node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
PA5177 | pyrF | PA5177 | PA2876 | Probable hydrolase; Product name confidence: Class 3 (Function proposed based on presence of conserved amino acid motif, structural feature or limited sequence similarity to an experimentally studied gene). | Orotidine 5'-phosphate decarboxylase; Catalyzes the decarboxylation of orotidine 5'-monophosphate (OMP) to uridine 5'-monophosphate (UMP); Belongs to the OMP decarboxylase family. Type 1 subfamily. | 0.904 |
PA5177 | pyrH | PA5177 | PA3654 | Probable hydrolase; Product name confidence: Class 3 (Function proposed based on presence of conserved amino acid motif, structural feature or limited sequence similarity to an experimentally studied gene). | Uridylate kinase; Catalyzes the reversible phosphorylation of UMP to UDP. | 0.900 |
PA5177 | pyrR | PA5177 | PA0403 | Probable hydrolase; Product name confidence: Class 3 (Function proposed based on presence of conserved amino acid motif, structural feature or limited sequence similarity to an experimentally studied gene). | Transcriptional regulator PyrR; Regulates the transcription of the pyrimidine nucleotide (pyr) operon in response to exogenous pyrimidines. | 0.900 |
PA5177 | surE | PA5177 | PA3625 | Probable hydrolase; Product name confidence: Class 3 (Function proposed based on presence of conserved amino acid motif, structural feature or limited sequence similarity to an experimentally studied gene). | Survival protein SurE; Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates; Belongs to the SurE nucleotidase family. | 0.913 |
PA5177 | upp | PA5177 | PA4646 | Probable hydrolase; Product name confidence: Class 3 (Function proposed based on presence of conserved amino acid motif, structural feature or limited sequence similarity to an experimentally studied gene). | Uracil phosphoribosyltransferase; Catalyzes the conversion of uracil and 5-phospho-alpha-D- ribose 1-diphosphate (PRPP) to UMP and diphosphate. | 0.906 |
carA | carB | PA4758 | PA4756 | Carbamoyl-phosphate synthase small chain; Product name confidence: Class 1 (Function experimentally demonstrated in P. aeruginosa); Belongs to the CarA family. | Carbamoylphosphate synthetase large subunit; Product name confidence: Class 1 (Function experimentally demonstrated in P. aeruginosa). | 0.999 |
carA | pyrB | PA4758 | PA0402 | Carbamoyl-phosphate synthase small chain; Product name confidence: Class 1 (Function experimentally demonstrated in P. aeruginosa); Belongs to the CarA family. | Aspartate carbamoyltransferase; Product name confidence: Class 2 (High similarity to functionally studied protein). | 0.999 |
carA | pyrD | PA4758 | PA3050 | Carbamoyl-phosphate synthase small chain; Product name confidence: Class 1 (Function experimentally demonstrated in P. aeruginosa); Belongs to the CarA family. | Dihydroorotate dehydrogenase; Catalyzes the conversion of dihydroorotate to orotate with quinone as electron acceptor; Belongs to the dihydroorotate dehydrogenase family. Type 2 subfamily. | 0.878 |
carA | pyrE | PA4758 | PA5331 | Carbamoyl-phosphate synthase small chain; Product name confidence: Class 1 (Function experimentally demonstrated in P. aeruginosa); Belongs to the CarA family. | Orotate phosphoribosyltransferase; Catalyzes the transfer of a ribosyl phosphate group from 5- phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP). | 0.955 |
carA | pyrF | PA4758 | PA2876 | Carbamoyl-phosphate synthase small chain; Product name confidence: Class 1 (Function experimentally demonstrated in P. aeruginosa); Belongs to the CarA family. | Orotidine 5'-phosphate decarboxylase; Catalyzes the decarboxylation of orotidine 5'-monophosphate (OMP) to uridine 5'-monophosphate (UMP); Belongs to the OMP decarboxylase family. Type 1 subfamily. | 0.937 |
carA | pyrH | PA4758 | PA3654 | Carbamoyl-phosphate synthase small chain; Product name confidence: Class 1 (Function experimentally demonstrated in P. aeruginosa); Belongs to the CarA family. | Uridylate kinase; Catalyzes the reversible phosphorylation of UMP to UDP. | 0.461 |
carA | pyrR | PA4758 | PA0403 | Carbamoyl-phosphate synthase small chain; Product name confidence: Class 1 (Function experimentally demonstrated in P. aeruginosa); Belongs to the CarA family. | Transcriptional regulator PyrR; Regulates the transcription of the pyrimidine nucleotide (pyr) operon in response to exogenous pyrimidines. | 0.825 |
carA | upp | PA4758 | PA4646 | Carbamoyl-phosphate synthase small chain; Product name confidence: Class 1 (Function experimentally demonstrated in P. aeruginosa); Belongs to the CarA family. | Uracil phosphoribosyltransferase; Catalyzes the conversion of uracil and 5-phospho-alpha-D- ribose 1-diphosphate (PRPP) to UMP and diphosphate. | 0.610 |
carB | carA | PA4756 | PA4758 | Carbamoylphosphate synthetase large subunit; Product name confidence: Class 1 (Function experimentally demonstrated in P. aeruginosa). | Carbamoyl-phosphate synthase small chain; Product name confidence: Class 1 (Function experimentally demonstrated in P. aeruginosa); Belongs to the CarA family. | 0.999 |
carB | pyrB | PA4756 | PA0402 | Carbamoylphosphate synthetase large subunit; Product name confidence: Class 1 (Function experimentally demonstrated in P. aeruginosa). | Aspartate carbamoyltransferase; Product name confidence: Class 2 (High similarity to functionally studied protein). | 0.999 |
carB | pyrD | PA4756 | PA3050 | Carbamoylphosphate synthetase large subunit; Product name confidence: Class 1 (Function experimentally demonstrated in P. aeruginosa). | Dihydroorotate dehydrogenase; Catalyzes the conversion of dihydroorotate to orotate with quinone as electron acceptor; Belongs to the dihydroorotate dehydrogenase family. Type 2 subfamily. | 0.986 |
carB | pyrE | PA4756 | PA5331 | Carbamoylphosphate synthetase large subunit; Product name confidence: Class 1 (Function experimentally demonstrated in P. aeruginosa). | Orotate phosphoribosyltransferase; Catalyzes the transfer of a ribosyl phosphate group from 5- phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP). | 0.988 |
carB | pyrF | PA4756 | PA2876 | Carbamoylphosphate synthetase large subunit; Product name confidence: Class 1 (Function experimentally demonstrated in P. aeruginosa). | Orotidine 5'-phosphate decarboxylase; Catalyzes the decarboxylation of orotidine 5'-monophosphate (OMP) to uridine 5'-monophosphate (UMP); Belongs to the OMP decarboxylase family. Type 1 subfamily. | 0.990 |
carB | pyrH | PA4756 | PA3654 | Carbamoylphosphate synthetase large subunit; Product name confidence: Class 1 (Function experimentally demonstrated in P. aeruginosa). | Uridylate kinase; Catalyzes the reversible phosphorylation of UMP to UDP. | 0.837 |
carB | pyrR | PA4756 | PA0403 | Carbamoylphosphate synthetase large subunit; Product name confidence: Class 1 (Function experimentally demonstrated in P. aeruginosa). | Transcriptional regulator PyrR; Regulates the transcription of the pyrimidine nucleotide (pyr) operon in response to exogenous pyrimidines. | 0.967 |