node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
ECH_0029 | hemE | ECH_0029 | ECH_0030 | Cytochrome c oxidase, subunit III; Identified by match to protein family HMM PF00510. | Uroporphyrinogen decarboxylase; Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III. | 0.911 |
ECH_0029 | ruvC | ECH_0029 | ECH_0028 | Cytochrome c oxidase, subunit III; Identified by match to protein family HMM PF00510. | Crossover junction endodeoxyribonuclease RuvC; Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group. | 0.832 |
ECH_0653 | ECH_0746 | ECH_0653 | ECH_0746 | Ankyrin repeat protein; Identified by match to protein family HMM PF00023. | Topoisomerase DNA-binding C4 zinc finger domain protein; Identified by similarity to SP:P73810; match to protein family HMM PF01396. | 0.970 |
ECH_0653 | polA | ECH_0653 | ECH_0080 | Ankyrin repeat protein; Identified by match to protein family HMM PF00023. | DNA polymerase I; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity; Belongs to the DNA polymerase type-A family. | 0.986 |
ECH_0653 | recA | ECH_0653 | ECH_1109 | Ankyrin repeat protein; Identified by match to protein family HMM PF00023. | recA protein; Can catalyze the hydrolysis of ATP in the presence of single- stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage; Belongs to the RecA family. | 0.985 |
ECH_0653 | recJ | ECH_0653 | ECH_1115 | Ankyrin repeat protein; Identified by match to protein family HMM PF00023. | single-stranded-DNA-specific exonuclease RecJ; Identified by match to protein family HMM PF01368; match to protein family HMM PF02272; match to protein family HMM TIGR00644. | 0.477 |
ECH_0653 | ruvA | ECH_0653 | ECH_0320 | Ankyrin repeat protein; Identified by match to protein family HMM PF00023. | Holliday junction DNA helicase RuvA; The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB. | 0.410 |
ECH_0653 | ruvB | ECH_0653 | ECH_0319 | Ankyrin repeat protein; Identified by match to protein family HMM PF00023. | Holliday junction DNA helicase RuvB; The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. | 0.448 |
ECH_0653 | ruvC | ECH_0653 | ECH_0028 | Ankyrin repeat protein; Identified by match to protein family HMM PF00023. | Crossover junction endodeoxyribonuclease RuvC; Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group. | 0.537 |
ECH_0653 | topA | ECH_0653 | ECH_0750 | Ankyrin repeat protein; Identified by match to protein family HMM PF00023. | DNA topoisomerase I; Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA- (5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supe [...] | 0.970 |
ECH_0746 | ECH_0653 | ECH_0746 | ECH_0653 | Topoisomerase DNA-binding C4 zinc finger domain protein; Identified by similarity to SP:P73810; match to protein family HMM PF01396. | Ankyrin repeat protein; Identified by match to protein family HMM PF00023. | 0.970 |
ECH_0746 | polA | ECH_0746 | ECH_0080 | Topoisomerase DNA-binding C4 zinc finger domain protein; Identified by similarity to SP:P73810; match to protein family HMM PF01396. | DNA polymerase I; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity; Belongs to the DNA polymerase type-A family. | 0.891 |
ECH_0746 | recA | ECH_0746 | ECH_1109 | Topoisomerase DNA-binding C4 zinc finger domain protein; Identified by similarity to SP:P73810; match to protein family HMM PF01396. | recA protein; Can catalyze the hydrolysis of ATP in the presence of single- stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage; Belongs to the RecA family. | 0.878 |
ECH_0746 | recJ | ECH_0746 | ECH_1115 | Topoisomerase DNA-binding C4 zinc finger domain protein; Identified by similarity to SP:P73810; match to protein family HMM PF01396. | single-stranded-DNA-specific exonuclease RecJ; Identified by match to protein family HMM PF01368; match to protein family HMM PF02272; match to protein family HMM TIGR00644. | 0.525 |
ECH_0746 | ruvA | ECH_0746 | ECH_0320 | Topoisomerase DNA-binding C4 zinc finger domain protein; Identified by similarity to SP:P73810; match to protein family HMM PF01396. | Holliday junction DNA helicase RuvA; The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB. | 0.474 |
ECH_0746 | ruvB | ECH_0746 | ECH_0319 | Topoisomerase DNA-binding C4 zinc finger domain protein; Identified by similarity to SP:P73810; match to protein family HMM PF01396. | Holliday junction DNA helicase RuvB; The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. | 0.466 |
ECH_0746 | ruvC | ECH_0746 | ECH_0028 | Topoisomerase DNA-binding C4 zinc finger domain protein; Identified by similarity to SP:P73810; match to protein family HMM PF01396. | Crossover junction endodeoxyribonuclease RuvC; Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group. | 0.493 |
hemE | ECH_0029 | ECH_0030 | ECH_0029 | Uroporphyrinogen decarboxylase; Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III. | Cytochrome c oxidase, subunit III; Identified by match to protein family HMM PF00510. | 0.911 |
hemE | polA | ECH_0030 | ECH_0080 | Uroporphyrinogen decarboxylase; Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III. | DNA polymerase I; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity; Belongs to the DNA polymerase type-A family. | 0.661 |
hemE | recA | ECH_0030 | ECH_1109 | Uroporphyrinogen decarboxylase; Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III. | recA protein; Can catalyze the hydrolysis of ATP in the presence of single- stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage; Belongs to the RecA family. | 0.449 |