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STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
argFOrnithine carbamoyltransferase, anabolic; Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline, which is a substrate for argininosuccinate synthetase (ArgG) involved in the final step in arginine biosynthesis. Belongs to the aspartate/ornithine carbamoyltransferase superfamily. OTCase family. (305 aa)    
Predicted Functional Partners:
argJ
Glutamate N-acetyltransferase; Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis: the synthesis of N-acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate. Belongs to the ArgJ family.
 
 
 0.997
argG
Argininosuccinate synthase; Product name confidence: Class 2 (High similarity to functionally studied protein); Belongs to the argininosuccinate synthase family. Type 1 subfamily.
 
 
 0.994
carB
Carbamoylphosphate synthetase large subunit; Product name confidence: Class 1 (Function experimentally demonstrated in P. aeruginosa).
 
 
 0.989
carA
Carbamoyl-phosphate synthase small chain; Product name confidence: Class 1 (Function experimentally demonstrated in P. aeruginosa); Belongs to the CarA family.
 
 
 0.988
argA
N-acetylglutamate synthase; Product name confidence: Class 2 (High similarity to functionally studied protein); Belongs to the acetyltransferase family. ArgA subfamily.
 
 
 0.988
arcA
Arginine deiminase; Product name confidence: Class 1 (Function experimentally demonstrated in P. aeruginosa).
 
 
 0.979
arcC
Carbamate kinase; Product name confidence: Class 1 (Function experimentally demonstrated in P. aeruginosa).
 
 
 0.975
argC
N-acetyl-gamma-glutamyl-phosphate reductase; Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde. Belongs to the NAGSA dehydrogenase family. Type 1 subfamily.
 
  
 0.969
PA5390
Probable peptidic bond hydrolase; Product name confidence: Class 3 (Function proposed based on presence of conserved amino acid motif, structural feature or limited sequence similarity to an experimentally studied gene).
  
 
 0.962
argE
Acetylornithine deacetylase; Product name confidence: Class 2 (High similarity to functionally studied protein).
  
 
 0.961
Your Current Organism:
Pseudomonas aeruginosa
NCBI taxonomy Id: 208964
Other names: P. aeruginosa PAO1, Pseudomonas aeruginosa PAO1, Pseudomonas sp. PAO1
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