node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
HEAR2174 | dapA | HEAR2174 | HEAR2175 | Putative lipoprotein; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative membrane component. | Dihydrodipicolinate synthase (DHDPS); Catalyzes the condensation of (S)-aspartate-beta-semialdehyde [(S)-ASA] and pyruvate to 4-hydroxy-tetrahydrodipicolinate (HTPA). | 0.664 |
asd | ask | HEAR1218 | HEAR1290 | Aspartate-semialdehyde dehydrogenase (ASA dehydrogenase) (ASADH); Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L-aspartyl- 4-phosphate; Belongs to the aspartate-semialdehyde dehydrogenase family. | Aspartokinase (Aspartate kinase); Function of homologous gene experimentally demonstrated in an other organism; enzyme; Belongs to the aspartokinase family. | 0.991 |
asd | dapA | HEAR1218 | HEAR2175 | Aspartate-semialdehyde dehydrogenase (ASA dehydrogenase) (ASADH); Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L-aspartyl- 4-phosphate; Belongs to the aspartate-semialdehyde dehydrogenase family. | Dihydrodipicolinate synthase (DHDPS); Catalyzes the condensation of (S)-aspartate-beta-semialdehyde [(S)-ASA] and pyruvate to 4-hydroxy-tetrahydrodipicolinate (HTPA). | 0.965 |
asd | dapB | HEAR1218 | HEAR2657 | Aspartate-semialdehyde dehydrogenase (ASA dehydrogenase) (ASADH); Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L-aspartyl- 4-phosphate; Belongs to the aspartate-semialdehyde dehydrogenase family. | Dihydrodipicolinate reductase (DHPR); Catalyzes the conversion of 4-hydroxy-tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate. | 0.765 |
asd | dapF | HEAR1218 | HEAR2955 | Aspartate-semialdehyde dehydrogenase (ASA dehydrogenase) (ASADH); Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L-aspartyl- 4-phosphate; Belongs to the aspartate-semialdehyde dehydrogenase family. | Diaminopimelate epimerase (DAP epimerase); Catalyzes the stereoinversion of LL-2,6-diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso-DAP), a precursor of L- lysine and an essential component of the bacterial peptidoglycan. | 0.825 |
asd | hom | HEAR1218 | HEAR2150 | Aspartate-semialdehyde dehydrogenase (ASA dehydrogenase) (ASADH); Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L-aspartyl- 4-phosphate; Belongs to the aspartate-semialdehyde dehydrogenase family. | Homoserine dehydrogenase; Function of homologous gene experimentally demonstrated in an other organism; enzyme. | 0.977 |
asd | lysA | HEAR1218 | HEAR3129 | Aspartate-semialdehyde dehydrogenase (ASA dehydrogenase) (ASADH); Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L-aspartyl- 4-phosphate; Belongs to the aspartate-semialdehyde dehydrogenase family. | Diaminopimelate decarboxylase (DAP decarboxylase); Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine. | 0.461 |
asd | pheA | HEAR1218 | HEAR2579 | Aspartate-semialdehyde dehydrogenase (ASA dehydrogenase) (ASADH); Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L-aspartyl- 4-phosphate; Belongs to the aspartate-semialdehyde dehydrogenase family. | Bifunctional P-protein [Includes: Chorismate mutase (CM); Function of homologous gene experimentally demonstrated in an other organism; enzyme. | 0.595 |
ask | asd | HEAR1290 | HEAR1218 | Aspartokinase (Aspartate kinase); Function of homologous gene experimentally demonstrated in an other organism; enzyme; Belongs to the aspartokinase family. | Aspartate-semialdehyde dehydrogenase (ASA dehydrogenase) (ASADH); Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L-aspartyl- 4-phosphate; Belongs to the aspartate-semialdehyde dehydrogenase family. | 0.991 |
ask | dapA | HEAR1290 | HEAR2175 | Aspartokinase (Aspartate kinase); Function of homologous gene experimentally demonstrated in an other organism; enzyme; Belongs to the aspartokinase family. | Dihydrodipicolinate synthase (DHDPS); Catalyzes the condensation of (S)-aspartate-beta-semialdehyde [(S)-ASA] and pyruvate to 4-hydroxy-tetrahydrodipicolinate (HTPA). | 0.733 |
ask | dapB | HEAR1290 | HEAR2657 | Aspartokinase (Aspartate kinase); Function of homologous gene experimentally demonstrated in an other organism; enzyme; Belongs to the aspartokinase family. | Dihydrodipicolinate reductase (DHPR); Catalyzes the conversion of 4-hydroxy-tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate. | 0.799 |
ask | dapF | HEAR1290 | HEAR2955 | Aspartokinase (Aspartate kinase); Function of homologous gene experimentally demonstrated in an other organism; enzyme; Belongs to the aspartokinase family. | Diaminopimelate epimerase (DAP epimerase); Catalyzes the stereoinversion of LL-2,6-diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso-DAP), a precursor of L- lysine and an essential component of the bacterial peptidoglycan. | 0.563 |
ask | hom | HEAR1290 | HEAR2150 | Aspartokinase (Aspartate kinase); Function of homologous gene experimentally demonstrated in an other organism; enzyme; Belongs to the aspartokinase family. | Homoserine dehydrogenase; Function of homologous gene experimentally demonstrated in an other organism; enzyme. | 0.892 |
ask | lysA | HEAR1290 | HEAR3129 | Aspartokinase (Aspartate kinase); Function of homologous gene experimentally demonstrated in an other organism; enzyme; Belongs to the aspartokinase family. | Diaminopimelate decarboxylase (DAP decarboxylase); Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine. | 0.698 |
ask | pheA | HEAR1290 | HEAR2579 | Aspartokinase (Aspartate kinase); Function of homologous gene experimentally demonstrated in an other organism; enzyme; Belongs to the aspartokinase family. | Bifunctional P-protein [Includes: Chorismate mutase (CM); Function of homologous gene experimentally demonstrated in an other organism; enzyme. | 0.643 |
dapA | HEAR2174 | HEAR2175 | HEAR2174 | Dihydrodipicolinate synthase (DHDPS); Catalyzes the condensation of (S)-aspartate-beta-semialdehyde [(S)-ASA] and pyruvate to 4-hydroxy-tetrahydrodipicolinate (HTPA). | Putative lipoprotein; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative membrane component. | 0.664 |
dapA | asd | HEAR2175 | HEAR1218 | Dihydrodipicolinate synthase (DHDPS); Catalyzes the condensation of (S)-aspartate-beta-semialdehyde [(S)-ASA] and pyruvate to 4-hydroxy-tetrahydrodipicolinate (HTPA). | Aspartate-semialdehyde dehydrogenase (ASA dehydrogenase) (ASADH); Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L-aspartyl- 4-phosphate; Belongs to the aspartate-semialdehyde dehydrogenase family. | 0.965 |
dapA | ask | HEAR2175 | HEAR1290 | Dihydrodipicolinate synthase (DHDPS); Catalyzes the condensation of (S)-aspartate-beta-semialdehyde [(S)-ASA] and pyruvate to 4-hydroxy-tetrahydrodipicolinate (HTPA). | Aspartokinase (Aspartate kinase); Function of homologous gene experimentally demonstrated in an other organism; enzyme; Belongs to the aspartokinase family. | 0.733 |
dapA | dapB | HEAR2175 | HEAR2657 | Dihydrodipicolinate synthase (DHDPS); Catalyzes the condensation of (S)-aspartate-beta-semialdehyde [(S)-ASA] and pyruvate to 4-hydroxy-tetrahydrodipicolinate (HTPA). | Dihydrodipicolinate reductase (DHPR); Catalyzes the conversion of 4-hydroxy-tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate. | 0.993 |
dapA | dapF | HEAR2175 | HEAR2955 | Dihydrodipicolinate synthase (DHDPS); Catalyzes the condensation of (S)-aspartate-beta-semialdehyde [(S)-ASA] and pyruvate to 4-hydroxy-tetrahydrodipicolinate (HTPA). | Diaminopimelate epimerase (DAP epimerase); Catalyzes the stereoinversion of LL-2,6-diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso-DAP), a precursor of L- lysine and an essential component of the bacterial peptidoglycan. | 0.813 |