STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
AKF24080.1Ribosomal protein S12 methylthiotransferase; Derived by automated computational analysis using gene prediction method: Protein Homology. (440 aa)    
Predicted Functional Partners:
rlmN
50S rRNA methyltransferase; Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs. m2A2503 modification seems to play a crucial role in the proofreading step occurring at the peptidyl transferase center and thus would serve to optimize ribosomal fidelity; Belongs to the radical SAM superfamily. RlmN family.
 
  
 0.709
AKF24853.1
glutamate--tRNA ligase; Catalyzes a two-step reaction, first charging a glutamine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; in Deinococcus the extra C-terminal extension of YqeY domain enhances affinity for tRNA-Gln; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
  
 0.580
AKF24079.1
tRNA(Ile)-lysidine synthetase; Derived by automated computational analysis using gene prediction method: Protein Homology.
     
 0.566
AKF24818.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
    0.515
AKF24824.1
Signal peptidase; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
    0.515
AKF25424.1
Sodium:proton antiporter; Binds and transfers iron-sulfur (Fe-S) clusters to target apoproteins. Can hydrolyze ATP; Belongs to the Mrp/NBP35 ATP-binding proteins family.
  
   
 0.512
AKF25964.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
    0.493
AKF25967.1
tRNA s(4)U8 sulfurtransferase; Catalyzes the conversion of uridine to 4-thiouridinine tRNA; also required for the synthesis of the thiazole moiety; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
  
 0.471
AKF24524.1
ATPase; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
   
 0.468
truB
tRNA pseudouridine synthase B; Catalyzes isomerization of specific uridines in RNA to pseudouridine; responsible for residues in T loops of many tRNAs; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
  
 0.459
Your Current Organism:
Sulfurovum lithotrophicum
NCBI taxonomy Id: 206403
Other names: ATCC BAA-797, JCM 12117, S. lithotrophicum, Sulfurovum lithotrophicum Inagaki et al. 2004, epsilon proteobacterium 42BKT, strain 42BKT
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