node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
ABF39689.1 | ABF39690.1 | Acid345_0684 | Acid345_0685 | Endoribonuclease L-PSP. | Betaine-aldehyde dehydrogenase; Belongs to the aldehyde dehydrogenase family. | 0.982 |
ABF39689.1 | kmo | Acid345_0684 | Acid345_0681 | Endoribonuclease L-PSP. | Monooxygenase, FAD-binding protein; Catalyzes the hydroxylation of L-kynurenine (L-Kyn) to form 3-hydroxy-L-kynurenine (L-3OHKyn). Required for synthesis of quinolinic acid; Belongs to the aromatic-ring hydroxylase family. KMO subfamily. | 0.877 |
ABF39689.1 | kynA | Acid345_0684 | Acid345_0682 | Endoribonuclease L-PSP. | Tryptophan 2,3-dioxygenase apoenzyme; Heme-dependent dioxygenase that catalyzes the oxidative cleavage of the L-tryptophan (L-Trp) pyrrole ring and converts L- tryptophan to N-formyl-L-kynurenine. Catalyzes the oxidative cleavage of the indole moiety. | 0.886 |
ABF39689.1 | kynU | Acid345_0684 | Acid345_0680 | Endoribonuclease L-PSP. | Kynureninase; Catalyzes the cleavage of L-kynurenine (L-Kyn) and L-3- hydroxykynurenine (L-3OHKyn) into anthranilic acid (AA) and 3- hydroxyanthranilic acid (3-OHAA), respectively. | 0.858 |
ABF39689.1 | nbaC | Acid345_0684 | Acid345_0683 | Endoribonuclease L-PSP. | 3-hydroxyanthranilate 3,4-dioxygenase; Catalyzes the oxidative ring opening of 3-hydroxyanthranilate to 2-amino-3-carboxymuconate semialdehyde, which spontaneously cyclizes to quinolinate; Belongs to the 3-HAO family. | 0.914 |
ABF39690.1 | ABF39689.1 | Acid345_0685 | Acid345_0684 | Betaine-aldehyde dehydrogenase; Belongs to the aldehyde dehydrogenase family. | Endoribonuclease L-PSP. | 0.982 |
ABF39690.1 | kmo | Acid345_0685 | Acid345_0681 | Betaine-aldehyde dehydrogenase; Belongs to the aldehyde dehydrogenase family. | Monooxygenase, FAD-binding protein; Catalyzes the hydroxylation of L-kynurenine (L-Kyn) to form 3-hydroxy-L-kynurenine (L-3OHKyn). Required for synthesis of quinolinic acid; Belongs to the aromatic-ring hydroxylase family. KMO subfamily. | 0.831 |
ABF39690.1 | kynA | Acid345_0685 | Acid345_0682 | Betaine-aldehyde dehydrogenase; Belongs to the aldehyde dehydrogenase family. | Tryptophan 2,3-dioxygenase apoenzyme; Heme-dependent dioxygenase that catalyzes the oxidative cleavage of the L-tryptophan (L-Trp) pyrrole ring and converts L- tryptophan to N-formyl-L-kynurenine. Catalyzes the oxidative cleavage of the indole moiety. | 0.983 |
ABF39690.1 | kynU | Acid345_0685 | Acid345_0680 | Betaine-aldehyde dehydrogenase; Belongs to the aldehyde dehydrogenase family. | Kynureninase; Catalyzes the cleavage of L-kynurenine (L-Kyn) and L-3- hydroxykynurenine (L-3OHKyn) into anthranilic acid (AA) and 3- hydroxyanthranilic acid (3-OHAA), respectively. | 0.839 |
ABF39690.1 | nbaC | Acid345_0685 | Acid345_0683 | Betaine-aldehyde dehydrogenase; Belongs to the aldehyde dehydrogenase family. | 3-hydroxyanthranilate 3,4-dioxygenase; Catalyzes the oxidative ring opening of 3-hydroxyanthranilate to 2-amino-3-carboxymuconate semialdehyde, which spontaneously cyclizes to quinolinate; Belongs to the 3-HAO family. | 0.829 |
ABF40513.1 | kynA | Acid345_1511 | Acid345_0682 | Putative cyclase. | Tryptophan 2,3-dioxygenase apoenzyme; Heme-dependent dioxygenase that catalyzes the oxidative cleavage of the L-tryptophan (L-Trp) pyrrole ring and converts L- tryptophan to N-formyl-L-kynurenine. Catalyzes the oxidative cleavage of the indole moiety. | 0.670 |
ABF40513.1 | kynU | Acid345_1511 | Acid345_0680 | Putative cyclase. | Kynureninase; Catalyzes the cleavage of L-kynurenine (L-Kyn) and L-3- hydroxykynurenine (L-3OHKyn) into anthranilic acid (AA) and 3- hydroxyanthranilic acid (3-OHAA), respectively. | 0.863 |
ABF41611.1 | kynA | Acid345_2610 | Acid345_0682 | Kynurenine formamidase. | Tryptophan 2,3-dioxygenase apoenzyme; Heme-dependent dioxygenase that catalyzes the oxidative cleavage of the L-tryptophan (L-Trp) pyrrole ring and converts L- tryptophan to N-formyl-L-kynurenine. Catalyzes the oxidative cleavage of the indole moiety. | 0.670 |
ABF41611.1 | kynU | Acid345_2610 | Acid345_0680 | Kynurenine formamidase. | Kynureninase; Catalyzes the cleavage of L-kynurenine (L-Kyn) and L-3- hydroxykynurenine (L-3OHKyn) into anthranilic acid (AA) and 3- hydroxyanthranilic acid (3-OHAA), respectively. | 0.863 |
ABF41794.1 | kmo | Acid345_2793 | Acid345_0681 | Aminotransferase. | Monooxygenase, FAD-binding protein; Catalyzes the hydroxylation of L-kynurenine (L-Kyn) to form 3-hydroxy-L-kynurenine (L-3OHKyn). Required for synthesis of quinolinic acid; Belongs to the aromatic-ring hydroxylase family. KMO subfamily. | 0.528 |
ABF41794.1 | kynA | Acid345_2793 | Acid345_0682 | Aminotransferase. | Tryptophan 2,3-dioxygenase apoenzyme; Heme-dependent dioxygenase that catalyzes the oxidative cleavage of the L-tryptophan (L-Trp) pyrrole ring and converts L- tryptophan to N-formyl-L-kynurenine. Catalyzes the oxidative cleavage of the indole moiety. | 0.580 |
ABF41794.1 | kynU | Acid345_2793 | Acid345_0680 | Aminotransferase. | Kynureninase; Catalyzes the cleavage of L-kynurenine (L-Kyn) and L-3- hydroxykynurenine (L-3OHKyn) into anthranilic acid (AA) and 3- hydroxyanthranilic acid (3-OHAA), respectively. | 0.561 |
hmgA | kmo | Acid345_2005 | Acid345_0681 | Homogentisate 1,2-dioxygenase; Involved in the catabolism of homogentisate (2,5- dihydroxyphenylacetate or 2,5-OH-PhAc), a central intermediate in the degradation of phenylalanine and tyrosine. Catalyzes the oxidative ring cleavage of the aromatic ring of homogentisate to yield maleylacetoacetate. | Monooxygenase, FAD-binding protein; Catalyzes the hydroxylation of L-kynurenine (L-Kyn) to form 3-hydroxy-L-kynurenine (L-3OHKyn). Required for synthesis of quinolinic acid; Belongs to the aromatic-ring hydroxylase family. KMO subfamily. | 0.494 |
hmgA | kynA | Acid345_2005 | Acid345_0682 | Homogentisate 1,2-dioxygenase; Involved in the catabolism of homogentisate (2,5- dihydroxyphenylacetate or 2,5-OH-PhAc), a central intermediate in the degradation of phenylalanine and tyrosine. Catalyzes the oxidative ring cleavage of the aromatic ring of homogentisate to yield maleylacetoacetate. | Tryptophan 2,3-dioxygenase apoenzyme; Heme-dependent dioxygenase that catalyzes the oxidative cleavage of the L-tryptophan (L-Trp) pyrrole ring and converts L- tryptophan to N-formyl-L-kynurenine. Catalyzes the oxidative cleavage of the indole moiety. | 0.716 |
hmgA | kynU | Acid345_2005 | Acid345_0680 | Homogentisate 1,2-dioxygenase; Involved in the catabolism of homogentisate (2,5- dihydroxyphenylacetate or 2,5-OH-PhAc), a central intermediate in the degradation of phenylalanine and tyrosine. Catalyzes the oxidative ring cleavage of the aromatic ring of homogentisate to yield maleylacetoacetate. | Kynureninase; Catalyzes the cleavage of L-kynurenine (L-Kyn) and L-3- hydroxykynurenine (L-3OHKyn) into anthranilic acid (AA) and 3- hydroxyanthranilic acid (3-OHAA), respectively. | 0.574 |