde_2543 | Sde_1308 | Sde_2543 | Pyruvate kinase; Belongs to the pyruvate kinase family. | Acetolactate synthase, small subunit. | 0.800 |
Sde_1308 | Sde_2866 | Sde_1308 | Sde_2866 | Pyruvate kinase; Belongs to the pyruvate kinase family. | D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding. | 0.938 |
Sde_1308 | leuA | Sde_1308 | Sde_2298 | Pyruvate kinase; Belongs to the pyruvate kinase family. | 2-isopropylmalate synthase; Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3- hydroxy-4-methylpentanoate (2-isopropylmalate); Belongs to the alpha-IPM synthase/homocitrate synthase family. LeuA type 2 subfamily. | 0.820 |
Sde_1308 | leuA-2 | Sde_1308 | Sde_2523 | Pyruvate kinase; Belongs to the pyruvate kinase family. | 2-isopropylmalate synthase; Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3- hydroxy-4-methylpentanoate (2-isopropylmalate); Belongs to the alpha-IPM synthase/homocitrate synthase family. LeuA type 1 subfamily. | 0.820 |
Sde_1308 | leuC | Sde_1308 | Sde_2086 | Pyruvate kinase; Belongs to the pyruvate kinase family. | 3-isopropylmalate dehydratase, large subunit; Catalyzes the isomerization between 2-isopropylmalate and 3- isopropylmalate, via the formation of 2-isopropylmaleate. | 0.816 |
Sde_1308 | leuD | Sde_1308 | Sde_2085 | Pyruvate kinase; Belongs to the pyruvate kinase family. | 3-isopropylmalate dehydratase, small subunit; Catalyzes the isomerization between 2-isopropylmalate and 3- isopropylmalate, via the formation of 2-isopropylmaleate. Belongs to the LeuD family. LeuD type 1 subfamily. | 0.815 |
Sde_2543 | Sde_0661 | Sde_2543 | Sde_0661 | Acetolactate synthase, small subunit. | Malate dehydrogenase (oxaloacetate decarboxylating) (NADP+). | 0.827 |
Sde_2543 | Sde_1308 | Sde_2543 | Sde_1308 | Acetolactate synthase, small subunit. | Pyruvate kinase; Belongs to the pyruvate kinase family. | 0.800 |
Sde_2543 | Sde_2866 | Sde_2543 | Sde_2866 | Acetolactate synthase, small subunit. | D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding. | 0.811 |
Sde_2543 | ilvC | Sde_2543 | Sde_2539 | Acetolactate synthase, small subunit. | Ketol-acid reductoisomerase; Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol-acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3-dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3-hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate. | 0.998 |
Sde_2543 | ilvD | Sde_2543 | Sde_0358 | Acetolactate synthase, small subunit. | Dihydroxyacid dehydratase / methyl-accepting chemotaxis sensory transducer; Belongs to the IlvD/Edd family. | 0.806 |
Sde_2543 | leuA | Sde_2543 | Sde_2298 | Acetolactate synthase, small subunit. | 2-isopropylmalate synthase; Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3- hydroxy-4-methylpentanoate (2-isopropylmalate); Belongs to the alpha-IPM synthase/homocitrate synthase family. LeuA type 2 subfamily. | 0.951 |