node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
capB | dnaJ | PA3266 | PA4760 | Cold acclimation protein B; Product name confidence: Class 2 (High similarity to functionally studied protein). | DnaJ protein; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and Gr [...] | 0.652 |
capB | dnaK | PA3266 | PA4761 | Cold acclimation protein B; Product name confidence: Class 2 (High similarity to functionally studied protein). | DnaK protein; Acts as a chaperone; Belongs to the heat shock protein 70 family. | 0.639 |
capB | erpA | PA3266 | PA0665 | Cold acclimation protein B; Product name confidence: Class 2 (High similarity to functionally studied protein). | Conserved hypothetical protein; Required for insertion of 4Fe-4S clusters for at least IspG. | 0.632 |
capB | groES | PA3266 | PA4386 | Cold acclimation protein B; Product name confidence: Class 2 (High similarity to functionally studied protein). | GroES protein; Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter. | 0.536 |
capB | grpE | PA3266 | PA4762 | Cold acclimation protein B; Product name confidence: Class 2 (High similarity to functionally studied protein). | Heat shock protein GrpE; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP- [...] | 0.554 |
capB | hfq | PA3266 | PA4944 | Cold acclimation protein B; Product name confidence: Class 2 (High similarity to functionally studied protein). | Hfq; RNA chaperone that binds small regulatory RNA (sRNAs) and mRNAs to facilitate mRNA translational regulation in response to envelope stress, environmental stress and changes in metabolite concentrations. Also binds with high specificity to tRNAs. Belongs to the Hfq family. | 0.541 |
capB | pmbA | PA3266 | PA4472 | Cold acclimation protein B; Product name confidence: Class 2 (High similarity to functionally studied protein). | PmbA protein; Product name confidence: Class 2 (High similarity to functionally studied protein). | 0.497 |
capB | pyrR | PA3266 | PA0403 | Cold acclimation protein B; Product name confidence: Class 2 (High similarity to functionally studied protein). | Transcriptional regulator PyrR; Regulates the transcription of the pyrimidine nucleotide (pyr) operon in response to exogenous pyrimidines. | 0.618 |
capB | rpsL | PA3266 | PA4268 | Cold acclimation protein B; Product name confidence: Class 2 (High similarity to functionally studied protein). | 30S ribosomal protein S12; With S4 and S5 plays an important role in translational accuracy. | 0.572 |
capB | tufA | PA3266 | PA4265 | Cold acclimation protein B; Product name confidence: Class 2 (High similarity to functionally studied protein). | Elongation factor Tu; This protein promotes the GTP-dependent binding of aminoacyl- tRNA to the A-site of ribosomes during protein biosynthesis. | 0.522 |
dnaJ | capB | PA4760 | PA3266 | DnaJ protein; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and Gr [...] | Cold acclimation protein B; Product name confidence: Class 2 (High similarity to functionally studied protein). | 0.652 |
dnaJ | dnaK | PA4760 | PA4761 | DnaJ protein; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and Gr [...] | DnaK protein; Acts as a chaperone; Belongs to the heat shock protein 70 family. | 0.999 |
dnaJ | groES | PA4760 | PA4386 | DnaJ protein; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and Gr [...] | GroES protein; Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter. | 0.983 |
dnaJ | grpE | PA4760 | PA4762 | DnaJ protein; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and Gr [...] | Heat shock protein GrpE; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP- [...] | 0.999 |
dnaJ | rpsL | PA4760 | PA4268 | DnaJ protein; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and Gr [...] | 30S ribosomal protein S12; With S4 and S5 plays an important role in translational accuracy. | 0.644 |
dnaK | capB | PA4761 | PA3266 | DnaK protein; Acts as a chaperone; Belongs to the heat shock protein 70 family. | Cold acclimation protein B; Product name confidence: Class 2 (High similarity to functionally studied protein). | 0.639 |
dnaK | dnaJ | PA4761 | PA4760 | DnaK protein; Acts as a chaperone; Belongs to the heat shock protein 70 family. | DnaJ protein; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and Gr [...] | 0.999 |
dnaK | erpA | PA4761 | PA0665 | DnaK protein; Acts as a chaperone; Belongs to the heat shock protein 70 family. | Conserved hypothetical protein; Required for insertion of 4Fe-4S clusters for at least IspG. | 0.486 |
dnaK | groES | PA4761 | PA4386 | DnaK protein; Acts as a chaperone; Belongs to the heat shock protein 70 family. | GroES protein; Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter. | 0.995 |
dnaK | grpE | PA4761 | PA4762 | DnaK protein; Acts as a chaperone; Belongs to the heat shock protein 70 family. | Heat shock protein GrpE; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP- [...] | 0.999 |