node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
apt | gmk | Bfl300 | Bfl616 | Adenine phosphoribosyltransferase; Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis. | Guanylate kinase; Essential for recycling GMP and indirectly, cGMP. | 0.960 |
apt | guaA | Bfl300 | Bfl527 | Adenine phosphoribosyltransferase; Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis. | GMP synthase (glutamine-hydrolyzing); Catalyzes the synthesis of GMP from XMP. | 0.994 |
apt | polA | Bfl300 | Bfl619 | Adenine phosphoribosyltransferase; Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis. | DNA polymerase I; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity; Belongs to the DNA polymerase type-A family. | 0.500 |
argS | gmk | Bfl453 | Bfl616 | arginyl-tRNA synthetase; COG category=J. | Guanylate kinase; Essential for recycling GMP and indirectly, cGMP. | 0.737 |
argS | guaA | Bfl453 | Bfl527 | arginyl-tRNA synthetase; COG category=J. | GMP synthase (glutamine-hydrolyzing); Catalyzes the synthesis of GMP from XMP. | 0.988 |
argS | polA | Bfl453 | Bfl619 | arginyl-tRNA synthetase; COG category=J. | DNA polymerase I; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity; Belongs to the DNA polymerase type-A family. | 0.569 |
gmk | apt | Bfl616 | Bfl300 | Guanylate kinase; Essential for recycling GMP and indirectly, cGMP. | Adenine phosphoribosyltransferase; Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis. | 0.960 |
gmk | argS | Bfl616 | Bfl453 | Guanylate kinase; Essential for recycling GMP and indirectly, cGMP. | arginyl-tRNA synthetase; COG category=J. | 0.737 |
gmk | guaA | Bfl616 | Bfl527 | Guanylate kinase; Essential for recycling GMP and indirectly, cGMP. | GMP synthase (glutamine-hydrolyzing); Catalyzes the synthesis of GMP from XMP. | 0.960 |
gmk | ndk | Bfl616 | Bfl533 | Guanylate kinase; Essential for recycling GMP and indirectly, cGMP. | Pseudogene of GcpE protein (protein E); Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate; Belongs to the NDK family. | 0.930 |
gmk | nrdA | Bfl616 | Bfl478 | Guanylate kinase; Essential for recycling GMP and indirectly, cGMP. | Ribonucleoside-diphosphate reductase 1 alpha chain; Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides. | 0.907 |
gmk | nrdB | Bfl616 | Bfl479 | Guanylate kinase; Essential for recycling GMP and indirectly, cGMP. | Ribonucleoside-diphosphate reductase 1 beta chain; COG category=F. | 0.901 |
gmk | polA | Bfl616 | Bfl619 | Guanylate kinase; Essential for recycling GMP and indirectly, cGMP. | DNA polymerase I; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity; Belongs to the DNA polymerase type-A family. | 0.892 |
gmk | pykA | Bfl616 | Bfl450 | Guanylate kinase; Essential for recycling GMP and indirectly, cGMP. | Pyruvate kinase A; COG category=G; Belongs to the pyruvate kinase family. | 0.912 |
gmk | rpoZ | Bfl616 | Bfl617 | Guanylate kinase; Essential for recycling GMP and indirectly, cGMP. | DNA-directed RNA polymerase omega chain; Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits. | 0.967 |
gmk | yicC | Bfl616 | Bfl614 | Guanylate kinase; Essential for recycling GMP and indirectly, cGMP. | Uncharacterized stress-induced protein; COG category=S. | 0.804 |
guaA | apt | Bfl527 | Bfl300 | GMP synthase (glutamine-hydrolyzing); Catalyzes the synthesis of GMP from XMP. | Adenine phosphoribosyltransferase; Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis. | 0.994 |
guaA | argS | Bfl527 | Bfl453 | GMP synthase (glutamine-hydrolyzing); Catalyzes the synthesis of GMP from XMP. | arginyl-tRNA synthetase; COG category=J. | 0.988 |
guaA | gmk | Bfl527 | Bfl616 | GMP synthase (glutamine-hydrolyzing); Catalyzes the synthesis of GMP from XMP. | Guanylate kinase; Essential for recycling GMP and indirectly, cGMP. | 0.960 |
guaA | ndk | Bfl527 | Bfl533 | GMP synthase (glutamine-hydrolyzing); Catalyzes the synthesis of GMP from XMP. | Pseudogene of GcpE protein (protein E); Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate; Belongs to the NDK family. | 0.576 |