node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
IlvH | Psyr_0846 | Psyr_0847 | Psyr_0846 | Acetolactate synthase, small subunit. | Acetolactate synthase, large subunit. | 0.999 |
IlvH | Psyr_2314 | Psyr_0847 | Psyr_2314 | Acetolactate synthase, small subunit. | Pyruvate dehydrogenase (cytochrome); Belongs to the TPP enzyme family. | 0.983 |
IlvH | Psyr_2396 | Psyr_0847 | Psyr_2396 | Acetolactate synthase, small subunit. | Tartrate dehydrogenase. | 0.973 |
IlvH | Psyr_3071 | Psyr_0847 | Psyr_3071 | Acetolactate synthase, small subunit. | 3-isopropylmalate dehydrogenase. | 0.722 |
IlvH | ilvC | Psyr_0847 | Psyr_0848 | Acetolactate synthase, small subunit. | Ketol-acid reductoisomerase; Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol-acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3-dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3-hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate. | 0.999 |
IlvH | ilvD | Psyr_0847 | Psyr_0469 | Acetolactate synthase, small subunit. | Dihydroxyacid dehydratase; Belongs to the IlvD/Edd family. | 0.802 |
IlvH | leuA | Psyr_0847 | Psyr_1257 | Acetolactate synthase, small subunit. | 2-isopropylmalate synthase; Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3- hydroxy-4-methylpentanoate (2-isopropylmalate); Belongs to the alpha-IPM synthase/homocitrate synthase family. LeuA type 2 subfamily. | 0.934 |
IlvH | leuB | Psyr_0847 | Psyr_1985 | Acetolactate synthase, small subunit. | 3-isopropylmalate dehydrogenase; Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate. Belongs to the isocitrate and isopropylmalate dehydrogenases family. LeuB type 1 subfamily. | 0.982 |
IlvH | leuC | Psyr_0847 | Psyr_1983 | Acetolactate synthase, small subunit. | 3-isopropylmalate dehydratase, large subunit; Catalyzes the isomerization between 2-isopropylmalate and 3- isopropylmalate, via the formation of 2-isopropylmaleate. | 0.901 |
IlvH | leuD | Psyr_0847 | Psyr_1984 | Acetolactate synthase, small subunit. | 3-isopropylmalate dehydratase, small subunit; Catalyzes the isomerization between 2-isopropylmalate and 3- isopropylmalate, via the formation of 2-isopropylmaleate. Belongs to the LeuD family. LeuD type 1 subfamily. | 0.895 |
Psyr_0846 | IlvH | Psyr_0846 | Psyr_0847 | Acetolactate synthase, large subunit. | Acetolactate synthase, small subunit. | 0.999 |
Psyr_0846 | Psyr_2314 | Psyr_0846 | Psyr_2314 | Acetolactate synthase, large subunit. | Pyruvate dehydrogenase (cytochrome); Belongs to the TPP enzyme family. | 0.843 |
Psyr_0846 | Psyr_2396 | Psyr_0846 | Psyr_2396 | Acetolactate synthase, large subunit. | Tartrate dehydrogenase. | 0.961 |
Psyr_0846 | Psyr_3071 | Psyr_0846 | Psyr_3071 | Acetolactate synthase, large subunit. | 3-isopropylmalate dehydrogenase. | 0.702 |
Psyr_0846 | ilvC | Psyr_0846 | Psyr_0848 | Acetolactate synthase, large subunit. | Ketol-acid reductoisomerase; Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol-acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3-dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3-hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate. | 0.996 |
Psyr_0846 | ilvD | Psyr_0846 | Psyr_0469 | Acetolactate synthase, large subunit. | Dihydroxyacid dehydratase; Belongs to the IlvD/Edd family. | 0.901 |
Psyr_0846 | leuA | Psyr_0846 | Psyr_1257 | Acetolactate synthase, large subunit. | 2-isopropylmalate synthase; Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3- hydroxy-4-methylpentanoate (2-isopropylmalate); Belongs to the alpha-IPM synthase/homocitrate synthase family. LeuA type 2 subfamily. | 0.895 |
Psyr_0846 | leuB | Psyr_0846 | Psyr_1985 | Acetolactate synthase, large subunit. | 3-isopropylmalate dehydrogenase; Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate. Belongs to the isocitrate and isopropylmalate dehydrogenases family. LeuB type 1 subfamily. | 0.982 |
Psyr_0846 | leuC | Psyr_0846 | Psyr_1983 | Acetolactate synthase, large subunit. | 3-isopropylmalate dehydratase, large subunit; Catalyzes the isomerization between 2-isopropylmalate and 3- isopropylmalate, via the formation of 2-isopropylmaleate. | 0.837 |
Psyr_0846 | leuD | Psyr_0846 | Psyr_1984 | Acetolactate synthase, large subunit. | 3-isopropylmalate dehydratase, small subunit; Catalyzes the isomerization between 2-isopropylmalate and 3- isopropylmalate, via the formation of 2-isopropylmaleate. Belongs to the LeuD family. LeuD type 1 subfamily. | 0.846 |