node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
PA0275 | cyaB | PA0275 | PA3217 | Probable transcriptional regulator; Product name confidence: Class 3 (Function proposed based on presence of conserved amino acid motif, structural feature or limited sequence similarity to an experimentally studied gene). | CyaB; Product name confidence: Class 1 (Function experimentally demonstrated in P. aeruginosa). | 0.962 |
PA0275 | gacS | PA0275 | PA0928 | Probable transcriptional regulator; Product name confidence: Class 3 (Function proposed based on presence of conserved amino acid motif, structural feature or limited sequence similarity to an experimentally studied gene). | Sensor/response regulator hybrid; Product name confidence: Class 2 (High similarity to functionally studied protein). | 0.518 |
PA0275 | vfr | PA0275 | PA0652 | Probable transcriptional regulator; Product name confidence: Class 3 (Function proposed based on presence of conserved amino acid motif, structural feature or limited sequence similarity to an experimentally studied gene). | Transcriptional regulator Vfr; Can bind cyclic AMP. Is a global regulator of virulence factor expression and is required for exotoxin A and protease production. | 0.930 |
cpdA | cyaA | PA4969 | PA5272 | Cyclic AMP (cAMP) Phosphodiesterase, CpdA; Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes. | Adenylate cyclase; Product name confidence: Class 2 (High similarity to functionally studied protein). | 0.994 |
cpdA | cyaB | PA4969 | PA3217 | Cyclic AMP (cAMP) Phosphodiesterase, CpdA; Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes. | CyaB; Product name confidence: Class 1 (Function experimentally demonstrated in P. aeruginosa). | 0.993 |
cpdA | fimL | PA4969 | PA1822 | Cyclic AMP (cAMP) Phosphodiesterase, CpdA; Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes. | Hypothetical protein; Product name confidence: Class 4 (Homologs of previously reported genes of unknown function, or no similarity to any previously reported sequences). | 0.808 |
cpdA | gacS | PA4969 | PA0928 | Cyclic AMP (cAMP) Phosphodiesterase, CpdA; Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes. | Sensor/response regulator hybrid; Product name confidence: Class 2 (High similarity to functionally studied protein). | 0.465 |
cpdA | vfr | PA4969 | PA0652 | Cyclic AMP (cAMP) Phosphodiesterase, CpdA; Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes. | Transcriptional regulator Vfr; Can bind cyclic AMP. Is a global regulator of virulence factor expression and is required for exotoxin A and protease production. | 0.911 |
cyaA | cpdA | PA5272 | PA4969 | Adenylate cyclase; Product name confidence: Class 2 (High similarity to functionally studied protein). | Cyclic AMP (cAMP) Phosphodiesterase, CpdA; Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes. | 0.994 |
cyaA | cyaB | PA5272 | PA3217 | Adenylate cyclase; Product name confidence: Class 2 (High similarity to functionally studied protein). | CyaB; Product name confidence: Class 1 (Function experimentally demonstrated in P. aeruginosa). | 0.989 |
cyaA | exsA | PA5272 | PA1713 | Adenylate cyclase; Product name confidence: Class 2 (High similarity to functionally studied protein). | Transcriptional regulator ExsA; Appears to be required for induction of exoenzyme S synthesis above a low basal level. | 0.418 |
cyaA | fimL | PA5272 | PA1822 | Adenylate cyclase; Product name confidence: Class 2 (High similarity to functionally studied protein). | Hypothetical protein; Product name confidence: Class 4 (Homologs of previously reported genes of unknown function, or no similarity to any previously reported sequences). | 0.643 |
cyaA | vfr | PA5272 | PA0652 | Adenylate cyclase; Product name confidence: Class 2 (High similarity to functionally studied protein). | Transcriptional regulator Vfr; Can bind cyclic AMP. Is a global regulator of virulence factor expression and is required for exotoxin A and protease production. | 0.947 |
cyaB | PA0275 | PA3217 | PA0275 | CyaB; Product name confidence: Class 1 (Function experimentally demonstrated in P. aeruginosa). | Probable transcriptional regulator; Product name confidence: Class 3 (Function proposed based on presence of conserved amino acid motif, structural feature or limited sequence similarity to an experimentally studied gene). | 0.962 |
cyaB | cpdA | PA3217 | PA4969 | CyaB; Product name confidence: Class 1 (Function experimentally demonstrated in P. aeruginosa). | Cyclic AMP (cAMP) Phosphodiesterase, CpdA; Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes. | 0.993 |
cyaB | cyaA | PA3217 | PA5272 | CyaB; Product name confidence: Class 1 (Function experimentally demonstrated in P. aeruginosa). | Adenylate cyclase; Product name confidence: Class 2 (High similarity to functionally studied protein). | 0.989 |
cyaB | exsA | PA3217 | PA1713 | CyaB; Product name confidence: Class 1 (Function experimentally demonstrated in P. aeruginosa). | Transcriptional regulator ExsA; Appears to be required for induction of exoenzyme S synthesis above a low basal level. | 0.595 |
cyaB | fimL | PA3217 | PA1822 | CyaB; Product name confidence: Class 1 (Function experimentally demonstrated in P. aeruginosa). | Hypothetical protein; Product name confidence: Class 4 (Homologs of previously reported genes of unknown function, or no similarity to any previously reported sequences). | 0.931 |
cyaB | gacS | PA3217 | PA0928 | CyaB; Product name confidence: Class 1 (Function experimentally demonstrated in P. aeruginosa). | Sensor/response regulator hybrid; Product name confidence: Class 2 (High similarity to functionally studied protein). | 0.710 |
cyaB | vfr | PA3217 | PA0652 | CyaB; Product name confidence: Class 1 (Function experimentally demonstrated in P. aeruginosa). | Transcriptional regulator Vfr; Can bind cyclic AMP. Is a global regulator of virulence factor expression and is required for exotoxin A and protease production. | 0.995 |