node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
BL0726 | BL0730 | BL0726 | BL0730 | Widely conserved hypothetical protein in upf102; COG family: uncharacterized Acr; PFAM_ID: DUF28. | Hypothetical protein with duf129; COG family: preprotein translocase subunit YajC; PFAM_ID: DUF219. | 0.669 |
BL0726 | ruvA | BL0726 | BL0728 | Widely conserved hypothetical protein in upf102; COG family: uncharacterized Acr; PFAM_ID: DUF28. | Probable holliday junction DNA helicase RuvA; The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB. | 0.795 |
BL0726 | ruvB | BL0726 | BL0729 | Widely conserved hypothetical protein in upf102; COG family: uncharacterized Acr; PFAM_ID: DUF28. | Holliday junction DNA helicase RuvB; The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. | 0.800 |
BL0726 | ruvC | BL0726 | BL0727 | Widely conserved hypothetical protein in upf102; COG family: uncharacterized Acr; PFAM_ID: DUF28. | Crossover junction endodeoxyribonuclease RuvC; Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group. | 0.890 |
BL0730 | BL0726 | BL0730 | BL0726 | Hypothetical protein with duf129; COG family: preprotein translocase subunit YajC; PFAM_ID: DUF219. | Widely conserved hypothetical protein in upf102; COG family: uncharacterized Acr; PFAM_ID: DUF28. | 0.669 |
BL0730 | polA | BL0730 | BL0985 | Hypothetical protein with duf129; COG family: preprotein translocase subunit YajC; PFAM_ID: DUF219. | DNA polymerase I; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity; Belongs to the DNA polymerase type-A family. | 0.405 |
BL0730 | ruvA | BL0730 | BL0728 | Hypothetical protein with duf129; COG family: preprotein translocase subunit YajC; PFAM_ID: DUF219. | Probable holliday junction DNA helicase RuvA; The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB. | 0.733 |
BL0730 | ruvB | BL0730 | BL0729 | Hypothetical protein with duf129; COG family: preprotein translocase subunit YajC; PFAM_ID: DUF219. | Holliday junction DNA helicase RuvB; The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. | 0.739 |
BL0730 | ruvC | BL0730 | BL0727 | Hypothetical protein with duf129; COG family: preprotein translocase subunit YajC; PFAM_ID: DUF219. | Crossover junction endodeoxyribonuclease RuvC; Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group. | 0.664 |
BL1416 | polA | BL1416 | BL0985 | RecX-like protein; Modulates RecA activity; Belongs to the RecX family. | DNA polymerase I; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity; Belongs to the DNA polymerase type-A family. | 0.505 |
BL1416 | recA | BL1416 | BL1415 | RecX-like protein; Modulates RecA activity; Belongs to the RecX family. | RecA protein; Can catalyze the hydrolysis of ATP in the presence of single- stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage; Belongs to the RecA family. | 0.999 |
BL1416 | recN | BL1416 | BL1043 | RecX-like protein; Modulates RecA activity; Belongs to the RecX family. | DNA repair protein RecN; May be involved in recombinational repair of damaged DNA. | 0.754 |
BL1416 | recO | BL1416 | BL0100 | RecX-like protein; Modulates RecA activity; Belongs to the RecX family. | Hypothetical protein; Involved in DNA repair and RecF pathway recombination. | 0.714 |
BL1416 | ruvA | BL1416 | BL0728 | RecX-like protein; Modulates RecA activity; Belongs to the RecX family. | Probable holliday junction DNA helicase RuvA; The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB. | 0.646 |
BL1416 | ruvB | BL1416 | BL0729 | RecX-like protein; Modulates RecA activity; Belongs to the RecX family. | Holliday junction DNA helicase RuvB; The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. | 0.654 |
BL1416 | ruvC | BL1416 | BL0727 | RecX-like protein; Modulates RecA activity; Belongs to the RecX family. | Crossover junction endodeoxyribonuclease RuvC; Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group. | 0.811 |
polA | BL0730 | BL0985 | BL0730 | DNA polymerase I; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity; Belongs to the DNA polymerase type-A family. | Hypothetical protein with duf129; COG family: preprotein translocase subunit YajC; PFAM_ID: DUF219. | 0.405 |
polA | BL1416 | BL0985 | BL1416 | DNA polymerase I; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity; Belongs to the DNA polymerase type-A family. | RecX-like protein; Modulates RecA activity; Belongs to the RecX family. | 0.505 |
polA | recA | BL0985 | BL1415 | DNA polymerase I; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity; Belongs to the DNA polymerase type-A family. | RecA protein; Can catalyze the hydrolysis of ATP in the presence of single- stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage; Belongs to the RecA family. | 0.999 |
polA | recN | BL0985 | BL1043 | DNA polymerase I; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity; Belongs to the DNA polymerase type-A family. | DNA repair protein RecN; May be involved in recombinational repair of damaged DNA. | 0.604 |