STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
pepACytosol aminopeptidase (Leucine aminopeptidase) (LAP) (Leucyl aminopeptidase); Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N- terminal amino acids from various peptides. (503 aa)    
Predicted Functional Partners:
pepN
Aminopeptidase N (Alpha-aminoacylpeptide hydrolase); Function of homologous gene experimentally demonstrated in an other organism; enzyme.
   
 0.943
gshB1
Glutathione synthetase (Glutathione synthase) (GSH synthetase) (GSH-S) (GSHase); Function of homologous gene experimentally demonstrated in an other organism; enzyme; Belongs to the prokaryotic GSH synthase family.
   
 
 0.942
HEAR0614
Gamma-glutamyltranspeptidase; Function of strongly homologous gene; enzyme.
  
  
 0.921
HEAR2479
Putative gamma-glutamyltranspeptidase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme.
     
 0.908
gshA2
Gamma-glutamate-cysteine ligase (Gamma-glutamylcysteine synthetase) (Gamma-ECS) (GCS); Function of strongly homologous gene; enzyme; Belongs to the glutamate--cysteine ligase type 1 family. Type 1 subfamily.
     
 0.907
gshA1
Glutamate--cysteine ligase; Function of strongly homologous gene; enzyme.
    
 0.903
HEAR2518
Carboxylate-amine ligase; ATP-dependent carboxylate-amine ligase which exhibits weak glutamate--cysteine ligase activity; Belongs to the glutamate--cysteine ligase type 2 family. YbdK subfamily.
     
  0.900
glyA
Serine hydroxymethyltransferase (Serine methylase) (SHMT); Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism.
  
 
 0.836
HEAR1919
Cystathionine beta-lyase; Function of strongly homologous gene; enzyme.
     
  0.800
narG
Nitrate reductase, alpha subunit; Function of homologous gene experimentally demonstrated in an other organism; enzyme; Belongs to the prokaryotic molybdopterin-containing oxidoreductase family.
      
 0.740
Your Current Organism:
Herminiimonas arsenicoxydans
NCBI taxonomy Id: 204773
Other names: CCM 7303, DSM 17148, H. arsenicoxydans, Herminiimonas arsenicoxydans Muller et al. 2006, LMG 22961, LMG:22961, strain ULPAs1
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