STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
glpDGlycerol-3-phosphate dehydrogenase; Product name confidence: Class 1 (Function experimentally demonstrated in P. aeruginosa). (512 aa)    
Predicted Functional Partners:
glpK
Glycerol kinase; Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate; Belongs to the FGGY kinase family.
 0.998
glpF
Glycerol uptake facilitator protein; Glycerol enters the cell via the glycerol diffusion facilitator protein. This membrane protein facilitates the movement of glycerol across the cytoplasmic membrane.
  
 0.995
glpK1
Probable carbohydrate kinase; Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate; Belongs to the FGGY kinase family.
 0.991
PA1487
Probable carbohydrate kinase; Product name confidence: Class 3 (Function proposed based on presence of conserved amino acid motif, structural feature or limited sequence similarity to an experimentally studied gene); Belongs to the FGGY kinase family.
 
 0.969
plsB
Glycerol-3-phosphate acyltransferase; Product name confidence: Class 2 (High similarity to functionally studied protein); Belongs to the GPAT/DAPAT family.
    
 0.961
gpsA
Glycerol-3-phosphate dehydrogenase, biosynthetic; Product name confidence: Class 2 (High similarity to functionally studied protein); Belongs to the NAD-dependent glycerol-3-phosphate dehydrogenase family.
   
 0.955
plsY
Conserved hypothetical protein; Catalyzes the transfer of an acyl group from acyl-phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP.
     
 0.943
PA3025
Probable FAD-dependent glycerol-3-phosphate dehydrogenase; Product name confidence: Class 3 (Function proposed based on presence of conserved amino acid motif, structural feature or limited sequence similarity to an experimentally studied gene).
  
  
0.931
glpR
Glycerol-3-phosphate regulon repressor; Repressor of the glycerol-3-phosphate regulon.
 
  
 0.878
glpM
Membrane protein GlpM; Could play a role in alginate biosynthesis. Overexpression may be lethal.
     
 0.855
Your Current Organism:
Pseudomonas aeruginosa
NCBI taxonomy Id: 208964
Other names: P. aeruginosa PAO1, Pseudomonas aeruginosa PAO1, Pseudomonas sp. PAO1
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