STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
AKF25542.1ATP-dependent DNA helicase; Derived by automated computational analysis using gene prediction method: Protein Homology. (688 aa)    
Predicted Functional Partners:
AKF24948.1
ATP-dependent DNA helicase; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
  
 
0.927
recQ
ATP-dependent DNA helicase RecQ; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
 
 0.845
uvrB
Excinuclease ABC subunit B; The UvrABC repair system catalyzes the recognition and processing of DNA lesions. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. Upon binding of the UvrA(2)B(2) complex to a putative damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate [...]
 
 
 0.838
truB
tRNA pseudouridine synthase B; Catalyzes isomerization of specific uridines in RNA to pseudouridine; responsible for residues in T loops of many tRNAs; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
  
 0.828
AKF23971.1
DNA polymerase III subunit beta; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
 
 0.799
AKF25725.1
Recombinase RecA; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
 
 0.793
AKF25544.1
4-diphosphocytidyl-2C-methyl-D-erythritol kinase; Derived by automated computational analysis using gene prediction method: Protein Homology.
       0.772
AKF24400.1
Excinuclease ABC subunit C; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
  
 0.742
AKF24370.1
UTP--glucose-1-phosphate uridylyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology.
      0.672
AKF24133.1
DNA topoisomerase I; Catalyzes the ATP-dependent breakage of single-stranded DNA followed by passage and rejoining, maintains net negative superhelicity; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
 
 0.667
Your Current Organism:
Sulfurovum lithotrophicum
NCBI taxonomy Id: 206403
Other names: ATCC BAA-797, JCM 12117, S. lithotrophicum, Sulfurovum lithotrophicum Inagaki et al. 2004, epsilon proteobacterium 42BKT, strain 42BKT
Server load: low (28%) [HD]