STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
hemA1glutamyl-tRNA reductase; Catalyzes the NADPH-dependent reduction of glutamyl-tRNA(Glu) to glutamate 1-semialdehyde (GSA). (431 aa)    
Predicted Functional Partners:
ABF40539.1
Glutamate-1-semialdehyde 2,1-aminomutase; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.
 
 0.984
hemL
Glutamate-1-semialdehyde 2,1-aminomutase.
 
 0.984
hemC
Hydroxymethylbilane synthase; Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps. Belongs to the HMBS family.
  
 0.953
hemA2
glutamyl-tRNA reductase; Catalyzes the NADPH-dependent reduction of glutamyl-tRNA(Glu) to glutamate 1-semialdehyde (GSA).
  
  
 
0.912
gltX2
glutamyl-tRNA synthetase; Catalyzes the attachment of glutamate to tRNA(Glu) in a two- step reaction: glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu); Belongs to the class-I aminoacyl-tRNA synthetase family. Glutamate--tRNA ligase type 1 subfamily.
     
 0.909
ABF42028.1
Glutamate--tRNA ligase; Belongs to the class-I aminoacyl-tRNA synthetase family.
     
 0.909
ABF41563.1
uroporphyrinogen-III synthase; Catalyzes cyclization of the linear tetrapyrrole, hydroxymethylbilane, to the macrocyclic uroporphyrinogen III.
 
  
 0.845
ABF43300.1
Porphobilinogen synthase; Belongs to the ALAD family.
 
  
 0.842
ABF41376.1
uroporphyrinogen-III C-methyltransferase; Belongs to the precorrin methyltransferase family.
 
  
 0.756
ABF39762.1
Tetratricopeptide repeat protein.
       0.588
Your Current Organism:
Koribacter versatilis
NCBI taxonomy Id: 204669
Other names: Acidobacteria bacterium Ellin345, C. Koribacter versatilis Ellin345, Candidatus Koribacter versatilis Ellin345, Koribacter versatilis Ellin345, bacterium Ellin345
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