STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
cutDGlycyl-radical enzyme activating protein family; Catalyzes activation of the choline trimethylamine-lyase CutC under anaerobic conditions by generation of an organic free radical on a glycine residue, via a homolytic cleavage of S-adenosyl-L-methionine (SAM). Is involved in the anaerobic choline utilization pathway that allows D.alaskensis to grow on choline as a source of carbon and energy; Belongs to the organic radical-activating enzymes family. (310 aa)    
Predicted Functional Partners:
cutC
Formate C-acetyltransferase; Glycine radical enzyme that catalyzes the cleavage of a C-N bond in choline, producing trimethylamine (TMA) and acetaldehyde. Is involved in the anaerobic choline utilization pathway that allows D.alaskensis to grow on choline as a source of carbon and energy. Is strictly specific for choline as substrate.
 
  
 0.970
Dde_3039
PFAM: Pyruvate formate-lyase, PFL; Formate C-acetyltransferase glycine radical; KEGG: pca:Pcar_0937 pyruvate-formate lyase.
 
  
 0.922
Dde_1273
PFAM: Pyruvate formate-lyase, PFL; Formate C-acetyltransferase glycine radical; KEGG: dvu:DVU2824 formate acetyltransferase.
 
  
 0.894
Dde_3055
PFAM: Pyruvate formate-lyase, PFL; Formate C-acetyltransferase glycine radical; KEGG: cno:NT01CX_1220 pyruvate formate-lyase.
 
  
 0.894
Dde_3279
KEGG: dsa:Desal_0471 acetaldehyde dehydrogenase (acetylating); TIGRFAM: Acetaldehyde dehydrogenase, acetylating.
 
  
 0.752
Dde_3283
KEGG: dsa:Desal_0467 acetaldehyde dehydrogenase-like protein.
 
  
 0.701
Dde_3280
KEGG: dsa:Desal_0470 microcompartments protein; PFAM: Microcompartment protein, bacteria; SMART: Microcompartment protein, bacteria.
     
 0.630
Dde_3078
Fe-S cluster assembly protein NifU; May be involved in the formation or repair of [Fe-S] clusters present in iron-sulfur proteins.
  
  
 0.555
Dde_3237
SMART: Pyruvate-flavodoxin oxidoreductase, EKR domain; TIGRFAM: Pyruvate-flavodoxin oxidoreductase; KEGG: dvl:Dvul_0348 pyruvate flavodoxin/ferredoxin oxidoreductase domain-containing protein; PFAM: Pyruvate flavodoxin/ferredoxin oxidoreductase, N-terminal; Pyruvate-flavodoxin oxidoreductase, EKR domain; 4Fe-4S ferredoxin, iron-sulphur binding, subgroup; Thiamine pyrophosphate enzyme, C-terminal TPP-binding; Pyruvate/ketoisovalerate oxidoreductase; Belongs to the pyruvate:ferredoxin/flavodoxin oxidoreductase family.
     
 0.509
Dde_3278
KEGG: dsa:Desal_0472 microcompartments protein; PFAM: Microcompartment protein, bacteria; SMART: Microcompartment protein, bacteria.
     
 0.498
Your Current Organism:
Desulfovibrio alaskensis
NCBI taxonomy Id: 207559
Other names: D. alaskensis G20, Desulfovibrio alaskensis G20, Desulfovibrio alaskensis str. G20, Desulfovibrio alaskensis strain G20, Desulfovibrio desulfuricans subsp. desulfuricans str. G20
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