node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
Psyr_0061 | Psyr_2098 | Psyr_0061 | Psyr_2098 | uroporphyrinogen-III synthase; Catalyzes cyclization of the linear tetrapyrrole, hydroxymethylbilane, to the macrocyclic uroporphyrinogen III. | uroporphyrinogen-III C-methyltransferase; Belongs to the precorrin methyltransferase family. | 0.924 |
Psyr_0061 | cysG | Psyr_0061 | Psyr_3174 | uroporphyrinogen-III synthase; Catalyzes cyclization of the linear tetrapyrrole, hydroxymethylbilane, to the macrocyclic uroporphyrinogen III. | uroporphyrinogen-III C-methyltransferase / precorrin-2 dehydrogenase; Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD-dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme. | 0.964 |
Psyr_0061 | cysN | Psyr_0061 | Psyr_4126 | uroporphyrinogen-III synthase; Catalyzes cyclization of the linear tetrapyrrole, hydroxymethylbilane, to the macrocyclic uroporphyrinogen III. | Adenylylsulfate kinase / sulfate adenylyltransferase subunit 1; May be the GTPase, regulating ATP sulfurylase activity. Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. CysN/NodQ subfamily. | 0.564 |
Psyr_0061 | hemC | Psyr_0061 | Psyr_0062 | uroporphyrinogen-III synthase; Catalyzes cyclization of the linear tetrapyrrole, hydroxymethylbilane, to the macrocyclic uroporphyrinogen III. | Hydroxymethylbilane synthase; Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps. Belongs to the HMBS family. | 0.997 |
Psyr_0061 | hemE | Psyr_0061 | Psyr_0414 | uroporphyrinogen-III synthase; Catalyzes cyclization of the linear tetrapyrrole, hydroxymethylbilane, to the macrocyclic uroporphyrinogen III. | Uroporphyrinogen decarboxylase; Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III. | 0.939 |
Psyr_2078 | Psyr_2098 | Psyr_2078 | Psyr_2098 | Phosphoadenylylsulfate reductase (thioredoxin); Reduction of activated sulfate into sulfite. | uroporphyrinogen-III C-methyltransferase; Belongs to the precorrin methyltransferase family. | 0.697 |
Psyr_2078 | Psyr_2462 | Psyr_2078 | Psyr_2462 | Phosphoadenylylsulfate reductase (thioredoxin); Reduction of activated sulfate into sulfite. | Nitrite/sulfite reductase, hemoprotein beta-component, ferrodoxin-like:Nitrite and sulphite reductase 4Fe-4S region. | 0.998 |
Psyr_2078 | Psyr_4417 | Psyr_2078 | Psyr_4417 | Phosphoadenylylsulfate reductase (thioredoxin); Reduction of activated sulfate into sulfite. | Ferredoxin--nitrite reductase. | 0.853 |
Psyr_2078 | cysD | Psyr_2078 | Psyr_4128 | Phosphoadenylylsulfate reductase (thioredoxin); Reduction of activated sulfate into sulfite. | Sulfate adenylyltransferase subunit 2. | 0.960 |
Psyr_2078 | cysG | Psyr_2078 | Psyr_3174 | Phosphoadenylylsulfate reductase (thioredoxin); Reduction of activated sulfate into sulfite. | uroporphyrinogen-III C-methyltransferase / precorrin-2 dehydrogenase; Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD-dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme. | 0.926 |
Psyr_2078 | cysN | Psyr_2078 | Psyr_4126 | Phosphoadenylylsulfate reductase (thioredoxin); Reduction of activated sulfate into sulfite. | Adenylylsulfate kinase / sulfate adenylyltransferase subunit 1; May be the GTPase, regulating ATP sulfurylase activity. Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. CysN/NodQ subfamily. | 0.999 |
Psyr_2098 | Psyr_0061 | Psyr_2098 | Psyr_0061 | uroporphyrinogen-III C-methyltransferase; Belongs to the precorrin methyltransferase family. | uroporphyrinogen-III synthase; Catalyzes cyclization of the linear tetrapyrrole, hydroxymethylbilane, to the macrocyclic uroporphyrinogen III. | 0.924 |
Psyr_2098 | Psyr_2078 | Psyr_2098 | Psyr_2078 | uroporphyrinogen-III C-methyltransferase; Belongs to the precorrin methyltransferase family. | Phosphoadenylylsulfate reductase (thioredoxin); Reduction of activated sulfate into sulfite. | 0.697 |
Psyr_2098 | Psyr_2462 | Psyr_2098 | Psyr_2462 | uroporphyrinogen-III C-methyltransferase; Belongs to the precorrin methyltransferase family. | Nitrite/sulfite reductase, hemoprotein beta-component, ferrodoxin-like:Nitrite and sulphite reductase 4Fe-4S region. | 0.695 |
Psyr_2098 | Psyr_4415 | Psyr_2098 | Psyr_4415 | uroporphyrinogen-III C-methyltransferase; Belongs to the precorrin methyltransferase family. | Cobalt-factor II C20-methyltransferase / precorrin-2 C20-methyltransferase; Methylates precorrin-2 at the C-20 position to produce precorrin-3A. | 0.933 |
Psyr_2098 | Psyr_4417 | Psyr_2098 | Psyr_4417 | uroporphyrinogen-III C-methyltransferase; Belongs to the precorrin methyltransferase family. | Ferredoxin--nitrite reductase. | 0.688 |
Psyr_2098 | cysD | Psyr_2098 | Psyr_4128 | uroporphyrinogen-III C-methyltransferase; Belongs to the precorrin methyltransferase family. | Sulfate adenylyltransferase subunit 2. | 0.569 |
Psyr_2098 | cysG | Psyr_2098 | Psyr_3174 | uroporphyrinogen-III C-methyltransferase; Belongs to the precorrin methyltransferase family. | uroporphyrinogen-III C-methyltransferase / precorrin-2 dehydrogenase; Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD-dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme. | 0.957 |
Psyr_2098 | cysN | Psyr_2098 | Psyr_4126 | uroporphyrinogen-III C-methyltransferase; Belongs to the precorrin methyltransferase family. | Adenylylsulfate kinase / sulfate adenylyltransferase subunit 1; May be the GTPase, regulating ATP sulfurylase activity. Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. CysN/NodQ subfamily. | 0.798 |
Psyr_2098 | hemC | Psyr_2098 | Psyr_0062 | uroporphyrinogen-III C-methyltransferase; Belongs to the precorrin methyltransferase family. | Hydroxymethylbilane synthase; Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps. Belongs to the HMBS family. | 0.981 |