node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
Psyr_1095 | Psyr_2011 | Psyr_1095 | Psyr_2011 | Glycine cleavage system T protein. | Dihydrolipoamide dehydrogenase. | 0.947 |
Psyr_1095 | gcvH | Psyr_1095 | Psyr_0247 | Glycine cleavage system T protein. | Glycine cleavage system H protein; The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein. | 0.997 |
Psyr_1095 | gcvH-2 | Psyr_1095 | Psyr_1097 | Glycine cleavage system T protein. | Glycine cleavage system H protein; The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein. | 0.998 |
Psyr_1095 | gcvP | Psyr_1095 | Psyr_1096 | Glycine cleavage system T protein. | Glycine dehydrogenase (decarboxylating); The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein; Belongs to the GcvP family. | 0.999 |
Psyr_1095 | gcvT | Psyr_1095 | Psyr_0246 | Glycine cleavage system T protein. | Aminomethyltransferase; The glycine cleavage system catalyzes the degradation of glycine. | 0.918 |
Psyr_1095 | glyA1 | Psyr_1095 | Psyr_4270 | Glycine cleavage system T protein. | Serine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. | 0.975 |
Psyr_1095 | glyA2 | Psyr_1095 | Psyr_4712 | Glycine cleavage system T protein. | Serine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. | 0.973 |
Psyr_2011 | Psyr_1095 | Psyr_2011 | Psyr_1095 | Dihydrolipoamide dehydrogenase. | Glycine cleavage system T protein. | 0.947 |
Psyr_2011 | Psyr_2222 | Psyr_2011 | Psyr_2222 | Dihydrolipoamide dehydrogenase. | Aminomethyltransferase; Belongs to the GcvT family. | 0.744 |
Psyr_2011 | Psyr_4031 | Psyr_2011 | Psyr_4031 | Dihydrolipoamide dehydrogenase. | Fumarase; Catalyzes the reversible hydration of fumarate to (S)-malate. Belongs to the class-I fumarase family. | 0.444 |
Psyr_2011 | Psyr_4715 | Psyr_2011 | Psyr_4715 | Dihydrolipoamide dehydrogenase. | Sarcosine oxidase, alpha subunit, heterotetrameric; Belongs to the GcvT family. | 0.744 |
Psyr_2011 | gcvH | Psyr_2011 | Psyr_0247 | Dihydrolipoamide dehydrogenase. | Glycine cleavage system H protein; The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein. | 0.972 |
Psyr_2011 | gcvH-2 | Psyr_2011 | Psyr_1097 | Dihydrolipoamide dehydrogenase. | Glycine cleavage system H protein; The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein. | 0.969 |
Psyr_2011 | gcvP | Psyr_2011 | Psyr_1096 | Dihydrolipoamide dehydrogenase. | Glycine dehydrogenase (decarboxylating); The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein; Belongs to the GcvP family. | 0.962 |
Psyr_2011 | gcvT | Psyr_2011 | Psyr_0246 | Dihydrolipoamide dehydrogenase. | Aminomethyltransferase; The glycine cleavage system catalyzes the degradation of glycine. | 0.943 |
Psyr_2011 | glyA1 | Psyr_2011 | Psyr_4270 | Dihydrolipoamide dehydrogenase. | Serine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. | 0.915 |
Psyr_2011 | glyA2 | Psyr_2011 | Psyr_4712 | Dihydrolipoamide dehydrogenase. | Serine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. | 0.915 |
Psyr_2222 | Psyr_2011 | Psyr_2222 | Psyr_2011 | Aminomethyltransferase; Belongs to the GcvT family. | Dihydrolipoamide dehydrogenase. | 0.744 |
Psyr_2222 | gcvH | Psyr_2222 | Psyr_0247 | Aminomethyltransferase; Belongs to the GcvT family. | Glycine cleavage system H protein; The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein. | 0.852 |
Psyr_2222 | gcvH-2 | Psyr_2222 | Psyr_1097 | Aminomethyltransferase; Belongs to the GcvT family. | Glycine cleavage system H protein; The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein. | 0.849 |