STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Dde_1273PFAM: Pyruvate formate-lyase, PFL; Formate C-acetyltransferase glycine radical; KEGG: dvu:DVU2824 formate acetyltransferase. (829 aa)    
Predicted Functional Partners:
Dde_1272
SMART: Elongator protein 3/MiaB/NifB; TIGRFAM: Glycyl radical enzyme-activating; KEGG: dvl:Dvul_0490 glycyl-radical activating family protein; PFAM: Radical SAM; 4Fe-4S ferredoxin, iron-sulphur binding, subgroup.
 
  
 0.968
Dde_3054
Glycyl-radical enzyme activating protein family; TIGRFAM: Glycyl radical enzyme-activating; KEGG: pth:PTH_2421 pyruvate-formate lyase-activating enzyme; PFAM: Radical SAM; 4Fe-4S ferredoxin, iron-sulphur binding, subgroup.
 
  
 0.894
cutD
Glycyl-radical enzyme activating protein family; Catalyzes activation of the choline trimethylamine-lyase CutC under anaerobic conditions by generation of an organic free radical on a glycine residue, via a homolytic cleavage of S-adenosyl-L-methionine (SAM). Is involved in the anaerobic choline utilization pathway that allows D.alaskensis to grow on choline as a source of carbon and energy; Belongs to the organic radical-activating enzymes family.
 
  
 0.894
Dde_1275
KEGG: dvl:Dvul_0493 TRAP dicarboxylate transporter, DctP subunit; TIGRFAM: TRAP dicarboxylate transporter, DctP subunit; PFAM: Extracellular solute-binding protein, family 7, bacteria.
 
  
 0.801
Dde_3237
SMART: Pyruvate-flavodoxin oxidoreductase, EKR domain; TIGRFAM: Pyruvate-flavodoxin oxidoreductase; KEGG: dvl:Dvul_0348 pyruvate flavodoxin/ferredoxin oxidoreductase domain-containing protein; PFAM: Pyruvate flavodoxin/ferredoxin oxidoreductase, N-terminal; Pyruvate-flavodoxin oxidoreductase, EKR domain; 4Fe-4S ferredoxin, iron-sulphur binding, subgroup; Thiamine pyrophosphate enzyme, C-terminal TPP-binding; Pyruvate/ketoisovalerate oxidoreductase; Belongs to the pyruvate:ferredoxin/flavodoxin oxidoreductase family.
     
 0.651
Dde_1274
KEGG: dvl:Dvul_0492 TRAP dicarboxylate transporter, DctM subunit; TIGRFAM: TRAP dicarboxylate transporter, DctM subunit; PFAM: TRAP C4-dicarboxylate transport system permease DctM subunit; Tripartite ATP-independent periplasmic transporter, DctQ component.
 
   
 0.622
Dde_1278
PFAM: Amidohydrolase 2; KEGG: dvl:Dvul_0495 amidohydrolase 2.
  
   
 0.556
Dde_0278
Anaerobic ribonucleoside-triphosphate reductase activating enzyme; PFAM: Radical SAM; KEGG: dvm:DvMF_1818 radical SAM domain protein.
  
  
 0.528
Dde_1670
KEGG: drt:Dret_0731 radical SAM domain-containing protein; PFAM: Radical SAM; SMART: Elongator protein 3/MiaB/NifB.
  
  
 0.528
tpiA
Triosephosphate isomerase; Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D- glyceraldehyde-3-phosphate (G3P); Belongs to the triosephosphate isomerase family.
   
 
 0.463
Your Current Organism:
Desulfovibrio alaskensis
NCBI taxonomy Id: 207559
Other names: D. alaskensis G20, Desulfovibrio alaskensis G20, Desulfovibrio alaskensis str. G20, Desulfovibrio alaskensis strain G20, Desulfovibrio desulfuricans subsp. desulfuricans str. G20
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