STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
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[Homology]
Score
norBNitric-oxide reductase subunit B; Component of the anaerobic respiratory chain that transforms nitrate to dinitrogen (denitrification). NorB is the catalytic subunit of the enzyme complex. Shows proton pump activity across the membrane in denitrifying bacterial cells. The mononitrogen reduction is probably coupled to electron transport phosphorylation (By similarity). (466 aa)    
Predicted Functional Partners:
nirS
Nitrite reductase precursor; Product name confidence: Class 1 (Function experimentally demonstrated in P. aeruginosa).
 
 0.999
norC
Nitric-oxide reductase subunit C; Component of the anaerobic respiratory chain that transforms nitrate to dinitrogen (denitrification).
 
 0.999
nosZ
Nitrous-oxide reductase precursor; Nitrous-oxide reductase is part of a bacterial respiratory system which is activated under anaerobic conditions in the presence of nitrate or nitrous oxide; Belongs to the NosZ family.
 
 
 0.999
PA0525
Probable dinitrification protein NorD; Component of the anaerobic respiratory chain that transforms nitrate to dinitrogen (denitrification). Function unknown, but essential for the denitrification process.
 
  
 0.996
nosR
Regulatory protein NosR; Transcriptional activator of the nitrous-oxide reductase gene NosZ.
 
  
 0.996
nirQ
Regulatory protein NirQ; Activator of nitrite and nitric oxide reductases.
 
  
 0.991
nirN
Probable c-type cytochrome; Product name confidence: Class 3 (Function proposed based on presence of conserved amino acid motif, structural feature or limited sequence similarity to an experimentally studied gene).
 
 
 0.986
nirF
Heme d1 biosynthesis protein NirF; Required for the biosynthesis of heme d1 of nitrite reductase. Could have a dehydrogenase activity yielding sirohydrochlorin from precorrin-2 or dehydrogenation of propionate side chain C17.
 
  
 0.986
nirC
Probable c-type cytochrome precursor; Monoheme c-type cytochrome.
 
 
 0.981
nosD
NosD protein; Required for the assembly of the copper chromophores of nitrous oxide reductase. Could be part of the ABC transporter complex NosDFY.
  
  
 0.977
Your Current Organism:
Pseudomonas aeruginosa
NCBI taxonomy Id: 208964
Other names: P. aeruginosa PAO1, Pseudomonas aeruginosa PAO1, Pseudomonas sp. PAO1
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