STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
oprPPhosphate-specific outer membrane porin OprP precursor; Anion specific, the binding site has higher affinity for phosphate than chloride ions. Porin O has a higher affinity for polyphosphates (tripolyphosphate and pyrophosphate) while porin P has a higher affinity for orthophosphate. (440 aa)    
Predicted Functional Partners:
oprB
Glucose/carbohydrate outer membrane porin OprB precursor; Substrate-selective channel for a variety of different sugars. Could potentially facilitate the diffusion of diverse compounds, dependent on the presence of a hydroxyl group, but is presumably restricted to carbohydrates. Involved in the transport of glucose, mannitol, fructose and glycerol (sugars able to support the growth of P.aeruginosa). Facilitates glucose diffusion across the outer membrane.
     
 0.955
oprD
Basic amino acid, basic peptide and imipenem outer membrane porin OprD precursor; Porin with a specificity for basic amino acids. Also possesses serine protease activity; Belongs to the outer membrane porin (Opr) (TC 1.B.25) family.
  
  
 0.939
oprF
Major porin and structural outer membrane porin OprF precursor; Has porin activity, forming small water-filled channels. Also has a structural role in determining cell shape and ability to grow in low-osmolarity medium; Belongs to the outer membrane OOP (TC 1.B.6) superfamily.
  
  
 0.906
opdK
Vanillate porin OpdK; Product name confidence: Class 3 (Function proposed based on presence of conserved amino acid motif, structural feature or limited sequence similarity to an experimentally studied gene).
  
   
 0.855
oprE
Anaerobically-induced outer membrane porin OprE precursor; Product name confidence: Class 1 (Function experimentally demonstrated in P. aeruginosa).
      
 0.796
oprH
PhoP/Q and low Mg2+ inducible outer membrane protein H1 precursor; Product name confidence: Class 1 (Function experimentally demonstrated in P. aeruginosa).
      
 0.775
PA1974
Hypothetical protein; Product name confidence: Class 4 (Homologs of previously reported genes of unknown function, or no similarity to any previously reported sequences).
 
    0.767
PA1242
Hypothetical protein; Product name confidence: Class 4 (Homologs of previously reported genes of unknown function, or no similarity to any previously reported sequences).
  
    0.746
oprO
Pyrophosphate-specific outer membrane porin OprO precursor; Anion specific, the binding site has higher affinity for phosphate than chloride ions. Porin O has a higher affinity for polyphosphates (tripolyphosphate and pyrophosphate) while porin P has a higher affinity for orthophosphate; Belongs to the OprO/OprP family.
  
 
0.724
PA0429
Hypothetical protein; Product name confidence: Class 4 (Homologs of previously reported genes of unknown function, or no similarity to any previously reported sequences).
  
     0.691
Your Current Organism:
Pseudomonas aeruginosa
NCBI taxonomy Id: 208964
Other names: P. aeruginosa PAO1, Pseudomonas aeruginosa PAO1, Pseudomonas sp. PAO1
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