node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
Dde_0547 | Dde_2715 | Dde_0547 | Dde_2715 | TIGRFAM: ComEC/Rec2-related protein; PFAM: ComEC/Rec2-related protein; KEGG: das:Daes_1194 DNA internalization-like competence protein ComEC/Rec2; SMART: Beta-lactamase-like. | KEGG: dvm:DvMF_1134 single-stranded-DNA-specific exonuclease RecJ; TIGRFAM: Bacterial RecJ exonuclease; PFAM: Phosphoesterase, RecJ-like; Phosphoesterase, DHHA1. | 0.749 |
Dde_0547 | recA | Dde_0547 | Dde_2373 | TIGRFAM: ComEC/Rec2-related protein; PFAM: ComEC/Rec2-related protein; KEGG: das:Daes_1194 DNA internalization-like competence protein ComEC/Rec2; SMART: Beta-lactamase-like. | recA protein; Can catalyze the hydrolysis of ATP in the presence of single- stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage; Belongs to the RecA family. | 0.720 |
Dde_0547 | ruvA | Dde_0547 | Dde_2323 | TIGRFAM: ComEC/Rec2-related protein; PFAM: ComEC/Rec2-related protein; KEGG: das:Daes_1194 DNA internalization-like competence protein ComEC/Rec2; SMART: Beta-lactamase-like. | Holliday junction DNA helicase RuvA; The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB. | 0.599 |
Dde_0547 | ruvB | Dde_0547 | Dde_2322 | TIGRFAM: ComEC/Rec2-related protein; PFAM: ComEC/Rec2-related protein; KEGG: das:Daes_1194 DNA internalization-like competence protein ComEC/Rec2; SMART: Beta-lactamase-like. | Holliday junction DNA helicase RuvB; The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. | 0.622 |
Dde_0547 | ruvC | Dde_0547 | Dde_2324 | TIGRFAM: ComEC/Rec2-related protein; PFAM: ComEC/Rec2-related protein; KEGG: das:Daes_1194 DNA internalization-like competence protein ComEC/Rec2; SMART: Beta-lactamase-like. | Crossover junction endodeoxyribonuclease RuvC; Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group. | 0.543 |
Dde_2196 | Dde_2325 | Dde_2196 | Dde_2325 | DNA polymerase III, alpha subunit; SMART: Polymerase/histidinol phosphatase, N-terminal; TIGRFAM: DNA polymerase III, alpha subunit; KEGG: dvm:DvMF_0130 DNA polymerase III, alpha subunit; PFAM: Bacterial DNA polymerase III, alpha subunit; Nucleic acid binding, OB-fold, tRNA/helicase-type; PHP, C-terminal. | Protein of unknown function DUF28; KEGG: dvm:DvMF_3201 hypothetical protein; TIGRFAM: Protein of unknown function DUF28; PFAM: Protein of unknown function DUF28. | 0.449 |
Dde_2196 | polA | Dde_2196 | Dde_3450 | DNA polymerase III, alpha subunit; SMART: Polymerase/histidinol phosphatase, N-terminal; TIGRFAM: DNA polymerase III, alpha subunit; KEGG: dvm:DvMF_0130 DNA polymerase III, alpha subunit; PFAM: Bacterial DNA polymerase III, alpha subunit; Nucleic acid binding, OB-fold, tRNA/helicase-type; PHP, C-terminal. | DNA polymerase I; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity; Belongs to the DNA polymerase type-A family. | 0.751 |
Dde_2196 | recA | Dde_2196 | Dde_2373 | DNA polymerase III, alpha subunit; SMART: Polymerase/histidinol phosphatase, N-terminal; TIGRFAM: DNA polymerase III, alpha subunit; KEGG: dvm:DvMF_0130 DNA polymerase III, alpha subunit; PFAM: Bacterial DNA polymerase III, alpha subunit; Nucleic acid binding, OB-fold, tRNA/helicase-type; PHP, C-terminal. | recA protein; Can catalyze the hydrolysis of ATP in the presence of single- stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage; Belongs to the RecA family. | 0.606 |
Dde_2196 | ruvA | Dde_2196 | Dde_2323 | DNA polymerase III, alpha subunit; SMART: Polymerase/histidinol phosphatase, N-terminal; TIGRFAM: DNA polymerase III, alpha subunit; KEGG: dvm:DvMF_0130 DNA polymerase III, alpha subunit; PFAM: Bacterial DNA polymerase III, alpha subunit; Nucleic acid binding, OB-fold, tRNA/helicase-type; PHP, C-terminal. | Holliday junction DNA helicase RuvA; The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB. | 0.540 |
Dde_2196 | ruvB | Dde_2196 | Dde_2322 | DNA polymerase III, alpha subunit; SMART: Polymerase/histidinol phosphatase, N-terminal; TIGRFAM: DNA polymerase III, alpha subunit; KEGG: dvm:DvMF_0130 DNA polymerase III, alpha subunit; PFAM: Bacterial DNA polymerase III, alpha subunit; Nucleic acid binding, OB-fold, tRNA/helicase-type; PHP, C-terminal. | Holliday junction DNA helicase RuvB; The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. | 0.542 |
Dde_2196 | ruvC | Dde_2196 | Dde_2324 | DNA polymerase III, alpha subunit; SMART: Polymerase/histidinol phosphatase, N-terminal; TIGRFAM: DNA polymerase III, alpha subunit; KEGG: dvm:DvMF_0130 DNA polymerase III, alpha subunit; PFAM: Bacterial DNA polymerase III, alpha subunit; Nucleic acid binding, OB-fold, tRNA/helicase-type; PHP, C-terminal. | Crossover junction endodeoxyribonuclease RuvC; Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group. | 0.474 |
Dde_2196 | topA | Dde_2196 | Dde_0106 | DNA polymerase III, alpha subunit; SMART: Polymerase/histidinol phosphatase, N-terminal; TIGRFAM: DNA polymerase III, alpha subunit; KEGG: dvm:DvMF_0130 DNA polymerase III, alpha subunit; PFAM: Bacterial DNA polymerase III, alpha subunit; Nucleic acid binding, OB-fold, tRNA/helicase-type; PHP, C-terminal. | DNA topoisomerase I; Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA- (5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supe [...] | 0.678 |
Dde_2325 | Dde_2196 | Dde_2325 | Dde_2196 | Protein of unknown function DUF28; KEGG: dvm:DvMF_3201 hypothetical protein; TIGRFAM: Protein of unknown function DUF28; PFAM: Protein of unknown function DUF28. | DNA polymerase III, alpha subunit; SMART: Polymerase/histidinol phosphatase, N-terminal; TIGRFAM: DNA polymerase III, alpha subunit; KEGG: dvm:DvMF_0130 DNA polymerase III, alpha subunit; PFAM: Bacterial DNA polymerase III, alpha subunit; Nucleic acid binding, OB-fold, tRNA/helicase-type; PHP, C-terminal. | 0.449 |
Dde_2325 | ruvA | Dde_2325 | Dde_2323 | Protein of unknown function DUF28; KEGG: dvm:DvMF_3201 hypothetical protein; TIGRFAM: Protein of unknown function DUF28; PFAM: Protein of unknown function DUF28. | Holliday junction DNA helicase RuvA; The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB. | 0.580 |
Dde_2325 | ruvB | Dde_2325 | Dde_2322 | Protein of unknown function DUF28; KEGG: dvm:DvMF_3201 hypothetical protein; TIGRFAM: Protein of unknown function DUF28; PFAM: Protein of unknown function DUF28. | Holliday junction DNA helicase RuvB; The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. | 0.651 |
Dde_2325 | ruvC | Dde_2325 | Dde_2324 | Protein of unknown function DUF28; KEGG: dvm:DvMF_3201 hypothetical protein; TIGRFAM: Protein of unknown function DUF28; PFAM: Protein of unknown function DUF28. | Crossover junction endodeoxyribonuclease RuvC; Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group. | 0.735 |
Dde_2325 | thyX | Dde_2325 | Dde_2321 | Protein of unknown function DUF28; KEGG: dvm:DvMF_3201 hypothetical protein; TIGRFAM: Protein of unknown function DUF28; PFAM: Protein of unknown function DUF28. | Thymidylate synthase, flavin-dependent; Catalyzes the reductive methylation of 2'-deoxyuridine-5'- monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor, and NADPH and FADH(2) as the reductant. | 0.401 |
Dde_2715 | Dde_0547 | Dde_2715 | Dde_0547 | KEGG: dvm:DvMF_1134 single-stranded-DNA-specific exonuclease RecJ; TIGRFAM: Bacterial RecJ exonuclease; PFAM: Phosphoesterase, RecJ-like; Phosphoesterase, DHHA1. | TIGRFAM: ComEC/Rec2-related protein; PFAM: ComEC/Rec2-related protein; KEGG: das:Daes_1194 DNA internalization-like competence protein ComEC/Rec2; SMART: Beta-lactamase-like. | 0.749 |
Dde_2715 | polA | Dde_2715 | Dde_3450 | KEGG: dvm:DvMF_1134 single-stranded-DNA-specific exonuclease RecJ; TIGRFAM: Bacterial RecJ exonuclease; PFAM: Phosphoesterase, RecJ-like; Phosphoesterase, DHHA1. | DNA polymerase I; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity; Belongs to the DNA polymerase type-A family. | 0.578 |
Dde_2715 | recA | Dde_2715 | Dde_2373 | KEGG: dvm:DvMF_1134 single-stranded-DNA-specific exonuclease RecJ; TIGRFAM: Bacterial RecJ exonuclease; PFAM: Phosphoesterase, RecJ-like; Phosphoesterase, DHHA1. | recA protein; Can catalyze the hydrolysis of ATP in the presence of single- stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage; Belongs to the RecA family. | 0.435 |