node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
HEAR0847 | cbpA1 | HEAR0847 | HEAR1440 | Conserved hypothetical protein; Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit. | Curved DNA-binding protein; Function of strongly homologous gene; factor. | 0.440 |
HEAR0847 | cbpA2 | HEAR0847 | HEAR1694 | Conserved hypothetical protein; Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit. | Curved DNA-binding protein; Function of strongly homologous gene; factor. | 0.440 |
HEAR0847 | dnaJ | HEAR0847 | HEAR2646 | Conserved hypothetical protein; Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit. | Chaperone protein DnaJ; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, D [...] | 0.479 |
HEAR0847 | prmA | HEAR0847 | HEAR2764 | Conserved hypothetical protein; Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit. | Ribosomal protein L11 methyltransferase (L11 Mtase); Methylates ribosomal protein L11; Belongs to the methyltransferase superfamily. PrmA family. | 0.801 |
HEAR2765 | accC | HEAR2765 | HEAR2763 | Conserved hypothetical protein; Homologs of previously reported genes of unknown function. | Biotin carboxylase (Acetyl-CoA carboxylase subunit A) (ACC); This protein is a component of the acetyl coenzyme A carboxylase complex; first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA. | 0.532 |
HEAR2765 | pkfB | HEAR2765 | HEAR2766 | Conserved hypothetical protein; Homologs of previously reported genes of unknown function. | Carbohydrate kinase; Function of strongly homologous gene; enzyme. | 0.555 |
HEAR2765 | prmA | HEAR2765 | HEAR2764 | Conserved hypothetical protein; Homologs of previously reported genes of unknown function. | Ribosomal protein L11 methyltransferase (L11 Mtase); Methylates ribosomal protein L11; Belongs to the methyltransferase superfamily. PrmA family. | 0.794 |
accC | HEAR2765 | HEAR2763 | HEAR2765 | Biotin carboxylase (Acetyl-CoA carboxylase subunit A) (ACC); This protein is a component of the acetyl coenzyme A carboxylase complex; first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA. | Conserved hypothetical protein; Homologs of previously reported genes of unknown function. | 0.532 |
accC | pkfB | HEAR2763 | HEAR2766 | Biotin carboxylase (Acetyl-CoA carboxylase subunit A) (ACC); This protein is a component of the acetyl coenzyme A carboxylase complex; first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA. | Carbohydrate kinase; Function of strongly homologous gene; enzyme. | 0.468 |
accC | prmA | HEAR2763 | HEAR2764 | Biotin carboxylase (Acetyl-CoA carboxylase subunit A) (ACC); This protein is a component of the acetyl coenzyme A carboxylase complex; first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA. | Ribosomal protein L11 methyltransferase (L11 Mtase); Methylates ribosomal protein L11; Belongs to the methyltransferase superfamily. PrmA family. | 0.537 |
cbpA1 | HEAR0847 | HEAR1440 | HEAR0847 | Curved DNA-binding protein; Function of strongly homologous gene; factor. | Conserved hypothetical protein; Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit. | 0.440 |
cbpA1 | prmA | HEAR1440 | HEAR2764 | Curved DNA-binding protein; Function of strongly homologous gene; factor. | Ribosomal protein L11 methyltransferase (L11 Mtase); Methylates ribosomal protein L11; Belongs to the methyltransferase superfamily. PrmA family. | 0.642 |
cbpA1 | rplK | HEAR1440 | HEAR3177 | Curved DNA-binding protein; Function of strongly homologous gene; factor. | 50S ribosomal subunit protein L11; Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. | 0.770 |
cbpA2 | HEAR0847 | HEAR1694 | HEAR0847 | Curved DNA-binding protein; Function of strongly homologous gene; factor. | Conserved hypothetical protein; Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit. | 0.440 |
cbpA2 | prmA | HEAR1694 | HEAR2764 | Curved DNA-binding protein; Function of strongly homologous gene; factor. | Ribosomal protein L11 methyltransferase (L11 Mtase); Methylates ribosomal protein L11; Belongs to the methyltransferase superfamily. PrmA family. | 0.642 |
cbpA2 | rplK | HEAR1694 | HEAR3177 | Curved DNA-binding protein; Function of strongly homologous gene; factor. | 50S ribosomal subunit protein L11; Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. | 0.770 |
dnaJ | HEAR0847 | HEAR2646 | HEAR0847 | Chaperone protein DnaJ; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, D [...] | Conserved hypothetical protein; Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit. | 0.479 |
dnaJ | prmA | HEAR2646 | HEAR2764 | Chaperone protein DnaJ; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, D [...] | Ribosomal protein L11 methyltransferase (L11 Mtase); Methylates ribosomal protein L11; Belongs to the methyltransferase superfamily. PrmA family. | 0.642 |
dnaJ | rplK | HEAR2646 | HEAR3177 | Chaperone protein DnaJ; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, D [...] | 50S ribosomal subunit protein L11; Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. | 0.770 |
pkfB | HEAR2765 | HEAR2766 | HEAR2765 | Carbohydrate kinase; Function of strongly homologous gene; enzyme. | Conserved hypothetical protein; Homologs of previously reported genes of unknown function. | 0.555 |