node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
argS | cysS | HEAR0093 | HEAR1286 | Putative arginyl-tRNA synthetase (ArgS); Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme. | Cysteinyl-tRNA synthetase (Cysteine--tRNA ligase); Function of homologous gene experimentally demonstrated in an other organism; enzyme; Belongs to the class-I aminoacyl-tRNA synthetase family. | 0.621 |
argS | glnS | HEAR0093 | HEAR0612 | Putative arginyl-tRNA synthetase (ArgS); Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme. | Glutamine tRNA synthetase (Glutamine--tRNA ligase) (GlnRS); Function of homologous gene experimentally demonstrated in an other organism; enzyme. | 0.866 |
argS | gltX | HEAR0093 | HEAR0981 | Putative arginyl-tRNA synthetase (ArgS); Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme. | Glutamyl-tRNA synthetase (Glutamate--tRNA ligase) (GluRS); Catalyzes the attachment of glutamate to tRNA(Glu) in a two- step reaction: glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu); Belongs to the class-I aminoacyl-tRNA synthetase family. Glutamate--tRNA ligase type 1 subfamily. | 0.896 |
argS | ileS | HEAR0093 | HEAR0845 | Putative arginyl-tRNA synthetase (ArgS); Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme. | Isoleucine tRNA synthetase (Isoleucine--tRNA ligase) (IleRS); Catalyzes the attachment of isoleucine to tRNA(Ile). As IleRS can inadvertently accommodate and process structurally similar amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile). Belongs to the class-I aminoacyl-tRNA synthetase family. IleS type 1 subfamily. | 0.980 |
argS | leuS | HEAR0093 | HEAR2661 | Putative arginyl-tRNA synthetase (ArgS); Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme. | Leucyl-tRNA synthetase (Leucine--tRNA ligase) (LeuRS); Function of homologous gene experimentally demonstrated in an other organism; enzyme; Belongs to the class-I aminoacyl-tRNA synthetase family. | 0.957 |
argS | metG | HEAR0093 | HEAR0980 | Putative arginyl-tRNA synthetase (ArgS); Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme. | Methionine tRNA synthetase (Methionine--tRNA ligase) (MetRS); Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation. | 0.934 |
argS | pheT | HEAR0093 | HEAR1796 | Putative arginyl-tRNA synthetase (ArgS); Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme. | Phenylalanyl-tRNA synthetase beta chain (Phenylalanine--tRNA ligase beta chain) (PheRS); Function of homologous gene experimentally demonstrated in an other organism; enzyme; Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily. | 0.892 |
argS | proS | HEAR0093 | HEAR2781 | Putative arginyl-tRNA synthetase (ArgS); Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme. | Prolyl-tRNA synthetase (Proline--tRNA ligase) (ProRS) (Global RNA synthesis factor); Catalyzes the attachment of proline to tRNA(Pro) in a two- step reaction: proline is first activated by ATP to form Pro-AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other a [...] | 0.981 |
argS | valS | HEAR0093 | HEAR0261 | Putative arginyl-tRNA synthetase (ArgS); Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme. | Valyl-tRNA synthetase (Valine--tRNA ligase) (ValRS); Catalyzes the attachment of valine to tRNA(Val). As ValRS can inadvertently accommodate and process structurally similar amino acids such as threonine, to avoid such errors, it has a 'posttransfer' editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA- dependent manner; Belongs to the class-I aminoacyl-tRNA synthetase family. ValS type 1 subfamily. | 0.772 |
cysS | argS | HEAR1286 | HEAR0093 | Cysteinyl-tRNA synthetase (Cysteine--tRNA ligase); Function of homologous gene experimentally demonstrated in an other organism; enzyme; Belongs to the class-I aminoacyl-tRNA synthetase family. | Putative arginyl-tRNA synthetase (ArgS); Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme. | 0.621 |
cysS | glnS | HEAR1286 | HEAR0612 | Cysteinyl-tRNA synthetase (Cysteine--tRNA ligase); Function of homologous gene experimentally demonstrated in an other organism; enzyme; Belongs to the class-I aminoacyl-tRNA synthetase family. | Glutamine tRNA synthetase (Glutamine--tRNA ligase) (GlnRS); Function of homologous gene experimentally demonstrated in an other organism; enzyme. | 0.785 |
cysS | gltX | HEAR1286 | HEAR0981 | Cysteinyl-tRNA synthetase (Cysteine--tRNA ligase); Function of homologous gene experimentally demonstrated in an other organism; enzyme; Belongs to the class-I aminoacyl-tRNA synthetase family. | Glutamyl-tRNA synthetase (Glutamate--tRNA ligase) (GluRS); Catalyzes the attachment of glutamate to tRNA(Glu) in a two- step reaction: glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu); Belongs to the class-I aminoacyl-tRNA synthetase family. Glutamate--tRNA ligase type 1 subfamily. | 0.874 |
cysS | ileS | HEAR1286 | HEAR0845 | Cysteinyl-tRNA synthetase (Cysteine--tRNA ligase); Function of homologous gene experimentally demonstrated in an other organism; enzyme; Belongs to the class-I aminoacyl-tRNA synthetase family. | Isoleucine tRNA synthetase (Isoleucine--tRNA ligase) (IleRS); Catalyzes the attachment of isoleucine to tRNA(Ile). As IleRS can inadvertently accommodate and process structurally similar amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile). Belongs to the class-I aminoacyl-tRNA synthetase family. IleS type 1 subfamily. | 0.809 |
cysS | leuS | HEAR1286 | HEAR2661 | Cysteinyl-tRNA synthetase (Cysteine--tRNA ligase); Function of homologous gene experimentally demonstrated in an other organism; enzyme; Belongs to the class-I aminoacyl-tRNA synthetase family. | Leucyl-tRNA synthetase (Leucine--tRNA ligase) (LeuRS); Function of homologous gene experimentally demonstrated in an other organism; enzyme; Belongs to the class-I aminoacyl-tRNA synthetase family. | 0.912 |
cysS | metG | HEAR1286 | HEAR0980 | Cysteinyl-tRNA synthetase (Cysteine--tRNA ligase); Function of homologous gene experimentally demonstrated in an other organism; enzyme; Belongs to the class-I aminoacyl-tRNA synthetase family. | Methionine tRNA synthetase (Methionine--tRNA ligase) (MetRS); Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation. | 0.638 |
cysS | pheT | HEAR1286 | HEAR1796 | Cysteinyl-tRNA synthetase (Cysteine--tRNA ligase); Function of homologous gene experimentally demonstrated in an other organism; enzyme; Belongs to the class-I aminoacyl-tRNA synthetase family. | Phenylalanyl-tRNA synthetase beta chain (Phenylalanine--tRNA ligase beta chain) (PheRS); Function of homologous gene experimentally demonstrated in an other organism; enzyme; Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily. | 0.687 |
cysS | proS | HEAR1286 | HEAR2781 | Cysteinyl-tRNA synthetase (Cysteine--tRNA ligase); Function of homologous gene experimentally demonstrated in an other organism; enzyme; Belongs to the class-I aminoacyl-tRNA synthetase family. | Prolyl-tRNA synthetase (Proline--tRNA ligase) (ProRS) (Global RNA synthesis factor); Catalyzes the attachment of proline to tRNA(Pro) in a two- step reaction: proline is first activated by ATP to form Pro-AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other a [...] | 0.502 |
cysS | valS | HEAR1286 | HEAR0261 | Cysteinyl-tRNA synthetase (Cysteine--tRNA ligase); Function of homologous gene experimentally demonstrated in an other organism; enzyme; Belongs to the class-I aminoacyl-tRNA synthetase family. | Valyl-tRNA synthetase (Valine--tRNA ligase) (ValRS); Catalyzes the attachment of valine to tRNA(Val). As ValRS can inadvertently accommodate and process structurally similar amino acids such as threonine, to avoid such errors, it has a 'posttransfer' editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA- dependent manner; Belongs to the class-I aminoacyl-tRNA synthetase family. ValS type 1 subfamily. | 0.908 |
glnS | argS | HEAR0612 | HEAR0093 | Glutamine tRNA synthetase (Glutamine--tRNA ligase) (GlnRS); Function of homologous gene experimentally demonstrated in an other organism; enzyme. | Putative arginyl-tRNA synthetase (ArgS); Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme. | 0.866 |
glnS | cysS | HEAR0612 | HEAR1286 | Glutamine tRNA synthetase (Glutamine--tRNA ligase) (GlnRS); Function of homologous gene experimentally demonstrated in an other organism; enzyme. | Cysteinyl-tRNA synthetase (Cysteine--tRNA ligase); Function of homologous gene experimentally demonstrated in an other organism; enzyme; Belongs to the class-I aminoacyl-tRNA synthetase family. | 0.785 |