STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
gmkGuanylate kinase; Essential for recycling GMP and indirectly, cGMP. (186 aa)    
Predicted Functional Partners:
guaA
GMP synthase (glutamine-hydrolyzing); Catalyzes the synthesis of GMP from XMP.
 
 
 0.964
apt
Adenine phosphoribosyltransferase; Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis.
  
 
 0.962
rpoZ
DNA-directed RNA polymerase, omega subunit; Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits.
  
  
 0.957
Tery_2926
PFAM: pyruvate kinase PEP-utilising enzyme, mobile region; KEGG: ava:Ava_1694 pyruvate kinase; Belongs to the pyruvate kinase family.
  
 
 0.946
ndk
Nucleoside diphosphate kinase; Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate; Belongs to the NDK family.
   
 0.932
Tery_2653
(p)ppGpp synthetase I, SpoT/RelA; In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance.
 
 
 0.928
Tery_2045
Putative signal transduction protein with EFhand domain; PFAM: Calcium-binding EF-hand; KEGG: syf:Synpcc7942_0131 cyclic nucleotide-binding domain (cNMP-BD) protein.
    
 0.925
Tery_0425
TIGRFAM: Protein splicing (intein) site; SMART: Hedgehog/intein hint domain-like Hedgehog/intein hint-like; KEGG: ana:all4035 unknown protein.
     
  0.900
Tery_1774
5'-nucleotidase / 3'-nucleotidase / exopolyphosphatase; KEGG: ana:alr3139 putative acid phosphatase; TIGRFAM: stationary-phase survival protein SurE; PFAM: Survival protein SurE.
     
  0.900
Tery_2384
3'-nucleotidase / exopolyphosphatase / 5'-nucleotidase; KEGG: ana:alr3139 putative acid phosphatase; TIGRFAM: stationary-phase survival protein SurE; PFAM: Survival protein SurE.
     
  0.900
Your Current Organism:
Trichodesmium erythraeum
NCBI taxonomy Id: 203124
Other names: T. erythraeum IMS101, Trichodesmium erythraeum IMS101, Trichodesmium erythraeum str. IMS101, Trichodesmium erythraeum strain IMS101, Trichodesmium sp. IMS101
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