node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
OEOE_0670 | ddl | OEOE_0670 | OEOE_0672 | Cell division membrane protein; Belongs to the SEDS family. | D-alanine--D-alanine ligase; Cell wall formation. | 0.816 |
OEOE_0670 | murA | OEOE_0670 | OEOE_1785 | Cell division membrane protein; Belongs to the SEDS family. | UDP-N-acetylglucosamine 1-carboxyvinyltransferase; Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine; Belongs to the EPSP synthase family. MurA subfamily. | 0.792 |
OEOE_0670 | murB | OEOE_0670 | OEOE_1658 | Cell division membrane protein; Belongs to the SEDS family. | UDP-N-acetylmuramate dehydrogenase; Cell wall formation. | 0.505 |
OEOE_0670 | murC | OEOE_0670 | OEOE_1269 | Cell division membrane protein; Belongs to the SEDS family. | UDP-N-acetylmuramate--L-alanine ligase; Cell wall formation; Belongs to the MurCDEF family. | 0.884 |
OEOE_0670 | murD | OEOE_0670 | OEOE_1147 | Cell division membrane protein; Belongs to the SEDS family. | UDP-N-acetylmuramoylalanine--D-glutamate ligase; Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA). Belongs to the MurCDEF family. | 0.855 |
OEOE_0670 | murF | OEOE_0670 | OEOE_1644 | Cell division membrane protein; Belongs to the SEDS family. | UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D- alanine ligase; Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein; Belongs to the MurCDEF family. MurF subfamily. | 0.852 |
OEOE_0670 | murG | OEOE_0670 | OEOE_1146 | Cell division membrane protein; Belongs to the SEDS family. | Undecaprenyl-PP-MurNAc-pentapeptide-UDPGlcNAc GlcNAc transferase; Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II); Belongs to the glycosyltransferase 28 family. MurG subfamily. | 0.915 |
OEOE_0670 | polA | OEOE_0670 | OEOE_0673 | Cell division membrane protein; Belongs to the SEDS family. | DNA polymerase I; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity. | 0.741 |
OEOE_1641 | ddl | OEOE_1641 | OEOE_0672 | Alanine racemase; Catalyzes the interconversion of L-alanine and D-alanine. May also act on other amino acids; Belongs to the alanine racemase family. | D-alanine--D-alanine ligase; Cell wall formation. | 0.950 |
OEOE_1641 | dltC | OEOE_1641 | OEOE_0287 | Alanine racemase; Catalyzes the interconversion of L-alanine and D-alanine. May also act on other amino acids; Belongs to the alanine racemase family. | D-alanyl transfer protein; Carrier protein involved in the D-alanylation of lipoteichoic acid (LTA). The loading of thioester-linked D-alanine onto DltC is catalyzed by D-alanine--D-alanyl carrier protein ligase DltA. The DltC- carried D-alanyl group is further transferred to cell membrane phosphatidylglycerol (PG) by forming an ester bond, probably catalyzed by DltD. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall. | 0.903 |
OEOE_1641 | murA | OEOE_1641 | OEOE_1785 | Alanine racemase; Catalyzes the interconversion of L-alanine and D-alanine. May also act on other amino acids; Belongs to the alanine racemase family. | UDP-N-acetylglucosamine 1-carboxyvinyltransferase; Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine; Belongs to the EPSP synthase family. MurA subfamily. | 0.423 |
OEOE_1641 | murC | OEOE_1641 | OEOE_1269 | Alanine racemase; Catalyzes the interconversion of L-alanine and D-alanine. May also act on other amino acids; Belongs to the alanine racemase family. | UDP-N-acetylmuramate--L-alanine ligase; Cell wall formation; Belongs to the MurCDEF family. | 0.589 |
OEOE_1641 | murD | OEOE_1641 | OEOE_1147 | Alanine racemase; Catalyzes the interconversion of L-alanine and D-alanine. May also act on other amino acids; Belongs to the alanine racemase family. | UDP-N-acetylmuramoylalanine--D-glutamate ligase; Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA). Belongs to the MurCDEF family. | 0.645 |
OEOE_1641 | murF | OEOE_1641 | OEOE_1644 | Alanine racemase; Catalyzes the interconversion of L-alanine and D-alanine. May also act on other amino acids; Belongs to the alanine racemase family. | UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D- alanine ligase; Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein; Belongs to the MurCDEF family. MurF subfamily. | 0.967 |
ddl | OEOE_0670 | OEOE_0672 | OEOE_0670 | D-alanine--D-alanine ligase; Cell wall formation. | Cell division membrane protein; Belongs to the SEDS family. | 0.816 |
ddl | OEOE_1641 | OEOE_0672 | OEOE_1641 | D-alanine--D-alanine ligase; Cell wall formation. | Alanine racemase; Catalyzes the interconversion of L-alanine and D-alanine. May also act on other amino acids; Belongs to the alanine racemase family. | 0.950 |
ddl | dltC | OEOE_0672 | OEOE_0287 | D-alanine--D-alanine ligase; Cell wall formation. | D-alanyl transfer protein; Carrier protein involved in the D-alanylation of lipoteichoic acid (LTA). The loading of thioester-linked D-alanine onto DltC is catalyzed by D-alanine--D-alanyl carrier protein ligase DltA. The DltC- carried D-alanyl group is further transferred to cell membrane phosphatidylglycerol (PG) by forming an ester bond, probably catalyzed by DltD. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall. | 0.904 |
ddl | murA | OEOE_0672 | OEOE_1785 | D-alanine--D-alanine ligase; Cell wall formation. | UDP-N-acetylglucosamine 1-carboxyvinyltransferase; Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine; Belongs to the EPSP synthase family. MurA subfamily. | 0.781 |
ddl | murB | OEOE_0672 | OEOE_1658 | D-alanine--D-alanine ligase; Cell wall formation. | UDP-N-acetylmuramate dehydrogenase; Cell wall formation. | 0.968 |
ddl | murC | OEOE_0672 | OEOE_1269 | D-alanine--D-alanine ligase; Cell wall formation. | UDP-N-acetylmuramate--L-alanine ligase; Cell wall formation; Belongs to the MurCDEF family. | 0.988 |