node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
Sde_3337 | Sde_3339 | Sde_3337 | Sde_3339 | Penicillin-binding protein 6. Serine peptidase. MEROPS family S11; Belongs to the peptidase S11 family. | Putative lytic murein transglycosylase. | 0.676 |
Sde_3337 | mrdA | Sde_3337 | Sde_3341 | Penicillin-binding protein 6. Serine peptidase. MEROPS family S11; Belongs to the peptidase S11 family. | PAS/PAC sensor signal transduction histidine kinase / peptidoglycan glycosyltransferase; Catalyzes cross-linking of the peptidoglycan cell wall. Belongs to the transpeptidase family. MrdA subfamily. | 0.921 |
Sde_3337 | mrdB | Sde_3337 | Sde_3340 | Penicillin-binding protein 6. Serine peptidase. MEROPS family S11; Belongs to the peptidase S11 family. | Rod shape-determining protein RodA; Peptidoglycan polymerase that is essential for cell wall elongation; Belongs to the SEDS family. MrdB/RodA subfamily. | 0.602 |
Sde_3337 | rlmH | Sde_3337 | Sde_3342 | Penicillin-binding protein 6. Serine peptidase. MEROPS family S11; Belongs to the peptidase S11 family. | Protein of unknown function DUF163; Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA; Belongs to the RNA methyltransferase RlmH family. | 0.636 |
Sde_3337 | rlpA | Sde_3337 | Sde_3338 | Penicillin-binding protein 6. Serine peptidase. MEROPS family S11; Belongs to the peptidase S11 family. | Rare lipoprotein A; Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides. | 0.654 |
Sde_3337 | rsfS | Sde_3337 | Sde_3343 | Penicillin-binding protein 6. Serine peptidase. MEROPS family S11; Belongs to the peptidase S11 family. | Iojap-related protein; Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation. | 0.409 |
Sde_3339 | Sde_3337 | Sde_3339 | Sde_3337 | Putative lytic murein transglycosylase. | Penicillin-binding protein 6. Serine peptidase. MEROPS family S11; Belongs to the peptidase S11 family. | 0.676 |
Sde_3339 | mrdA | Sde_3339 | Sde_3341 | Putative lytic murein transglycosylase. | PAS/PAC sensor signal transduction histidine kinase / peptidoglycan glycosyltransferase; Catalyzes cross-linking of the peptidoglycan cell wall. Belongs to the transpeptidase family. MrdA subfamily. | 0.832 |
Sde_3339 | mrdB | Sde_3339 | Sde_3340 | Putative lytic murein transglycosylase. | Rod shape-determining protein RodA; Peptidoglycan polymerase that is essential for cell wall elongation; Belongs to the SEDS family. MrdB/RodA subfamily. | 0.744 |
Sde_3339 | nadD | Sde_3339 | Sde_3344 | Putative lytic murein transglycosylase. | Nicotinate-nucleotide adenylyltransferase; Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD). | 0.518 |
Sde_3339 | proA | Sde_3339 | Sde_3345 | Putative lytic murein transglycosylase. | Glutamate-5-semialdehyde dehydrogenase; Catalyzes the NADPH-dependent reduction of L-glutamate 5- phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5-carboxylate. Belongs to the gamma-glutamyl phosphate reductase family. | 0.489 |
Sde_3339 | rlmH | Sde_3339 | Sde_3342 | Putative lytic murein transglycosylase. | Protein of unknown function DUF163; Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA; Belongs to the RNA methyltransferase RlmH family. | 0.670 |
Sde_3339 | rlpA | Sde_3339 | Sde_3338 | Putative lytic murein transglycosylase. | Rare lipoprotein A; Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides. | 0.808 |
Sde_3339 | rsfS | Sde_3339 | Sde_3343 | Putative lytic murein transglycosylase. | Iojap-related protein; Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation. | 0.609 |
mrdA | Sde_3337 | Sde_3341 | Sde_3337 | PAS/PAC sensor signal transduction histidine kinase / peptidoglycan glycosyltransferase; Catalyzes cross-linking of the peptidoglycan cell wall. Belongs to the transpeptidase family. MrdA subfamily. | Penicillin-binding protein 6. Serine peptidase. MEROPS family S11; Belongs to the peptidase S11 family. | 0.921 |
mrdA | Sde_3339 | Sde_3341 | Sde_3339 | PAS/PAC sensor signal transduction histidine kinase / peptidoglycan glycosyltransferase; Catalyzes cross-linking of the peptidoglycan cell wall. Belongs to the transpeptidase family. MrdA subfamily. | Putative lytic murein transglycosylase. | 0.832 |
mrdA | mrdB | Sde_3341 | Sde_3340 | PAS/PAC sensor signal transduction histidine kinase / peptidoglycan glycosyltransferase; Catalyzes cross-linking of the peptidoglycan cell wall. Belongs to the transpeptidase family. MrdA subfamily. | Rod shape-determining protein RodA; Peptidoglycan polymerase that is essential for cell wall elongation; Belongs to the SEDS family. MrdB/RodA subfamily. | 0.998 |
mrdA | nadD | Sde_3341 | Sde_3344 | PAS/PAC sensor signal transduction histidine kinase / peptidoglycan glycosyltransferase; Catalyzes cross-linking of the peptidoglycan cell wall. Belongs to the transpeptidase family. MrdA subfamily. | Nicotinate-nucleotide adenylyltransferase; Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD). | 0.643 |
mrdA | proA | Sde_3341 | Sde_3345 | PAS/PAC sensor signal transduction histidine kinase / peptidoglycan glycosyltransferase; Catalyzes cross-linking of the peptidoglycan cell wall. Belongs to the transpeptidase family. MrdA subfamily. | Glutamate-5-semialdehyde dehydrogenase; Catalyzes the NADPH-dependent reduction of L-glutamate 5- phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5-carboxylate. Belongs to the gamma-glutamyl phosphate reductase family. | 0.650 |
mrdA | rlmH | Sde_3341 | Sde_3342 | PAS/PAC sensor signal transduction histidine kinase / peptidoglycan glycosyltransferase; Catalyzes cross-linking of the peptidoglycan cell wall. Belongs to the transpeptidase family. MrdA subfamily. | Protein of unknown function DUF163; Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA; Belongs to the RNA methyltransferase RlmH family. | 0.937 |