STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
bioBBiotin synthase; Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical-based mechanism; Belongs to the radical SAM superfamily. Biotin synthase family. (324 aa)    
Predicted Functional Partners:
bioD
Dethiobiotin synthase; Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8- diaminopelargonic acid (DAPA) to form an ureido ring.
 
 
 0.998
bioA
Adenosylmethionine-8-amino-7-oxononanoate aminotransferase; Catalyzes the transfer of the alpha-amino group from S- adenosyl-L-methionine (SAM) to 7-keto-8-aminopelargonic acid (KAPA) to form 7,8-diaminopelargonic acid (DAPA). It is the only animotransferase known to utilize SAM as an amino donor; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. BioA subfamily.
  
 0.993
birA
biotin/acetyl-CoA-carboxylase ligase; Acts both as a biotin--[acetyl-CoA-carboxylase] ligase and a repressor; Belongs to the biotin--protein ligase family.
 
 
 0.982
Dde_2662
8-amino-7-oxononanoate synthase; KEGG: dvm:DvMF_1008 aminotransferase class I and II; PFAM: Aminotransferase, class I/II.
 
  
 0.964
Dde_2082
KEGG: dvm:DvMF_0418 biotin/acetyl-CoA-carboxylase ligase; TIGRFAM: Biotin--acetyl-CoA-carboxylase ligase; PFAM: Biotin/lipoate A/B protein ligase.
  
 
 0.919
Dde_2277
Radical SAM domain protein; KEGG: dsa:Desal_0368 biotin synthase; PFAM: Radical SAM; SMART: Elongator protein 3/MiaB/NifB.
     
  0.900
Dde_2657
PFAM: Beta-hydroxyacyl-(acyl-carrier-protein) dehydratase, FabA/FabZ; KEGG: din:Selin_0491 beta-hydroxyacyl-(acyl-carrier-protein) dehydratase FabA/FabZ.
  
  
 0.825
Dde_2658
PFAM: Short-chain dehydrogenase/reductase SDR; KEGG: dvm:DvMF_1004 short-chain dehydrogenase/reductase SDR.
     
 0.814
Dde_2660
KEGG: dvm:DvMF_1006 beta-ketoacyl synthase; PFAM: Beta-ketoacyl synthase, C-terminal; Beta-ketoacyl synthase, N-terminal; Belongs to the thiolase-like superfamily. Beta-ketoacyl-ACP synthases family.
  
  
 0.787
Dde_2659
PFAM: Phosphopantetheine-binding; KEGG: dvl:Dvul_0686 acyl carrier protein.
     
 0.769
Your Current Organism:
Desulfovibrio alaskensis
NCBI taxonomy Id: 207559
Other names: D. alaskensis G20, Desulfovibrio alaskensis G20, Desulfovibrio alaskensis str. G20, Desulfovibrio alaskensis strain G20, Desulfovibrio desulfuricans subsp. desulfuricans str. G20
Server load: low (36%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.