node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
Dcd | Psyr_2555 | Psyr_2556 | Psyr_2555 | dCTP deaminase. | (dCTP deaminase), deoxycytidine triphosphate deaminase. | 0.979 |
Dcd | dcd | Psyr_2556 | Psyr_3883 | dCTP deaminase. | dCTP deaminase; Catalyzes the deamination of dCTP to dUTP. | 0.900 |
Dcd | dut | Psyr_2556 | Psyr_0220 | dCTP deaminase. | Deoxyuridine 5'-triphosphate nucleotidohydrolase; This enzyme is involved in nucleotide metabolism: it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA; Belongs to the dUTPase family. | 0.914 |
Dcd | ndk | Psyr_2556 | Psyr_1244 | dCTP deaminase. | Nucleoside diphosphate kinase; Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate; Belongs to the NDK family. | 0.916 |
Psyr_0221 | dut | Psyr_0221 | Psyr_0220 | Phosphopantothenate-cysteine ligase / Phosphopantothenoylcysteine decarboxylase; Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4- phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine; In the C-terminal section; belongs to the PPC synthetase family. | Deoxyuridine 5'-triphosphate nucleotidohydrolase; This enzyme is involved in nucleotide metabolism: it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA; Belongs to the dUTPase family. | 0.966 |
Psyr_2075 | Psyr_4942 | Psyr_2075 | Psyr_4942 | 5-nucleotidase. | HAD-superfamily hydrolase, subfamily IA, variant 3. | 0.900 |
Psyr_2075 | dut | Psyr_2075 | Psyr_0220 | 5-nucleotidase. | Deoxyuridine 5'-triphosphate nucleotidohydrolase; This enzyme is involved in nucleotide metabolism: it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA; Belongs to the dUTPase family. | 0.900 |
Psyr_2075 | surE | Psyr_2075 | Psyr_1371 | 5-nucleotidase. | 5'-nucleotidase / exopolyphosphatase / 3'-nucleotidase; Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates; Belongs to the SurE nucleotidase family. | 0.900 |
Psyr_2075 | thyA | Psyr_2075 | Psyr_4840 | 5-nucleotidase. | Thymidylate synthase; Catalyzes the reductive methylation of 2'-deoxyuridine-5'- monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by- product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis. | 0.900 |
Psyr_2075 | tmk | Psyr_2075 | Psyr_1652 | 5-nucleotidase. | Thymidylate kinase; Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis; Belongs to the thymidylate kinase family. | 0.900 |
Psyr_2555 | Dcd | Psyr_2555 | Psyr_2556 | (dCTP deaminase), deoxycytidine triphosphate deaminase. | dCTP deaminase. | 0.979 |
Psyr_2555 | dcd | Psyr_2555 | Psyr_3883 | (dCTP deaminase), deoxycytidine triphosphate deaminase. | dCTP deaminase; Catalyzes the deamination of dCTP to dUTP. | 0.900 |
Psyr_2555 | dut | Psyr_2555 | Psyr_0220 | (dCTP deaminase), deoxycytidine triphosphate deaminase. | Deoxyuridine 5'-triphosphate nucleotidohydrolase; This enzyme is involved in nucleotide metabolism: it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA; Belongs to the dUTPase family. | 0.914 |
Psyr_2555 | ndk | Psyr_2555 | Psyr_1244 | (dCTP deaminase), deoxycytidine triphosphate deaminase. | Nucleoside diphosphate kinase; Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate; Belongs to the NDK family. | 0.916 |
Psyr_4942 | Psyr_2075 | Psyr_4942 | Psyr_2075 | HAD-superfamily hydrolase, subfamily IA, variant 3. | 5-nucleotidase. | 0.900 |
Psyr_4942 | dut | Psyr_4942 | Psyr_0220 | HAD-superfamily hydrolase, subfamily IA, variant 3. | Deoxyuridine 5'-triphosphate nucleotidohydrolase; This enzyme is involved in nucleotide metabolism: it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA; Belongs to the dUTPase family. | 0.900 |
Psyr_4942 | surE | Psyr_4942 | Psyr_1371 | HAD-superfamily hydrolase, subfamily IA, variant 3. | 5'-nucleotidase / exopolyphosphatase / 3'-nucleotidase; Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates; Belongs to the SurE nucleotidase family. | 0.910 |
Psyr_4942 | thyA | Psyr_4942 | Psyr_4840 | HAD-superfamily hydrolase, subfamily IA, variant 3. | Thymidylate synthase; Catalyzes the reductive methylation of 2'-deoxyuridine-5'- monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by- product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis. | 0.902 |
Psyr_4942 | tmk | Psyr_4942 | Psyr_1652 | HAD-superfamily hydrolase, subfamily IA, variant 3. | Thymidylate kinase; Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis; Belongs to the thymidylate kinase family. | 0.901 |
dcd | Dcd | Psyr_3883 | Psyr_2556 | dCTP deaminase; Catalyzes the deamination of dCTP to dUTP. | dCTP deaminase. | 0.900 |