node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
PA1245 | aprA | PA1245 | PA1249 | Hypothetical protein; Product name confidence: Class 4 (Homologs of previously reported genes of unknown function, or no similarity to any previously reported sequences). | Alkaline metalloproteinase precursor; Product name confidence: Class 1 (Function experimentally demonstrated in P. aeruginosa); Belongs to the peptidase M10B family. | 0.744 |
PA1245 | aprD | PA1245 | PA1246 | Hypothetical protein; Product name confidence: Class 4 (Homologs of previously reported genes of unknown function, or no similarity to any previously reported sequences). | Alkaline protease secretion protein AprD; Involved in the secretion of alkaline protease; Belongs to the ABC transporter superfamily. Alkaline protease exporter (TC 3.A.1.110.4) family. | 0.951 |
PA1245 | aprE | PA1245 | PA1247 | Hypothetical protein; Product name confidence: Class 4 (Homologs of previously reported genes of unknown function, or no similarity to any previously reported sequences). | Alkaline protease secretion protein AprE; Involved in the secretion of alkaline protease; Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family. | 0.933 |
PA1245 | aprF | PA1245 | PA1248 | Hypothetical protein; Product name confidence: Class 4 (Homologs of previously reported genes of unknown function, or no similarity to any previously reported sequences). | Alkaline protease secretion outer membrane protein AprF precursor; Involved in the secretion of alkaline protease; Belongs to the outer membrane factor (OMF) (TC 1.B.17) family. | 0.877 |
PA1245 | aprI | PA1245 | PA1250 | Hypothetical protein; Product name confidence: Class 4 (Homologs of previously reported genes of unknown function, or no similarity to any previously reported sequences). | Alkaline proteinase inhibitor AprI; Inhibitor of the alkaline protease. It forms a non-covalent bond with the protease and may prevent its autocatalytic cleavage in the periplasm (By similarity). | 0.901 |
PA1784 | algL | PA1784 | PA3547 | Hypothetical protein; Product name confidence: Class 4 (Homologs of previously reported genes of unknown function, or no similarity to any previously reported sequences). | Poly(beta-d-mannuronate) lyase precursor AlgL; Catalyzes the depolymerization of alginate by cleaving the beta-1,4 glycosidic bond between two adjacent sugar residues via a beta-elimination mechanism. May serve to degrade mislocalized alginate that is trapped in the periplasmic space. Acts preferentially on non-acetylated alginate or its precursor mannuronan. Is able to catalyze cleavage adjacent to either mannuronate or guluronate residues in alginate. Exhaustive digestion of alginate by AlgL generates dimeric and trimeric products. In addition to its enzymatic function, AlgL appears [...] | 0.825 |
PA1784 | aprI | PA1784 | PA1250 | Hypothetical protein; Product name confidence: Class 4 (Homologs of previously reported genes of unknown function, or no similarity to any previously reported sequences). | Alkaline proteinase inhibitor AprI; Inhibitor of the alkaline protease. It forms a non-covalent bond with the protease and may prevent its autocatalytic cleavage in the periplasm (By similarity). | 0.562 |
PA3649 | aprA | PA3649 | PA1249 | Conserved hypothetical protein; Product name confidence: Class 4 (Homologs of previously reported genes of unknown function, or no similarity to any previously reported sequences); Belongs to the peptidase M50B family. | Alkaline metalloproteinase precursor; Product name confidence: Class 1 (Function experimentally demonstrated in P. aeruginosa); Belongs to the peptidase M10B family. | 0.864 |
PA3649 | aprI | PA3649 | PA1250 | Conserved hypothetical protein; Product name confidence: Class 4 (Homologs of previously reported genes of unknown function, or no similarity to any previously reported sequences); Belongs to the peptidase M50B family. | Alkaline proteinase inhibitor AprI; Inhibitor of the alkaline protease. It forms a non-covalent bond with the protease and may prevent its autocatalytic cleavage in the periplasm (By similarity). | 0.587 |
PA3649 | fliC | PA3649 | PA1092 | Conserved hypothetical protein; Product name confidence: Class 4 (Homologs of previously reported genes of unknown function, or no similarity to any previously reported sequences); Belongs to the peptidase M50B family. | Flagellin type B; Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella. | 0.414 |
algL | PA1784 | PA3547 | PA1784 | Poly(beta-d-mannuronate) lyase precursor AlgL; Catalyzes the depolymerization of alginate by cleaving the beta-1,4 glycosidic bond between two adjacent sugar residues via a beta-elimination mechanism. May serve to degrade mislocalized alginate that is trapped in the periplasmic space. Acts preferentially on non-acetylated alginate or its precursor mannuronan. Is able to catalyze cleavage adjacent to either mannuronate or guluronate residues in alginate. Exhaustive digestion of alginate by AlgL generates dimeric and trimeric products. In addition to its enzymatic function, AlgL appears [...] | Hypothetical protein; Product name confidence: Class 4 (Homologs of previously reported genes of unknown function, or no similarity to any previously reported sequences). | 0.825 |
algL | aprI | PA3547 | PA1250 | Poly(beta-d-mannuronate) lyase precursor AlgL; Catalyzes the depolymerization of alginate by cleaving the beta-1,4 glycosidic bond between two adjacent sugar residues via a beta-elimination mechanism. May serve to degrade mislocalized alginate that is trapped in the periplasmic space. Acts preferentially on non-acetylated alginate or its precursor mannuronan. Is able to catalyze cleavage adjacent to either mannuronate or guluronate residues in alginate. Exhaustive digestion of alginate by AlgL generates dimeric and trimeric products. In addition to its enzymatic function, AlgL appears [...] | Alkaline proteinase inhibitor AprI; Inhibitor of the alkaline protease. It forms a non-covalent bond with the protease and may prevent its autocatalytic cleavage in the periplasm (By similarity). | 0.550 |
algL | fliC | PA3547 | PA1092 | Poly(beta-d-mannuronate) lyase precursor AlgL; Catalyzes the depolymerization of alginate by cleaving the beta-1,4 glycosidic bond between two adjacent sugar residues via a beta-elimination mechanism. May serve to degrade mislocalized alginate that is trapped in the periplasmic space. Acts preferentially on non-acetylated alginate or its precursor mannuronan. Is able to catalyze cleavage adjacent to either mannuronate or guluronate residues in alginate. Exhaustive digestion of alginate by AlgL generates dimeric and trimeric products. In addition to its enzymatic function, AlgL appears [...] | Flagellin type B; Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella. | 0.426 |
aprA | PA1245 | PA1249 | PA1245 | Alkaline metalloproteinase precursor; Product name confidence: Class 1 (Function experimentally demonstrated in P. aeruginosa); Belongs to the peptidase M10B family. | Hypothetical protein; Product name confidence: Class 4 (Homologs of previously reported genes of unknown function, or no similarity to any previously reported sequences). | 0.744 |
aprA | PA3649 | PA1249 | PA3649 | Alkaline metalloproteinase precursor; Product name confidence: Class 1 (Function experimentally demonstrated in P. aeruginosa); Belongs to the peptidase M10B family. | Conserved hypothetical protein; Product name confidence: Class 4 (Homologs of previously reported genes of unknown function, or no similarity to any previously reported sequences); Belongs to the peptidase M50B family. | 0.864 |
aprA | aprD | PA1249 | PA1246 | Alkaline metalloproteinase precursor; Product name confidence: Class 1 (Function experimentally demonstrated in P. aeruginosa); Belongs to the peptidase M10B family. | Alkaline protease secretion protein AprD; Involved in the secretion of alkaline protease; Belongs to the ABC transporter superfamily. Alkaline protease exporter (TC 3.A.1.110.4) family. | 0.984 |
aprA | aprE | PA1249 | PA1247 | Alkaline metalloproteinase precursor; Product name confidence: Class 1 (Function experimentally demonstrated in P. aeruginosa); Belongs to the peptidase M10B family. | Alkaline protease secretion protein AprE; Involved in the secretion of alkaline protease; Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family. | 0.978 |
aprA | aprF | PA1249 | PA1248 | Alkaline metalloproteinase precursor; Product name confidence: Class 1 (Function experimentally demonstrated in P. aeruginosa); Belongs to the peptidase M10B family. | Alkaline protease secretion outer membrane protein AprF precursor; Involved in the secretion of alkaline protease; Belongs to the outer membrane factor (OMF) (TC 1.B.17) family. | 0.967 |
aprA | aprI | PA1249 | PA1250 | Alkaline metalloproteinase precursor; Product name confidence: Class 1 (Function experimentally demonstrated in P. aeruginosa); Belongs to the peptidase M10B family. | Alkaline proteinase inhibitor AprI; Inhibitor of the alkaline protease. It forms a non-covalent bond with the protease and may prevent its autocatalytic cleavage in the periplasm (By similarity). | 0.999 |
aprA | fliC | PA1249 | PA1092 | Alkaline metalloproteinase precursor; Product name confidence: Class 1 (Function experimentally demonstrated in P. aeruginosa); Belongs to the peptidase M10B family. | Flagellin type B; Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella. | 0.929 |