STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
folEGTP-ch-I; FolE; COG family: GTP cyclohydrolase I; PFAM_ID: GTP_cyclohydroI. (199 aa)    
Predicted Functional Partners:
folP
Dihydropteroate synthase 1; Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8- dihydropteroate (H2Pte), the immediate precursor of folate derivatives.
  
 0.999
sulD
SulD; Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin.
 
  
 0.999
ftsH
ATP-dependent zinc metallopeptidase involved in cell division; Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins; Belongs to the AAA ATPase family. In the central section; belongs to the AAA ATPase family.
  
  
 0.891
pyk
Pyk; COG family: pyruvate kinase; PFAM_ID: PK; PFAM_ID: PK_C; Belongs to the pyruvate kinase family.
    
  0.807
nrdD
NrdD; COG family: oxygen-sensitive ribonucleoside-triphosphate reductase; PFAM_ID: Gly_radical.
    
  0.801
BL1407
Narrowly conserved hypothetical protein; COG family: uncharacterized Bcr.
     
  0.800
relA
RelA; In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance.
     
  0.800
folC
FolC or FpgS; COG family: folylpolyglutamate synthase; PFAM_ID: Mur_ligase; PFAM_ID: Mur_ligase; PFAM_ID: Mur_ligase_C.
  
  
 0.779
tilS
Narrowly conserved hypothetical protein similar to MesJ; Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine. Belongs to the tRNA(Ile)-lysidine synthase family.
     
 0.736
hprT
HgpRT; HprT; COG family: hypoxanthine-guanine phosphoribosyltransferase; PFAM_ID: Pribosyltran; Belongs to the purine/pyrimidine phosphoribosyltransferase family.
  
    0.714
Your Current Organism:
Bifidobacterium longum
NCBI taxonomy Id: 206672
Other names: B. longum NCC2705, Bifidobacterium longum NCC2705, Bifidobacterium longum str. NCC2705
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.