STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
nadBL-aspartate oxidase; Catalyzes the oxidation of L-aspartate to iminoaspartate. (538 aa)    
Predicted Functional Partners:
nadA
Quinolinate synthetase A; Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate; Belongs to the quinolinate synthase A family. Type 1 subfamily.
 
 0.999
nadC
Nicotinate-nucleotide pyrophosphorylase; Involved in the catabolism of quinolinic acid (QA). Belongs to the NadC/ModD family.
  
 0.999
nadX
Hypothetical protein; Specifically catalyzes the NAD or NADP-dependent dehydrogenation of L-aspartate to iminoaspartate.
     
 0.959
aspA
Aspartate ammonia-lyase; Product name confidence: Class 2 (High similarity to functionally studied protein); Belongs to the class-II fumarase/aspartase family. Aspartase subfamily.
   
 0.942
ansA
Product name confidence: Class 2 (High similarity to functionally studied protein).
   
 
 0.937
purA
Adenylosuccinate synthetase; Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP; Belongs to the adenylosuccinate synthetase family.
  
 
 0.929
argG
Argininosuccinate synthase; Product name confidence: Class 2 (High similarity to functionally studied protein); Belongs to the argininosuccinate synthase family. Type 1 subfamily.
     
 0.919
ansB
Glutaminase-asparaginase; Product name confidence: Class 2 (High similarity to functionally studied protein); Belongs to the asparaginase 1 family.
   
 
 0.915
PA3797
Conserved hypothetical protein; Product name confidence: Class 4 (Homologs of previously reported genes of unknown function, or no similarity to any previously reported sequences).
  
 
 0.914
pyrB
Aspartate carbamoyltransferase; Product name confidence: Class 2 (High similarity to functionally studied protein).
   
 
 0.912
Your Current Organism:
Pseudomonas aeruginosa
NCBI taxonomy Id: 208964
Other names: P. aeruginosa PAO1, Pseudomonas aeruginosa PAO1, Pseudomonas sp. PAO1
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.