STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
nirSNitrite reductase precursor; Product name confidence: Class 1 (Function experimentally demonstrated in P. aeruginosa). (568 aa)    
Predicted Functional Partners:
norC
Nitric-oxide reductase subunit C; Component of the anaerobic respiratory chain that transforms nitrate to dinitrogen (denitrification).
 
 0.999
norB
Nitric-oxide reductase subunit B; Component of the anaerobic respiratory chain that transforms nitrate to dinitrogen (denitrification). NorB is the catalytic subunit of the enzyme complex. Shows proton pump activity across the membrane in denitrifying bacterial cells. The mononitrogen reduction is probably coupled to electron transport phosphorylation (By similarity).
 
 0.999
nirC
Probable c-type cytochrome precursor; Monoheme c-type cytochrome.
 
 
 0.998
nirM
Cytochrome c-551 precursor; Electron donor for cytochrome cd1 in nitrite and nitrate respiration.
  
  
 0.998
nirJ
Heme d1 biosynthesis protein NirJ; Product name confidence: Class 1 (Function experimentally demonstrated in P. aeruginosa).
 
  
 0.997
nirL
Heme d1 biosynthesis protein NirL; Product name confidence: Class 1 (Function experimentally demonstrated in P. aeruginosa).
 
  
 0.995
narG
Respiratory nitrate reductase alpha chain; Product name confidence: Class 2 (High similarity to functionally studied protein); Belongs to the prokaryotic molybdopterin-containing oxidoreductase family.
  
 0.993
napA
Periplasmic nitrate reductase protein NapA; Catalytic subunit of the periplasmic nitrate reductase complex NapAB. Receives electrons from NapB and catalyzes the reduction of nitrate to nitrite; Belongs to the prokaryotic molybdopterin-containing oxidoreductase family. NasA/NapA/NarB subfamily.
 
 0.992
nosZ
Nitrous-oxide reductase precursor; Nitrous-oxide reductase is part of a bacterial respiratory system which is activated under anaerobic conditions in the presence of nitrate or nitrous oxide; Belongs to the NosZ family.
 
  
 0.992
nirN
Probable c-type cytochrome; Product name confidence: Class 3 (Function proposed based on presence of conserved amino acid motif, structural feature or limited sequence similarity to an experimentally studied gene).
 
 
0.990
Your Current Organism:
Pseudomonas aeruginosa
NCBI taxonomy Id: 208964
Other names: P. aeruginosa PAO1, Pseudomonas aeruginosa PAO1, Pseudomonas sp. PAO1
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