rpmA protein (Tropheryma whipplei) - STRING interaction network

Nodes:

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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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query proteins and first shell of interactors

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second shell of interactors

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proteins of unknown 3D structure

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a 3D structure is known or predicted

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Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

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experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

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textmining

co-expression

protein homology

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[Homology]

Score

rpmA

50S ribosomal protein L27; Belongs to the bacterial ribosomal protein bL27 family. (82 aa)

Predicted Functional Partners:

rplI

0.999

rpsR

0.999

rpsF

0.999

rplM

0.999

rpsI

0.999

rpmI

0.999

rplT

0.999

rpsT

0.999

rpsD

0.999

rpsO

0.999

Your Current Organism:

Tropheryma whipplei

NCBI taxonomy Id: 203267
Other names: T. whipplei str. Twist, Tropheryma whipplei Twist, Tropheryma whipplei str. Twist, Tropheryma whipplei strain Twist

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
rplI	rplM	TWT_105	TWT_144	50S ribosomal protein L9; Binds to the 23S rRNA.	50S ribosomal protein L13; This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly.	0.999
rplI	rplT	TWT_105	TWT_166	50S ribosomal protein L9; Binds to the 23S rRNA.	50S ribosomal protein L20; Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit.	0.999
rplI	rpmA	TWT_105	TWT_472	50S ribosomal protein L9; Binds to the 23S rRNA.	50S ribosomal protein L27; Belongs to the bacterial ribosomal protein bL27 family.	0.999
rplI	rpmI	TWT_105	TWT_165	50S ribosomal protein L9; Binds to the 23S rRNA.	50S ribosomal protein L35; Belongs to the bacterial ribosomal protein bL35 family.	0.999
rplI	rpsD	TWT_105	TWT_378	50S ribosomal protein L9; Binds to the 23S rRNA.	30S ribosomal protein S4; One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit.	0.999
rplI	rpsF	TWT_105	TWT_108	50S ribosomal protein L9; Binds to the 23S rRNA.	30S ribosomal protein S6; Binds together with S18 to 16S ribosomal RNA.	0.999
rplI	rpsI	TWT_105	TWT_145	50S ribosomal protein L9; Binds to the 23S rRNA.	30S ribosomal protein S9; Belongs to the universal ribosomal protein uS9 family.	0.999
rplI	rpsO	TWT_105	TWT_422	50S ribosomal protein L9; Binds to the 23S rRNA.	30S ribosomal protein S15; One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it helps nucleate assembly of the platform of the 30S subunit by binding and bridging several RNA helices of the 16S rRNA.	0.999
rplI	rpsR	TWT_105	TWT_106	50S ribosomal protein L9; Binds to the 23S rRNA.	30S ribosomal protein S18; Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit; Belongs to the bacterial ribosomal protein bS18 family.	0.999
rplI	rpsT	TWT_105	TWT_276	50S ribosomal protein L9; Binds to the 23S rRNA.	30S ribosomal protein S20; Binds directly to 16S ribosomal RNA.	0.999
rplM	rplI	TWT_144	TWT_105	50S ribosomal protein L13; This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly.	50S ribosomal protein L9; Binds to the 23S rRNA.	0.999
rplM	rplT	TWT_144	TWT_166	50S ribosomal protein L13; This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly.	50S ribosomal protein L20; Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit.	0.999
rplM	rpmA	TWT_144	TWT_472	50S ribosomal protein L13; This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly.	50S ribosomal protein L27; Belongs to the bacterial ribosomal protein bL27 family.	0.999
rplM	rpmI	TWT_144	TWT_165	50S ribosomal protein L13; This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly.	50S ribosomal protein L35; Belongs to the bacterial ribosomal protein bL35 family.	0.999
rplM	rpsD	TWT_144	TWT_378	50S ribosomal protein L13; This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly.	30S ribosomal protein S4; One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit.	0.999
rplM	rpsF	TWT_144	TWT_108	50S ribosomal protein L13; This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly.	30S ribosomal protein S6; Binds together with S18 to 16S ribosomal RNA.	0.999
rplM	rpsI	TWT_144	TWT_145	50S ribosomal protein L13; This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly.	30S ribosomal protein S9; Belongs to the universal ribosomal protein uS9 family.	0.999
rplM	rpsO	TWT_144	TWT_422	50S ribosomal protein L13; This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly.	30S ribosomal protein S15; One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it helps nucleate assembly of the platform of the 30S subunit by binding and bridging several RNA helices of the 16S rRNA.	0.999
rplM	rpsR	TWT_144	TWT_106	50S ribosomal protein L13; This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly.	30S ribosomal protein S18; Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit; Belongs to the bacterial ribosomal protein bS18 family.	0.999
rplM	rpsT	TWT_144	TWT_276	50S ribosomal protein L13; This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly.	30S ribosomal protein S20; Binds directly to 16S ribosomal RNA.	0.999