node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
ABF39068.1 | ABF42059.1 | Acid345_0063 | Acid345_3058 | Phosphoribosyltransferase. | Hypoxanthine phosphoribosyltransferase; Belongs to the purine/pyrimidine phosphoribosyltransferase family. | 0.913 |
ABF39068.1 | apt | Acid345_0063 | Acid345_3608 | Phosphoribosyltransferase. | Adenine phosphoribosyltransferase; Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis. | 0.929 |
ABF39068.1 | gmk | Acid345_0063 | Acid345_3778 | Phosphoribosyltransferase. | Guanylate kinase; Essential for recycling GMP and indirectly, cGMP. | 0.917 |
ABF39068.1 | guaA | Acid345_0063 | Acid345_1793 | Phosphoribosyltransferase. | GMP synthase (glutamine-hydrolyzing); Catalyzes the synthesis of GMP from XMP. | 0.942 |
ABF39180.1 | ABF40127.1 | Acid345_0175 | Acid345_1124 | (p)ppGpp synthetase I (GTP pyrophosphokinase), SpoT/RelA; In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance. | Ribonucleoside-diphosphate reductase; Catalyzes the reduction of ribonucleotides to deoxyribonucleotides. May function to provide a pool of deoxyribonucleotide precursors for DNA repair during oxygen limitation and/or for immediate growth after restoration of oxygen. | 0.901 |
ABF39180.1 | ABF43085.1 | Acid345_0175 | Acid345_4085 | (p)ppGpp synthetase I (GTP pyrophosphokinase), SpoT/RelA; In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance. | Pyruvate kinase; Belongs to the pyruvate kinase family. | 0.904 |
ABF39180.1 | ABF43669.1 | Acid345_0175 | Acid345_4669 | (p)ppGpp synthetase I (GTP pyrophosphokinase), SpoT/RelA; In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance. | Pyruvate kinase; Belongs to the pyruvate kinase family. | 0.917 |
ABF39180.1 | gmk | Acid345_0175 | Acid345_3778 | (p)ppGpp synthetase I (GTP pyrophosphokinase), SpoT/RelA; In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance. | Guanylate kinase; Essential for recycling GMP and indirectly, cGMP. | 0.922 |
ABF39180.1 | guaA | Acid345_0175 | Acid345_1793 | (p)ppGpp synthetase I (GTP pyrophosphokinase), SpoT/RelA; In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance. | GMP synthase (glutamine-hydrolyzing); Catalyzes the synthesis of GMP from XMP. | 0.430 |
ABF39180.1 | ndk | Acid345_0175 | Acid345_3873 | (p)ppGpp synthetase I (GTP pyrophosphokinase), SpoT/RelA; In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance. | Nucleoside diphosphate kinase; Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate; Belongs to the NDK family. | 0.916 |
ABF40127.1 | ABF39180.1 | Acid345_1124 | Acid345_0175 | Ribonucleoside-diphosphate reductase; Catalyzes the reduction of ribonucleotides to deoxyribonucleotides. May function to provide a pool of deoxyribonucleotide precursors for DNA repair during oxygen limitation and/or for immediate growth after restoration of oxygen. | (p)ppGpp synthetase I (GTP pyrophosphokinase), SpoT/RelA; In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance. | 0.901 |
ABF40127.1 | ABF43085.1 | Acid345_1124 | Acid345_4085 | Ribonucleoside-diphosphate reductase; Catalyzes the reduction of ribonucleotides to deoxyribonucleotides. May function to provide a pool of deoxyribonucleotide precursors for DNA repair during oxygen limitation and/or for immediate growth after restoration of oxygen. | Pyruvate kinase; Belongs to the pyruvate kinase family. | 0.908 |
ABF40127.1 | ABF43669.1 | Acid345_1124 | Acid345_4669 | Ribonucleoside-diphosphate reductase; Catalyzes the reduction of ribonucleotides to deoxyribonucleotides. May function to provide a pool of deoxyribonucleotide precursors for DNA repair during oxygen limitation and/or for immediate growth after restoration of oxygen. | Pyruvate kinase; Belongs to the pyruvate kinase family. | 0.908 |
ABF40127.1 | gmk | Acid345_1124 | Acid345_3778 | Ribonucleoside-diphosphate reductase; Catalyzes the reduction of ribonucleotides to deoxyribonucleotides. May function to provide a pool of deoxyribonucleotide precursors for DNA repair during oxygen limitation and/or for immediate growth after restoration of oxygen. | Guanylate kinase; Essential for recycling GMP and indirectly, cGMP. | 0.918 |
ABF40127.1 | guaA | Acid345_1124 | Acid345_1793 | Ribonucleoside-diphosphate reductase; Catalyzes the reduction of ribonucleotides to deoxyribonucleotides. May function to provide a pool of deoxyribonucleotide precursors for DNA repair during oxygen limitation and/or for immediate growth after restoration of oxygen. | GMP synthase (glutamine-hydrolyzing); Catalyzes the synthesis of GMP from XMP. | 0.553 |
ABF40127.1 | ndk | Acid345_1124 | Acid345_3873 | Ribonucleoside-diphosphate reductase; Catalyzes the reduction of ribonucleotides to deoxyribonucleotides. May function to provide a pool of deoxyribonucleotide precursors for DNA repair during oxygen limitation and/or for immediate growth after restoration of oxygen. | Nucleoside diphosphate kinase; Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate; Belongs to the NDK family. | 0.919 |
ABF42059.1 | ABF39068.1 | Acid345_3058 | Acid345_0063 | Hypoxanthine phosphoribosyltransferase; Belongs to the purine/pyrimidine phosphoribosyltransferase family. | Phosphoribosyltransferase. | 0.913 |
ABF42059.1 | apt | Acid345_3058 | Acid345_3608 | Hypoxanthine phosphoribosyltransferase; Belongs to the purine/pyrimidine phosphoribosyltransferase family. | Adenine phosphoribosyltransferase; Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis. | 0.929 |
ABF42059.1 | gmk | Acid345_3058 | Acid345_3778 | Hypoxanthine phosphoribosyltransferase; Belongs to the purine/pyrimidine phosphoribosyltransferase family. | Guanylate kinase; Essential for recycling GMP and indirectly, cGMP. | 0.917 |
ABF42059.1 | guaA | Acid345_3058 | Acid345_1793 | Hypoxanthine phosphoribosyltransferase; Belongs to the purine/pyrimidine phosphoribosyltransferase family. | GMP synthase (glutamine-hydrolyzing); Catalyzes the synthesis of GMP from XMP. | 0.942 |