unknown-4 protein (Blochmannia floridanus) - STRING interaction network

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Score

unknown-4

Transcription regulator protein, MarR family; COG category=K. (144 aa)

Predicted Functional Partners:

aroC

0.881

fabB

0.828

dut

0.724

unknown

0.553

yccV

0.502

birA

0.492

gmk

0.445

Your Current Organism:

Blochmannia floridanus

NCBI taxonomy Id: 203907
Other names: C. Blochmannia floridanus, Candidatus Blochmannia floridanus

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
aroC	dut	Bfl500	Bfl613	Chorismate synthase; Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system.	Deoxyuridine 5'-triphosphate nucleotidohydrolase; This enzyme is involved in nucleotide metabolism: it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA; Belongs to the dUTPase family.	0.729
aroC	fabB	Bfl500	Bfl498	Chorismate synthase; Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system.	3-oxoacyl-[acyl-carrier-protein] synthase I; COG category=I; Belongs to the thiolase-like superfamily. Beta-ketoacyl-ACP synthases family.	0.826
aroC	unknown-4	Bfl500	Bfl615	Chorismate synthase; Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system.	Transcription regulator protein, MarR family; COG category=K.	0.881
birA	fabB	Bfl184	Bfl498	Bifunctional protein: biotin operon repressor and biotin-[acetyl-CoA carboxylase] synthetase; COG category=K.	3-oxoacyl-[acyl-carrier-protein] synthase I; COG category=I; Belongs to the thiolase-like superfamily. Beta-ketoacyl-ACP synthases family.	0.535
birA	unknown-4	Bfl184	Bfl615	Bifunctional protein: biotin operon repressor and biotin-[acetyl-CoA carboxylase] synthetase; COG category=K.	Transcription regulator protein, MarR family; COG category=K.	0.492
dut	aroC	Bfl613	Bfl500	Deoxyuridine 5'-triphosphate nucleotidohydrolase; This enzyme is involved in nucleotide metabolism: it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA; Belongs to the dUTPase family.	Chorismate synthase; Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system.	0.729
dut	fabB	Bfl613	Bfl498	Deoxyuridine 5'-triphosphate nucleotidohydrolase; This enzyme is involved in nucleotide metabolism: it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA; Belongs to the dUTPase family.	3-oxoacyl-[acyl-carrier-protein] synthase I; COG category=I; Belongs to the thiolase-like superfamily. Beta-ketoacyl-ACP synthases family.	0.642
dut	unknown-4	Bfl613	Bfl615	Deoxyuridine 5'-triphosphate nucleotidohydrolase; This enzyme is involved in nucleotide metabolism: it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA; Belongs to the dUTPase family.	Transcription regulator protein, MarR family; COG category=K.	0.724
fabB	aroC	Bfl498	Bfl500	3-oxoacyl-[acyl-carrier-protein] synthase I; COG category=I; Belongs to the thiolase-like superfamily. Beta-ketoacyl-ACP synthases family.	Chorismate synthase; Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system.	0.826
fabB	birA	Bfl498	Bfl184	3-oxoacyl-[acyl-carrier-protein] synthase I; COG category=I; Belongs to the thiolase-like superfamily. Beta-ketoacyl-ACP synthases family.	Bifunctional protein: biotin operon repressor and biotin-[acetyl-CoA carboxylase] synthetase; COG category=K.	0.535
fabB	dut	Bfl498	Bfl613	3-oxoacyl-[acyl-carrier-protein] synthase I; COG category=I; Belongs to the thiolase-like superfamily. Beta-ketoacyl-ACP synthases family.	Deoxyuridine 5'-triphosphate nucleotidohydrolase; This enzyme is involved in nucleotide metabolism: it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA; Belongs to the dUTPase family.	0.642
fabB	unknown-4	Bfl498	Bfl615	3-oxoacyl-[acyl-carrier-protein] synthase I; COG category=I; Belongs to the thiolase-like superfamily. Beta-ketoacyl-ACP synthases family.	Transcription regulator protein, MarR family; COG category=K.	0.828
gmk	unknown-4	Bfl616	Bfl615	Guanylate kinase; Essential for recycling GMP and indirectly, cGMP.	Transcription regulator protein, MarR family; COG category=K.	0.445
unknown	unknown-4	Bfl019	Bfl615	Probable transmembrane protein; COG category=P.	Transcription regulator protein, MarR family; COG category=K.	0.553
unknown-4	aroC	Bfl615	Bfl500	Transcription regulator protein, MarR family; COG category=K.	Chorismate synthase; Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system.	0.881
unknown-4	birA	Bfl615	Bfl184	Transcription regulator protein, MarR family; COG category=K.	Bifunctional protein: biotin operon repressor and biotin-[acetyl-CoA carboxylase] synthetase; COG category=K.	0.492
unknown-4	dut	Bfl615	Bfl613	Transcription regulator protein, MarR family; COG category=K.	Deoxyuridine 5'-triphosphate nucleotidohydrolase; This enzyme is involved in nucleotide metabolism: it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA; Belongs to the dUTPase family.	0.724
unknown-4	fabB	Bfl615	Bfl498	Transcription regulator protein, MarR family; COG category=K.	3-oxoacyl-[acyl-carrier-protein] synthase I; COG category=I; Belongs to the thiolase-like superfamily. Beta-ketoacyl-ACP synthases family.	0.828
unknown-4	gmk	Bfl615	Bfl616	Transcription regulator protein, MarR family; COG category=K.	Guanylate kinase; Essential for recycling GMP and indirectly, cGMP.	0.445
unknown-4	unknown	Bfl615	Bfl019	Transcription regulator protein, MarR family; COG category=K.	Probable transmembrane protein; COG category=P.	0.553